Publications of David Meierhofer

Hudert, C. A.; Adams, L. A.; Alisi, A.; Anstee, Q. M.; Crudele, A.; Draijer, L. G.; Furse, S.; Hengstler, J. G.; Jenkins, B.; Karnebeek, K. et al.; Kelly, D. A.; Koot, B. G.; Koulman, A.; Meierhofer, D.; Melton, P. E.; Mori, T. A.; Snowden, S. G.; van Mourik, I.; Vreugdenhil, A.; Wiegand, S.; Mann, J. P.: Variants in mitochondrial amidoxime reducing component 1 and hydroxysteroid 17-beta dehydrogenase 13 reduce severity of nonalcoholic fatty liver disease in children and suppress fibrotic pathways through distinct mechanisms. Hepatology Communications 2022, 1955 (2022)

Arnold, M.; Bressin, A.; Jasnovidova, O.; Meierhofer, D.; Mayer, A.: A BRD4-mediated elongation control point primes transcribing RNA polymerase II for 3′-processing and termination. Molecular Cell 81 (17), e13, pp. 3589 - 3603 (2021)

Jiao, L.; Eickhoff, R.; Egners, A.; Jumpertz , S.; Roth, J.; Erdem, M.; Kroh, A.; Duimel, H.; López-Iglesias, C.; Caro, P. et al.; Heij, L. R.; Schmeding, M.; Meierhofer, D.; Neumann, U. P. ..; Cramer, T.: Deletion of mTOR in liver epithelial cells enhances hepatic metastasis of colon cancer. The Journal of Pathology: an Official Journal of the Pathological Society of Great Britain and Ireland, 5768 (2021)

Haggerty, C.; Kretzmer, H.; Riemenschneider, C.; Sampath Kumar, A.; Mattei, A. L.; Bailly, N.; Gottfreund, J.; Giesselmann, P.; Weigert, R.; Brändl, B. et al.; Giehr, P.; Buschow, R.; Galonska, C.; von Meyenn, F.; Pappalardi, M. B.; McCabe, M. T.; Wittler, L.; Giesecke-Thiel, C.; Mielke, T.; Meierhofer, D.; Timmermann, B.; Müller, F.-J.; Walter, J.; Meissner, A.: Dnmt1 has de novo activity targeted to transposable elements. Nature Structural and Molecular Biology 2021 (2021)

Schreyer, S.; Berndt, N.; Eckstein, J.; Mülleder, M.; Hemmati-Sadeghi, S.; Klein, C.; Abuelnor, B.; Panzel, A.; Meierhofer, D.; Spranger, J. et al.; Steiner, B.; Brachs, S.: Dietary-challenged mice with Alzheimer-like pathology show increased energy expenditure and reduced adipocyte hypertrophy and steatosis. Aging 2021, 202978 (2021)

Inak, G.; Rybak-Wolf, A.; Lisowski, P.; Pentimalli, T. M.; Jüttner, R.; Glažar, P.; Uppal, K.; Bottani, E.; Brunetti, D.; Secker, C. et al.; Zink, A.; Meierhofer, D.; Henke , M.-T.; Dey, M.; Ciptasar, U.; Mlody, B.; Hahn, T.; Berruezo-Llacuna, M.; Karaiskos, N.; Di Virgilio, M.; Mayr, J. A.; Wortmann, S. B.; Priller , J.; Gotthardt, M.; Jones , D. P.; Mayatepek, E.; Stenzel, W.; Diecke, S.; Kühn, R.; Wanker , E. E.; Rajewsky, N.; Schuelke, M.; Prigione, A.: Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome. Nature Communications 12, 1929 (2021)

Panconesi, R.; Mauricio , F. C.; Mueller, M.; Meierhofer, D.; Dutkowski, P.; Muiesan, P.; Schlegel, A.: Viability Assessment in Liver Transplantation—What Is the Impact of Dynamic Organ Preservation? Biomedicines 9 (2), 161 (2021)

Kalveram, L.; Schunck, W.-H.; Rothe, M.; Rudolph, B.; Loddenkemper, C.; Holzhütter, H.-G.; Henning, S.; Bufler, P.; Schulz, M.; Meierhofer, D. et al.; Zhang, I. W.; Weylandt, K. H.; Wiegand, S.; Hudert, C. A.: Regulation of the cytochrome P450 epoxyeicosanoid pathway is associated with distinct histologic features in pediatric non-alcoholic fatty liver disease. Prostaglandins, Leukotrienes and Essential Fatty Acids 164, 102229 (2020)

