Publications of Helene Kretzmer

Biran, A.; Yin, S.; Kretzmer, H.; ten Hacken, E.; Parvin, S.; Lucas, F.; Uduman, M.; Gutierrez, C.; Dangle, N. ....; Meissner, A. et al.; Wu, C. J.: Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia. Cancer Research 81 (24), pp. 6117 - 6130 (2021)

Andergassen, D.; Smith, Z. D.; Kretzmer, H.; Rinn, J. L.; Meissner, A.: Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages. Developmental Cell 56 (21), pp. 2995 - 3005 (2021)

Hetzel, S.; Gießelmann, P.; Reinert, K.; Meissner, A.; Kretzmer, H.: RLM: Fast and simplified extraction of Read-Level Methylation metrics from bisulfite sequencing data. Bioinformatics 37 (21), pp. 3934 - 3935 (2021)

Wu, H.-J.; Landshammer, A.; Stamenova, E. K.; Bolondi, A.; Kretzmer, H.; Meissner, A.; Michor, F.: Topological isolation of developmental regulators in mammalian genomes. Nature Communications 12, 4897 (2021)

Haggerty, C.; Kretzmer, H.; Riemenschneider, C.; Sampath Kumar, A.; Mattei, A. L.; Bailly, N.; Gottfreund, J.; Giesselmann, P.; Weigert, R.; Brändl, B. et al.; Giehr, P.; Buschow, R.; Galonska, C.; von Meyenn, F.; Pappalardi, M. B.; McCabe, M. T.; Wittler, L.; Giesecke-Thiel, C.; Mielke, T.; Meierhofer, D.; Timmermann, B.; Müller, F.-J.; Walter, J.; Meissner, A.: Dnmt1 has de novo activity targeted to transposable elements. Nature Structural and Molecular Biology 28 (7), pp. 594 - 603 (2021)

Bolondi, A.; Haut, L.; Gassaloglu, S. I.; Burton, P.; Kretzmer, H.; Buschow, R.; Meissner, A.; Herrmann, B. G.; Veenvliet, J. V.: Generation of Mouse Pluripotent Stem Cell-derived Trunk-like Structures: An in vitro Model of Post-implantation Embryogenesis. Bio-protocol 11 (11), e4042 (2021)

Hübschmann, D.; Kleinheinz, K.; Wagener, R.; Bernhart, S. H.; López, C.; Toprak, U. H.; Sungalee, S.; Ishaque, N.; Kretzmer, H.; Kreuz, M. et al.; Waszak, S. M.; Paramasivam, N.; Ammerpohl, O.; Aukema, S. M.; Beekman, R.; Bergmann, A. K.; Bieg, M.; Binder, H.; Borkhardt, A.; Borst, C.; Brors, B.; Bruns, P.; de Santa Pau, E. C.; Claviez, A.; Doose, G.; Haake, A.; Karsch, D.; Haas, S.; Hansmann, M.-L.; Hoell, J. I.; Hovestadt, V.; Huang, B.; Hummel, M.; Jäger-Schmidt, C.; Kerssemakers, J. N. A.; Korbel, J. O.; Kube, D.; Lawerenz, C.; Lenze, D.; Martens, J. H. A.; Ott, G.; Radlwimmer, B.; Reisinger, E.; Richter, J.; Rico, D.; Rosenstiel, P.; Rosenwald, A.; Schillhabel, M.; Stilgenbauer, S.; Stadler, P. F.; Martín-Subero, J. I.; Szczepanowski, M.; Warsow, G.; Weniger, M. A.; Zapatka, M.; Valencia, A.; Stunnenberg, H. G.; Lichter, P.; Möller, P.; Loeffler, M.; Eils, R.; Klapper, W.; Hoffmann, S.; Trümper, L.; ICGC MMML-Seq consortium; ICGC DE-Mining consortium; BLUEPRINT consortium; Küppers, R.; Schlesner, M.; Siebert, R.: Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 35 (7), pp. 2002 - 2016 (2021)

Kretzmer, H.; Biran, A.; Purroy, N.; Lemvigh, C. K.; Clement, K.; Gruber, M.; Gu, H.; Rassenti, L.; Mohammad, A. W.; Lesnick, C. et al.; Slager, S. L.; Braggio, E.; Shanafelt, T. D.; Kay, N. E.; Fernandes, S. M.; Brown, J. R.; Wang, L.; Li, S.; Livak, K. J.; Neuberg, D. S.; Klages, S.; Timmermann, B.; Kipps, T. J.; Campo, E.; Gnirke, A.; Wu, C. J.; Meissner, A.: Pre-neoplastic alterations define CLL DNA methylome and persist through disease progression and therapy. Blood Cancer Discovery 2 (1), pp. 54 - 69 (2021)

