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Journal Article (9)

  1. 1.
    Journal Article
    Witte, F.; Chan, D.; Economides, A. N.; Mundlos, S.; Stricker, S.: Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region. Proceedings of the National Academy of Sciences U S A 107 (32), pp. 14211 - 14216 (2010)
  2. 2.
    Journal Article
    Witte, F.; Bernatik, O.; Kirchner, K.; Masek, J.; Mahl, A.; Krejci, P.; Mundlos, S.; Schambony, A.; Bryja, V.; Stricker, S.: Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2. The FASEB Journal 24 (7), pp. 2417 - 2426 (2010)
  3. 3.
    Journal Article
    van Wijk, N. V.; Witte, F.; Feike, A. C.; Schambony, A.; Birchmeier, W.; Mundlos, S.; Stricker, S.: The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling. Biochemical and Biophysical Research Communications 390 (2), pp. 211 - 216 (2009)
  4. 4.
    Journal Article
    Schwarzer, W.; Witte, F.; Rajab, A.; Mundlos, S.; Stricker, S.: A gradient of ROR2 protein stability and membrane localization confers brachydactyly type B or Robinow syndrome phenotypes. Human Molecular Genetics 18 (21), pp. 4013 - 4021 (2009)
  5. 5.
    Journal Article
    Gao, B.; Hu, J.; Stricker, S.; Cheung, M.; Ma, G.; Law, K. F.; Witte, F.; Briscoe, J.; Mundlos, S.; He, L. et al.; Cheah, K. S. E.; Chan, D.: A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range. Nature 458 (7242), pp. 1196 - 1200 (2009)
  6. 6.
    Journal Article
    Witte, F.; Dokas, J.; Neuendorf, F.; Mundlos, S.; Stricker, S.: Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation. Gene Expression Patterns 9 (4), pp. 215 - 223 (2009)
  7. 7.
    Journal Article
    Kuss, P.; Villavicencio-Lorini, P.; Witte, F.; Klose, J.; Albrecht, A. N.; Seemann, P.; Hecht, J.; Mundlos, S.: Mutant Hoxd13 induces extra digits in a mouse model of synpolydactyly directly and by decreasing retinoic acid synthesis. Journal of Clinical Investigation 119 (1), pp. 146 - 156 (2009)
  8. 8.
    Journal Article
    Raz, R.; Stricker, S.; Elizabetta Gazzerro, E.; Clor, J. L.; Witte, F.; Nistala, H.; Zabski, S.; Pereira, R. C.; Stadmeyer, L.; Wang, X. et al.; Gowen, L.; Sleeman, M. W.; Yancopoulos, G. D.; Canalis, E.; Mundlos, S.; Valenzuela, D. M. V.; Economides, A. N.: The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome. Development 135 (9), pp. 1713 - 1723 (2008)
  9. 9.
    Journal Article
    Stricker, S.; Van Wijk, N. V.; Witte, F.; Brieske, N.; Seidel, K.; Mundlos, S.: Cloning and expression pattern of chicken Ror2 and functional characterization of truncating mutations in Brachydactyly type B and Robinow syndrome. Developmental Dynamics 235 (12), pp. 3456 - 3465 (2006)

Thesis - PhD (1)

  1. 10.
    Thesis - PhD
    Witte, F.: Analyse der Ror2-Funktion in vivo und in vitro: die Ror2W749X-Maus als Modell für humane Brachydaktylie Typ B. Dissertation, Freie Universität, Berlin (2009)
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