Xiao, Y.; Rabien, A.; Buschow, R.; Amstislavskiy, V.; Busch, J.; Kilic, E.; Villegas, S. L.; Timmermann, B.; Schütte, M.; Mielke, T. et al.; Yaspo, M.-L.; Jung, K.; Meierhofer, D.: Endocytosis-mediated replenishment of amino acids favors cancer cell proliferation and survival in chromophobe renal cell carcinoma. Cancer research: an official organ of the American Association for Cancer Research 80, pp. 5491 - 5501 (2020)

Ilik, I. A.; Malszycki, M.; Lübke, A. K.; Schade, C.; Meierhofer, D.; Aktas, T.: SON and SRRM2 are essential for nuclear speckle formation. eLife 2020 (9), e60579 (2020)

Wei, X.; Franke, J.; Ost, M.; Wardelmann, K.; Börno, S.; Timmermann, B.; Meierhofer, D.; Kleinridders, A.; Klaus, S.; Stricker, S.: Cell autonomous requirement of neurofibromin (Nf1) for postnatal muscle hypertrophic growth and metabolic homeostasis. Journal of Cachexia, Sarcopenia and Muscle 2020, 12632 (2020)

Berndt, N.; Eckstein, J.; Heucke, N.; Wuensch, T.; Gajowski, R.; Stockmann, M.; Meierhofer, D.; Holzhütter, H.-G.: Metabolic Heterogeneity of Human Hepatocellular Carcinoma (HCC): Implications for Personalized Pharmacological Treatment. The FEBS Journal 2020, 15587 (2020)

Key, J.; Sen, N. E.; Arsović , A.; Krämer, S.; Hülse, R.; Khan, N. N.; Meierhofer, D.; Gispert, S.; Koepf, G.; Auburger, G.: Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence. Cells 9 (10), 2229 (2020)

Schlegel, A.; Muller, X.; Mueller, M.; Stepanova, A.; Kron, P.; de Rougemont, O.; Muiesan, P.; Clavien, P.-A.; Galkin, A.; Meierhofer, D. et al.; Dutkowski, P.: Hypothermic oxygenated perfusion protects from mitochondrial injury before liver transplantation. EBioMedicine 60, 103014 (2020)

Xiao, Y.; Clima, R.; Busch, J.; Rabien, A.; Kilic, E.; Villegas, S. L.; Timmermann, B.; Attimonelli, M.; Jung, K.; Meierhofer, D.: Decreased mitochondrial DNA content drives OXPHOS dysregulation in chromophobe renal cell carcinoma. Cancer research: an official organ of the American Association for Cancer Research, CAN-20-0754 (2020)

Hudert, C. A.; Alisi, A.; Anstee, Q. M.; Crudele, A.; Draijer, L. G.; EU-PNAFLD, I.; Furse, S.; Hengstler, J. G.; Jenkins, B.; Karnebeek, K. et al.; Kelly, D. A.; Koot, B. G.; Koulman, A.; Meierhofer, D.; Snowden, S. G.; van Mourik, I.; Vreugdenhil, A.; Wiegand, S.; Mann, J. P.: Variants in MARC1 and HSD17B13 reduce severity of NAFLD in children, perturb phospholipid metabolism, and suppress fibrotic pathways. medRxiv (Preprint Server for Health Sciences) (2020)

Witt, N.; Andreotti, S.; Busch, A.; Neubert, K.; Reinert, K.; Tomaso, H.; Meierhofer, D.: Rapid and Culture Free Identification of Francisella in Hare Carcasses by High-Resolution Tandem Mass Spectrometry Proteotyping. Frontiers in Microbiology 11, 11:636 (2020)

Berndt, N.; Kolbe, E.; Gajowski, R.; Eckstein, J.; Ott, F.; Meierhofer, D.; Holzhütter, H. G.; Matz‐Soja, M.: Functional consequences of metabolic zonation in murine livers: New insights for an old story. Hepatology (accepted)

Holzhütter, H.-G.; Wuensch, T.; Gajowski, R.; Berndt, N.; Bulik, S.; Meierhofer, D.; Stockmann, M.: A novel variant of the 13C-methacetin liver function breath test that eliminates the confounding effect of individual differences in sytemic CO2 kinetics. Archives of Toxicology 94 (2), pp. 401 - 415 (2020)

Kolbe, E.; Aleithe, S.; Rennert, C.; Spormann, L.; Ott, F.; Meierhofer, D.; Gajowski, R.; Stöpel, C.; Hoehme, S.; Kücken, M. et al.; Brusch, L.; Seifert, M.; von Schoenfels, W.; Schafmayer, C.; Brosch, M.; Hoffmann, U.; Damm, G.; Seehofer, D.; Hampe, J.; Gebhardt, R.; Matz-Soja, M.: Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human. Cell Reports 29 (13), e7, pp. 4553 - 4567 (2019)