Veenvliet, J. V.; Bolondi, A.; Kretzmer, H.; Haut, L.; Scholze-Wittler, M.; Schifferl, D.; Koch, F.; Guignard, L.; Sampath Kumar, A.; Pustet, M. et al.; Heimann, S.; Buschow, R.; Wittler, L.; Timmermann, B.; Meissner, A.; Herrmann, B. G.: Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites. Science 370 (6522), eaba4937 (2020)

Riege, K.; Kretzmer, H.; Sahm, A.; McDade, S. S.; Hoffmann, S.; Fischer, M.: Dissecting the DNA binding landscape and gene regulatory network of p63 and p53. eLife 9, e63266 (2020)

Grosswendt, S.; Kretzmer, H.; Smith, Z. D.; Sampath Kumar, A.; Hetzel, S.; Wittler, L.; Klages, S.; Timmermann, B.; Mukherji, S.; Meissner, A.: Epigenetic regulator function through mouse gastrulation. Nature 584, pp. 102 - 108 (2020)

Gießelmann, P.; Brändl, B.; Raimondeau, E.; Bowen, R.; Rohrandt, C.; Tandon, R.; Kretzmer, H.; Assum, G.; Galonska, C.; Siebert, R. et al.; Ammerpohl, O.; Heron, A.; Schneider, S. A.; Ladewig, J.; Koch, P.; Schuldt, B. M.; Graham, J. E.; Meissner, A.; Müller, F.-J.: Analysis of short tandem repeat expansions and their methylation state with nanopore sequencing. Nature Biotechnology 37 (12), pp. 1478 - 1481 (2019)

Biran, A.; Kretzmer, H.; Yin, S.; Billington, L.; Regis, F. F.; Mohammad, A. W.; Gnirke, A.; Neuberg, D. S.; Carrasco, R. D.; Meissner, A. et al.; Wu, C. J.: Deciphering the Role of Locally Disordered DNA Methylation on CLL Development In Vivo. Blood 134 (Suppl. 1), p. 1737 - 1737 (2019)

Giesselmann, P.; Hetzel, S.; Müller, F.-J.; Meissner, A.; Kretzmer, H.: Nanopype: A modular and scalable nanopore data processing pipeline. Bioinformatics 35 (22), pp. 4770 - 4772 (2019)

Chan, M. M.; Smith, Z. D.; Grosswendt, S.; Kretzmer, H.; Norman, T. M.; Adamson, B.; Jost, M.; Quinn, J. J.; Yang, D.; Jones, M. G. et al.; Khodaverdian, A.; Nir, Y.; Meissner, A.; Weissman, J. S.: Molecular recording of mammalian Embryogenesis. Nature 570 (7759), pp. 77 - 82 (2019)

Knisbacher, B. A.; Lin, Z.; Hahn, C. K.; Nadeu, F.; Duran-Ferrer, M.; Stevenson, K. E.; Tausch, E.; Barbera-Mourelle, A.; Dunford, A.; Anand, S. et al.; Delgado, J.; Hess, J. M.; Taylor-Weiner, A.; Kretzmer, H.; Bousquets Muñoz, P.; Shaughnessy, C. J.; Fernandes, S. M.; Sivina, M.; Rassenti, L. Z.; Meissner, A.; Wiestner, A. ....; Getz, G.: The CLL-1100 Project: Towards Complete Genomic Characterization and Improved Prognostics for CLL. 62nd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH) (Virtual meeting), December 05, 2020 - December 08, 2020. Blood 136, S3, (2020)

Kubelt , C.; Brändl , B.; van Bömmel , A.; Rohrandt, C.; Wang, G.; Evers , M.; Kolkenbrock , S.; Wong, D.; Danso, D.; Maicher, A. et al.; Friedrichsen , S.; Proescholdt , M.; Riemenschneider , M.; Jetzek, U.; Meissner, A.; Yip , S.; Kretzmer, H.; Synowitz, M.; Müller, F.-J.: INTRAEPIGLIOM - RAPID SEQUENCING-BASED DIAGNOSIS OF BRAIN TUMORS. 27th Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO), Tampa, FL, November 16, 2022 - November 20, 2022. Neuro-Oncology: official journal of the World Federation of Neuro-Oncology 24, Suppl. 7 Ed., pp. 160 - 161 (2022)

Hübner, P.: Association Plots – A Method to Detect Tissue-Specific Regulatory Patterns? Master (2024)

Bolondi, A.; Kretzmer, H.; Meissner, A.: Single-cell technologies: a new lens into epigenetic regulation in development. Current Opinion in Genetics & Development 76, 101947 (2022)