Publikationen von Alexander Meissner

Sara Hetzel, Alexandra L. Mattei, Helene Kretzmer, Chunxu Qu, Xiang Chen, Yiping Fan, Gang Wu, Kathryn G. Roberts, Selina Luger, Mark Litzow, Jacob Rowe, Elisabeth Paietta, Wendy Stock, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Charles G. Mullighan, and Alexander Meissner, "Acute lymphoblastic leukemia displays a distinct highly methylated genome," Nature Cancer 3 (6), 768-782 (2022).

Maayan Pour, Abhishek Sampath Kumar, Naama Farag, Adriano Bolondi, Helene Kretzmer, Maria Walther, Lars Wittler, Alexander Meissner, and Iftach Nachman, "Emergence and patterning dynamics of mouse-definitive endoderm," iScience 25 (1), 103556 (2022).

Yung-Hsin Huang, Chun-Wei Chen, Venkatasubramaniam Sundaramurthy, Mikołaj Słabicki, Dapeng Hao, Caroline J. Watson, Ayala Tovy, Jaime M. Reyes, Olga Dakhova, Brielle R. Crovetti, Christina Galonska, Minjung Lee, Lorenzo Brunetti, Yubin Zhou, Katrina Tatton-Brown, Yun Huang, Xiaodong Cheng, Alexander Meissner, Peter J. M. Valk, Lionel Van Maldergem, Mathijs A. Sanders, Jamie R. Blundell, Wei Li, Benjamin L. Ebert, and Margaret A. Goodell, "Systematic profiling of DNMT3A variants reveals protein instability mediated by the DCAF8 E3 ubiquitin ligase adaptor," Cancer Discovery 12 (1), 220-235 (2022).

Anat Biran, Shanye Yin, Helene Kretzmer, Elisa ten Hacken, Salma Parvin, Fabienne Lucas, Mohamed Uduman, Catherine Gutierrez, Nathan ... Dangle, Alexander Meissner, and Catherine J. Wu, "Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia," Cancer Research 81 (24), 6117-6130 (2021).

M. Andres Blanco, David B. Sykes, Lei Gu, Mengjun Wu, Ricardo Petroni, Rahul Karnik, Mathias Wawer, Joshua Rico, Haitao Li, William D. Jacobus, Ashwini Jambhekar, Sihem Cheloufi, Alexander Meissner, Konrad Hochedlinger, David T. Scadden, and Yang Shi, "Chromatin-state barriers enforce an irreversible mammalian cell fate decision," Cell Reports 37 (6), 109967 (2021).

Daniel Andergassen, Zachary D. Smith, Helene Kretzmer, John L. Rinn, and Alexander Meissner, "Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages," Developmental Cell 56 (21), 2995-3005 (2021).

Sara Hetzel, Pay Gießelmann, Knut Reinert, Alexander Meissner, and Helene Kretzmer, "RLM: Fast and simplified extraction of Read-Level Methylation metrics from bisulfite sequencing data," Bioinformatics 37 (21), 3934-3935 (2021).

Hongcang Gu, Ayush T. Raman, Xiaoxue Wang, Federico Gaiti, Ronan Chaligne, Arman W. Mohammad, Aleksandra Alicja Arczewska, Zachary D. Smith, Dan A. Landau, Martin J. Aryee, Alexander Meissner, and Andreas Gnirke, "Smart-RRBS for single-cell methylome and transcriptome analysis," Nature Protocols 16, 4004-4030 (2021).

Masaki Yagi , Fei Ji, Jocelyn Charlton, Simona Cristea, Kathleen Messemer, Naftali Horwitz, Bruno Di Stefano, Nikolaos Tsopoulidis, Michael S. Hoetker, Aaron J. Huebner, Ori Bar-Nur, Albert E. Almada, Masakazu Yamamoto, Anthony Patelunas, David J. Goldhamer, Amy J. Wagers, Franziska Michor, Alexander Meissner, Ruslan I. Sadreyev, and Konrad Hochedlinger, "Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells," Genes and Development 35 (17-18), 1209-1228 (2021).

Hua-Jun Wu, Alexandro Landshammer, Elena K. Stamenova, Adriano Bolondi, Helene Kretzmer, Alexander Meissner, and Franziska Michor, "Topological isolation of developmental regulators in mammalian genomes," Nature Communications 12, 4897 (2021).

Chuck Haggerty, Helene Kretzmer, Christina Riemenschneider, Abhishek Sampath Kumar, Alexandra L. Mattei, Nina Bailly, Judith Gottfreund, Pay Giesselmann, Raha Weigert, Björn Brändl, Pascal Giehr, Rene Buschow, Christina Galonska, Ferdinand von Meyenn, Melissa B. Pappalardi, Michael T. McCabe, Lars Wittler, Claudia Giesecke-Thiel, Thorsten Mielke, David Meierhofer, Bernd Timmermann, Franz-Josef Müller, Jörn Walter, and Alexander Meissner, "Dnmt1 has de novo activity targeted to transposable elements," Nature Structural and Molecular Biology 28 (7), 594-603 (2021).

