Publications of H. Lehrach

Henderson, D.; Ogilvie, L. A.; Hoyle, N.; Keilholz, U.; Lange, B.; Lehrach, H.; OncoTrack, C.; Yaspo, M. L.: Personalized medicine approaches for colon cancer driven by genomics and systems biology: OncoTrack. Biotechnology Journal 9 (9), pp. 1104 - 1114 (2014)

Sultan, M.; Amstislavskiy, V.; Risch, T.; Schütte, M.; Dökel, S.; Ralser, M.; Balzereit, D.; Lehrach, H.; Yaspo, M. L.: Influence of RNA extraction methods and library selection schemes on RNA-seq data. BMC Genomics 15, 15:675 (2014)

Rasche, A.; Lienhard, M.; Yaspo, M.-L.; Lehrach, H.; Herwig, R.: ARH-seq: identification of differential splicing in RNA-seq data. Nucleic Acids Research (London) 42 (14), e110 (2014)

Rykalina, V.; Shadrin, A.; Amstislavskiy, V.; Rogaev, E. I.; Lehrach, H.; Borodina, T. A.: Exome sequencing from nanogram amounts of starting DNA: comparing three approaches. PLoS One 9 (7), e101154 (2014)

Colonna, V.; Ayub, Q.; Chen, Y.; Pagani, L.; Luisi, P.; Pybus, M.; Garrison, E.; Xue, Y.; Tyler-Smith, C.; 1000 Genomes Project, C. et al.; Sudbrak, R.; Albrecht, M.; Amstislavskiy, V.; Borodina, T. A.; Dahl, A.; Davydov, A.; Herwig, R.; Marquardt, P.; Mertes, F.; Nietfeld, W.; Parkhomchuk, D.; Soldatov, A. V.; Timmermann, B.; Tolzmann, M.; Lehrach, H.; Yaspo, M. L.: Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences. Genome Biology: Biology for the Post-Genomic Era 15 (6), R88 (2014)

Hovestadt, V.; Jones, D. T.; Picelli, S.; Wang, W.; Kool, M.; Northcott, P. A.; Sultan, M.; Stachurski, K.; Ryzhova, M.; Warnatz, H.-J. et al.; Ralser, M.; Brun, S.; Bunt, J.; Jager, N.; Kleinheinz, K.; Erkek, S.; Weber, U. D.; Bartholomae, C. C.; von Kalle, C.; Lawerenz, C.; Eils, J.; Koster, J.; Versteeg, R.; Milde, T.; Witt, O.; Schmidt, S.; Wolf, S.; Pietsch, T.; Rutkowski, S.; Scheurlen, W.; Taylor, M. D.; Brors, B.; Felsberg, J.; Reifenberger, G.; Borkhardt, A.; Lehrach, H.; Wechsler-Reya, R. J.; Eils, R.; Yaspo, M. L.; Landgraf, P.; Korshunov, A.; Zapatka, M.; Radlwimmer, B.; Pfister, S. M.; Lichter, P.: Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing. Nature 510 (7506), pp. 537 - 541 (2014)

Delaneau, O.; Marchini, J.; 1000 Genomes Project, C.; Lehrach, H.; Sudbrak, R.; Amstislavskiy, V. S.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B. et al.; Yaspo, M. L.; Herwig, R.: Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel. Nature Communications 5, 5:3934 (2014)

Kähler, C.; Isensee, J.; Hucho, T.; Lehrach, H.; Krobitsch, S.: 5-Fluorouracil affects assembly of stress granules based on RNA incorporation. Nucleic Acids Research (London) 42 (10), pp. 6436 - 6447 (2014)

Kähler, C.; Isensee, J.; Hucho, T.; Lehrach, H.; Krobitsch, S.: 5-Fluorouracil affects assembly of stress granules based on RNA incorporation. Nucleic Acids Research 42 (10), pp. 6436 - 6447 (2014)

Hovestadt , V.; Jones , D.; Picelli , S.; Wang , W.; Kool , M.; Northcott , P. A.; Sultan, M.; Stachurski , K.; Ryzhova , M.; Warnatz, H. J. et al.; Ralser, M.; Brun , S.; Bunt , J.; Jäger , N.; Kleinheinz , K.; Erkek , S.; Weber , U. D.; Bartholomae, C. C.; von Kalle , C.; Lawerenz , C.; Eils , J.; Koster , J.; Versteeg , R.; Milde , T.; Witt , O.; Schmidt , S.; Wolf , S.; Pietsch , T.; Rutkowski, S.; Scheurlen , W.; Taylor , M. B.; Brors , B.; Felsberg , J.; Reifenberger , G.; Borkhardt , A.; Lehrach, H.; Wechsler-Reya , R.; Eils , R.; Yaspo, M.-L.; Landgraf , P.; Korshunov , A.; Zapatka , M.; Radlwimmer , B.; Pfister , S. M.; Lichter , P.: Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing. Nature 26 (510), pp. 537 - 541 (2014)

Rashi-Elkeles, S.; Warnatz, H. J.; Elkon, R.; Kupershtein, A.; Chobod, Y.; Paz, A.; Amstislavskiy, V.; Sultan, M.; Safer, H.; Nietfeld, W. et al.; Lehrach, H.; Shamir, R.; Yaspo, M. L.; Shiloh, Y.: Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation. Science Signaling 7 (325), rs3 (2014)

