Mathematical models demonstrate the integration of information through cellular signal transduction pathways

Research report (imported) 2007 - Max Planck Institute for Molecular Genetics

Authors
Klipp, Edda
Departments
Otto-Warburg-Laboratorium - Computational Systems Biology (Dr. Edda Klipp)
MPI für molekulare Genetik, Berlin
Summary
Molecular approaches reveal components and mechanisms of cellular stress sensing and adaptation. In addition, mathematical modeling has proven to foster the understanding of some basic principles of signal transduction and signal processing as well as of sensitivity and robustness of information perception and cellular response. Main modeling principles are exemplified here for a model organism, the yeast Saccharomyces cerevisiae.

For the full text, see the German version.

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