Lab News

In a new study published in Genes & Development, researchers from the labs of Stefan Mundlos (Max Planck Institute for Molecular Genetics and Charité, Berlin) and Lila Allou (MRC Laboratory of Medical Sciences, London) demonstrate how different regulatory genetic elements coordinate the temporal activity of a key developmental gene. