Publikationen von Helene Kretzmer

Emil Chteinberg, Julia Kolarova, Julia Vogt, Amanda Macamo, Felix Bormann, Helene Kretzmer, Ernst Jan Speel, Joost van den Oord, Christof Schneider, Stephan Stilgenbauer, Jürgen C. Becker, Véronique Winnepenninckx, Erik Biessen, Martin Zenke, Anna Kordelia Kurz, Reiner Siebert, and Axel Zur Hausen , "The significance of PAX5 in Merkel cell carcinoma," The Journal of Pathology: an Official Journal of the Pathological Society of Great Britain and Ireland 266 (1), 81-94 (2025).

Selina Glaser , Anja Fischer, Juan Emilio Martínez-Manjón, Cristina López, Helene Kretzmer, Birgit Burkhardt, Daniel Hübschmann, Michael Hummel, Wolfram Klapper, Julia Kolarova, Markus Kreuz, and German et al Ott, "Subgrouping germinal center-derived B-cell lymphomas based on machine learning-deduced DNA methylation modules," Leukemia 39 (4), 967-971 (2025).

Björn Brändl, Mara Steiger, Carolin Kubelt, Christian Rohrandt, Zhihan Zhu, Maximilian Evers, Gaojianyong Wang, Bernhard Schuldt, Ann-Kristin Afflerbach, Derek Wong, Amy Lum, Skarphedinn Halldorsson, Luna Djirackor, Henning Leske, Svetlana Magadeeva, Romualdas Smicius, Claudia Quedenau, Nils O. Schmidt, Ulrich Schüller, Einar O. Vik-Mo, Martin Proescholdt, Markus J. Riemenschneider, Gelareh Zadeh, Ole Ammerpohl, Stephen Yip, Michael Synowitz, Alena van Bömmel, Helene Kretzmer, and Franz-Josef Müller, "Rapid brain tumor classification from sparse epigenomic data," Nature Medicine 31 (3), 840-848 (2025).

Selina Glaser, Helene Kretzmer, Iris Tatjana Kolassa, Matthias Schlesner, Anja Fischer, Isabell Fenske, Reiner Siebert, and Ole Ammerpohl , "Navigating Illumina DNA methylation data: biology versus technical artefacts," NAR: genomics and bioinformatics 6 (4), Article lqae181 (2024).

Maximilian Stötzel, Chieh-Yu Cheng, Ibrahim A. Ilik, Abhishek Sampath Kumar, Persia Akbari-Omgba, Vera A. van der Weijden, Yufei Zhang, Martin Vingron, Alexander Meissner, Tugce Aktas, Helene Kretzmer, and Aydan Bulut-Karslioglu, "TET activity safeguards pluripotency throughout embryonic dormancy," Nature Structural & Molecular Biology 31 (10), 1625-1639 (2024).

Lara S. Fleischmann, Karolina Nemes, Selina Glaser, Alexandra G. Kouroukli, Matej Boros , Susanne Bens, Sonja Dahlum, Helene Kretzmer, Florian Oyen, Joachim Gerss, Martin Hasselblatt, Michael C. Frühwald, and Reiner Siebert, "Constitutional mosaicism of pathogenic variants in SMARCB1 in a subset of patients with sporadic rhabdoid tumors," Neuro-Oncology: official journal of the World Federation of Neuro-Oncology , Article noae188 (2024).

Philipp M. Roessner, Isabelle Seufert, Vicente Chapaprieta, Ruparoshni Jayabalan, Hannah Briesch, Ramon Massoni-Badosa, Pavle Boskovic, Julian ... Benckendorff, Helene Kretzmer, and Thomas et al Naake, "T-bet suppresses proliferation of malignant B cells in chronic lymphocytic leukemia," Blood 144 (5), 510-524 (2024).

Adriano Bolondi, Benjamin K. Law, Helene Kretzmer, Seher Ipek Gassaloglu, René Buschow, Christina Riemenschneider, Dian Yang, Maria Walther, Jesse V. Veenvliet, Alexander Meissner, Zachary D. Smith, and Michelle M. Chan, "Reconstructing axial progenitor field dynamics in mouse stem cell-derived embryoids," Developmental Cell 59 (12), 1489-1505 (2024).

Nanami S. Sato, Viviane S. Rosa , Aly Makhlouf, Helene Kretzmer, Abhishek Sampath Kumar, Stefanie Grosswendt, Alexandra L. Mattei, Olivia Courbot, Steffen Wolf, Jerome Boulanger, Frederic Langevin, Michal Wiacek, Daniel Karpinski, Alberto Elosegui-Artola, Alexander Meissner, Magdalena Zernicka-Goetz , and Marta N. Shahbazi, "Basal delamination during mouse gastrulation primes pluripotent cells for differentiation," Developmental Cell 59 (10), 1252-1268 (2024).

Hannes Hauswedell , Sara Hetzel, Simon G. Gottlieb , Helene Kretzmer, Alexander Meissner, and Knut Reinert, "Lambda3: homology search for protein, nucleotide, and bisulfite-converted sequences," Bioinformatics 40 (3), Article btae097 (2024).

Weiyin Zhou, Anja Fischer, Martin D. Ogwang, Wen Luo, Patrick Kerchan, Steven J. Reynolds, Constance N. Tenge, Pamela A. Were, Robert T. Kuremu, Walter N. Wekesa, Nestory Masalu, Esther Kawira, Tobias Kinyera, Isaac Otim, Ismail D. Legason, Hadijah Nabalende, Leona W. Ayers, Kishor Bhatia, James J. Goedert, Mateus H. Gouveia, Nathan Cole, Belynda Hicks, Kristine Jones, Michael Hummel, Mathias Schlesner, George Chagaluka, Nora Mutalima, Eric Borgstein, George N. Liomba, Steve Kamiza, Nyengo Mkandawire, Collins Mitambo, Elizabeth M. Molyneux, Robert Newton, Selina Glaser, Helene Kretzmer, Michelle Manning, Amy Hutchinson, Ann W. Hsing, Yao Tettey, Andrew A. Adjei, Stephen J. Chanock, Reiner Siebert, Meredith Yeager, Ludmila Prokunina-Olsson, Mitchell J. Machiela, and Sam M. Mbulaiteye, "Mosaic chromosomal alterations in peripheral blood leukocytes of children in sub-Saharan Africa," Nature Communications 14 (1), 8081 (2023).

Alexandra G. Kouroukli, Nivethika Rajaram, Pavel Bashtrykov, Helene Kretzmer, Reiner Siebert, Albert Jeltsch, and Susanne Bens, "Targeting oncogenic TERT promoter variants by allele-specific epigenome editing," Clinical Epigenetics 15 (1), 183 (2023).

Abhishek Sampath Kumar, Luyi Tian, Adriano Bolondi, Amèlia Aragonés Hernández, Robert Stickels, Helene Kretzmer, Evan Murray, Lars Wittler, Maria Walther, Gabriel Barakat, Leah Haut, Yechiel Elkabetz, Evan Z. Macosko, Léo Guignard, Fei Chen, and Alexander Meissner, "Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis," Nature Genetics 55 (7), 1176-1185 (2023).

Raha Weigert, Sara Hetzel, Nina Bailly, Chuck Haggerty, Ibrahim A. Ilik, Philip Yuk Kwong Yung, Carmen Navarro, Adriano Bolondi, Abhishek Sampath Kumar, Chiara Anania, Björn Brändl, David Meierhofer, Darío G. Lupiáñez, Franz-Josef Müller, Tugce Aktas, Simon J. Elsässer, Helene Kretzmer, Zachary D. Smith, and Alexander Meissner, "Dynamic antagonism between key repressive pathways maintains the placental epigenome," Nature Cell Biology 25 (4), 579-591 (2023).

Alexandro Landshammer, Adriano Bolondi, Helene Kretzmer, Christian Much, Rene Buschow, Alina Rose, Hua-Jun Wu, Sebastian D. Mackowiak, Bjoern Braendl, Pay Gießelmann, Rosaria Tornisiello, Krishna Mohan Parsi, Jack Huey, Thorsten Mielke, David Meierhofer, René Maehr, Denes Hnisz, Franziska Michor, John L. Rinn, and Alexander Meissner, "T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation," eLife 12, e83077 (2023).

Binyamin A. Knisbacher, Ziao Lin, Cynthia K. Hahn, Ferran Nadeu, Martí Duran-Ferrer, Kristen E. Stevenson, Eugen Tausch, Julio Delgado, Alex Barbera-Mourelle, Amaro Taylor-Weiner, Pablo Bousquets-Muñoz, Ander Diaz-Navarro, Andrew Dunford, Shankara Anand, Helene Kretzmer, Jesus Gutierrez-Abril, Sara López-Tamargo, Stacey M. Fernandes, Clare Sun, Mariela Sivina, Laura Z. Rassenti, Christof Schneider, Shuqiang Li, Laxmi Parida, Alexander Meissner, François Aguet , Jan A. Burger, Adrian Wiestner, Thomas J. Kipps, Jennifer R. Brown, Michael Hallek, Chip Stewart, Donna S. Neuberg, José I. Martín-Subero , Xose S. Puente, Stephan Stilgenbauer, Catherine J. Wu, Elias Campo, and Gad Getz, "Molecular map of chronic lymphocytic leukemia and its impact on outcome," Nature Genetics 54, 1664-1674 (2022).

Alexandro Landshammer, Adriano Bolondi, Helene Kretzmer, Christian Much, Rene Buschow, Alina Rose, Hua-Jun Wu, Sebastian Mackowiak, Bjoern Braendl, Pay Giesselmann, Rosaria Tornisiello, Krishna Mohan Parsi, Jack Huey, Thorsten Mielke, David Meierhofer, René Maehr, Denes Hnisz, Franziska Michor, John L. Rinn, and Alexander Meissner, "Discovery and characterization of LNCSOX17 as an essential regulator in human endoderm formation," bioRxiv (Preprint Server) (2022).

Vahid Asimi, Abhishek Sampath Kumar, Henri Niskanen, Christina Riemenschneider, Sara Hetzel, Julian Naderi, Nina Fasching, Niko Popitsch, Manyu Du, Helene Kretzmer, Zachary D. Smith, Raha Weigert, Maria Walther, Sainath Mamde, David Meierhofer, Lars Wittler, Rene Buschow, Bernd Timmermann, Ibrahim I. Cisse, Stefan L. Ameres, Alexander Meissner, and Denes Hnisz, "Hijacking of transcriptional condensates by endogenous retroviruses," Nature Genetics 54, 1238-1247 (2022).

Sara Hetzel, Alexandra L. Mattei, Helene Kretzmer, Chunxu Qu, Xiang Chen, Yiping Fan, Gang Wu, Kathryn G. Roberts, Selina Luger, Mark Litzow, Jacob Rowe, Elisabeth Paietta, Wendy Stock, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Charles G. Mullighan, and Alexander Meissner, "Acute lymphoblastic leukemia displays a distinct highly methylated genome," Nature Cancer 3 (6), 768-782 (2022).

Maayan Pour, Abhishek Sampath Kumar, Naama Farag, Adriano Bolondi, Helene Kretzmer, Maria Walther, Lars Wittler, Alexander Meissner, and Iftach Nachman, "Emergence and patterning dynamics of mouse-definitive endoderm," iScience 25 (1), 103556 (2022).