Adriano Bolondi, Leah Haut, Seher Ipek Gassaloglu, Polly Burton, Helene Kretzmer, Rene Buschow, Alexander Meissner, Bernhard G. Herrmann, and Jesse V. Veenvliet, "Generation of Mouse Pluripotent Stem Cell-derived Trunk-like Structures: An in vitro Model of Post-implantation Embryogenesis," Bio-protocol 11 (11), e4042 (2021).

Marlies P. Rossmann, Karen Hoi, Victoria Chan, Brian J. Abraham, Song Yang, James Mullahoo, Malvina Papanastasiou, Ying Wang, Ilaria Elia, Julie R. Perlin, Elliott J. Hagedorn, Sara Hetzel, Raha Weigert, Sejal Vyas, Partha P. Nag, Lucas B. Sullivan, Curtis R. Warren, Bilguujin Dorjsuren, Eugenia Custo Greig, Isaac Adatto, Chad A. Cowan, Stuart L. Schreiber, Richard A. Young, Alexander Meissner, Marcia C. Haigis, Siegfried Hekimi, Steven A. Carr, and Leonard I. Zon, "Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis," Science 372 (6543), 716-721 (2021).

Heng Pan, Loic Renaud, Ronan Chaligne, Johannes Bloehdorn, Eugen Tausch, Daniel Mertens, Anna Maria Fink, Kirsten Fischer, Chao Zhang, Doron Betel, Andreas Gnirke, Marcin Imielinski, Jerome Moreaux, Michael Hallek, Alexander Meissner, Stephan Stilgenbauer, Catherine J. Wu, Olivier Elemento, and Dan A. Landau, "Discovery of candidate DNA methylation cancer driver genes," Cancer Discovery 11 (9), 2266-2281 (2021).

Helene Kretzmer, Anat Biran, Noelia Purroy, Camilla K. Lemvigh, Kendell Clement, Michaela Gruber, Hongcang Gu, Laura Rassenti, Arman W. Mohammad, Connie Lesnick, Susan L. Slager, Esteban Braggio, Tait D. Shanafelt, Neil E. Kay, Stacey M. Fernandes, Jennifer R. Brown, Lili Wang, Shuqiang Li, Kenneth J. Livak, Donna S. Neuberg, Sven Klages, Bernd Timmermann, Thomas J. Kipps, Elias Campo, Andreas Gnirke, Catherine J. Wu, and Alexander Meissner, "Pre-neoplastic alterations define CLL DNA methylome and persist through disease progression and therapy," Blood Cancer Discovery 2 (1), 54-69 (2021).

Jesse V. Veenvliet, Adriano Bolondi, Helene Kretzmer, Leah Haut, Manuela Scholze-Wittler, Dennis Schifferl, Frederic Koch, Léo Guignard, Abhishek Sampath Kumar, Milena Pustet, Simon Heimann, Rene Buschow, Lars Wittler, Bernd Timmermann, Alexander Meissner, and Bernhard G. Herrmann, "Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites," Science 370 (6522), eaba4937 (2020).

Stefanie Grosswendt, Helene Kretzmer, Zachary D. Smith, Abhishek Sampath Kumar, Sara Hetzel, Lars Wittler, Sven Klages, Bernd Timmermann, Shankar Mukherji, and Alexander Meissner, "Epigenetic regulator function through mouse gastrulation," Nature 584, 102-108 (2020).

Jocelyn Charlton, Eunmi J. Jung, Alexandra L. Mattei, Nina Bailly, Jing Liao, Eric J. Martin, Pay Gießelmann, Björn Brändl, Elena K. Stamenova, Franz-Josef Müller, Evangelos Kiskinis, Andreas Gnirke, Zachary D. Smith, and Alexander Meissner, "TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers," Nature Genetics 52 (8), 819-827 (2020).

The ENCODE Project Consortium, Michael P. Snyder, Thomas R. Gingeras, Jill E. Moore, Zhiping Weng, Mark B. Gerstein, Bing Ren, Ross C. Hardison, John A. Stamatoyannopoulos, Brenton R. Graveley, Elise A. Feingold, Michael J. Pazin, Michael Pagan, Daniel A. Gilchrist, Benjamin C. Hitz, J. Michael Cherry, Bradley E. Bernstein, Eric M. Mendenhall, Daniel R. Zerbino, Adam Frankish, Paul Flicek, Richard M. Myers , and Alex Meissner, "Perspectives on ENCODE," Nature 583, 693-698 (2020).

Masaki Yagi, Mio Kabata, Akito Tanaka, Tomoyo Ukai, Sho Ohta, Kazuhiko Nakabayashi, Masahito Shimizu, Kenichiro Hata, Alexander Meissner, Takuya Yamamoto, and Yasuhiro Yamada, "Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development," Nature Communications 11, 3199 (2020).