Hussong, M.; Börno, S.; Kerick, M.; Wunderlich, A.; Franz, A.; Sültmann, H.; Timmermann, B.; Lehrach, H.; Hirsch-Kauffmann, M.; Schweiger, M. R.: The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. Cell Death and Disease 5, 5:e1195 (2014)

Hussong, M.; Börno, S. T.; Kerick, M.; Wunderlich, A.; Franz, A.; Sültmann, H.; Timmermann, B.; Lehrach, H.; Hirsch-Kauffmann, M.; Schweiger, M. R.: The bromodomain protein BRD4 regulates the KEAP1/NRF2 dependent oxidative stress response. Cell Death and Disease 2014 (5), e1195 (2014)

Dohm, J.; Minoche, A. E.; Holtgräwe, D.; Capella-Gutiérrez, S.; Zakrzewski, F.; Tafer, H.; Rupp, O.; Rosleff Sörensen, T.; Stracke, R.; Reinhardt, R. et al.; Goesmann, A.; Kraft, T.; Schulz, B.; Stadler, P.; Schmidt, T.; Gabaldón, T.; Lehrach, H.; Weisshaar, B.; Himmelbauer, H.: The genome of the recently domesticated crop plant sugar beet (Beta vulgaris). Nature 505 (7484), pp. 546 - 549 (2014)

Dohm, J. C.; Minoche, A. E.; Holtgräwe, D.; Capella-Gutierrez, S.; Zakrzewski, F.; Tafer, H.; Rupp, O.; Sorensen, T. R.; Stracke, R.; Reinhardt, R. et al.; Goesmann, A.; Kraft, T.; Schulz, B.; Stadler, P. F.; Schmidt, T.; Gabaldon, T.; Lehrach, H.; Weisshaar, B.; Himmelbauer, H.: The genome of the recently domesticated crop plant sugar beet (Beta vulgaris). Nature 505 (7484), pp. 546 - 549 (2014)

Khurana, E.; Fu, Y.; Colonna, V.; Mu, X. J.; Kang, H. M.; Lappalainen, T.; Sboner, A.; Lochovsky, L.; Chen, J.; Harmanci, A. et al.; Das, J.; Abyzov, A.; Balasubramanian, S.; Beal, K.; Chakravarty, D.; Challis, D.; Chen, Y.; Clarke, D.; Clarke, L.; Cunningham, F.; Evani, U. S.; Flicek, P.; Fragoza, R.; Garrison, E.; Gibbs, R.; Gumus, Z. H.; Herrero, J.; Kitabayashi, N.; Kong, Y.; Lage, K.; Liluashvili, V.; Lipkin, S. M.; MacArthur, D. G.; Marth, G.; Muzny, D.; Pers, T. H.; Ritchie, G. R.; Rosenfeld, J. A.; Sisu, C.; Wei, X.; Wilson, M.; Xue, Y.; Yu, F.; 1000 Genomes Project, C.; Lehrach, H.; Sudbrak, R.; Albrecht, M. W.; Amstislavskiy, V.; Borodina, T. A.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M. L.; Dermitzakis, E. T.; Yu, H.; Rubin, M. A.; Tyler-Smith, C.; Gerstein, M.: Integrative annotation of variants from 1092 humans: application to cancer genomics. Science 342 (6154), p. 1235587 - 1235587 (2013)

Lehrach, H.: DNA sequencing methods in human genetics and disease research. F1000Prime Rep 5, p. 5:34 - 5:34 (2013)

Röhr, C.; Kerick, M.; Fischer, A.; Kuehn, A.; Kashofer, K.; Timmermann, B.; Daskalaki, A.; Meinel, T.; Drichel, D.; Börno, S. et al.; Nowka, A.; Krobitsch, S.; McHardy, A. C.; Kratsch, C.; Becker, T.; Wunderlich, A.; Barmeyer, C.; Viertler, C.; Zatloukal, K.; Wierling, C.; Lehrach, H.; Schweiger, M.-R.: High-Throughput miRNA and mRNA Sequencing of Paired Colorectal Normal, Tumor and Metastasis Tissues and Bioinformatic Modeling of miRNA-1 Therapeutic Applications. PLoS One 8 (7), p. e67461 - e67461 (2013)

Götschel, F.; Berg, D.; Gruber, W.; Bender, C.; Eberl, M.; Friedel, M.; Sonntag, J.; Rungeler, E.; Hache, H.; Wierling, C. K. et al.; Nietfeld, W.; Lehrach, H.; Frischauf, A.; Schwartz-Albiez, R.; Aberger, F.; Korf, U.: Synergism between Hedgehog-GLI and EGFR Signaling in Hedgehog-Responsive Human Medulloblastoma Cells Induces Downregulation of Canonical Hedgehog-Target Genes and Stabilized Expression of GLI1. PLoS One 8 (6), p. e65403 - e65403 (2013)

Zazzu, V.; Regierer, B.; Kühn, A.; Sudbrak, R.; Lehrach, H.: IT Future of Medicine: from molecular analysis to clinical diagnosis and improved treatment. New Biotechnology 30 (4), pp. 362 - 365 (2013)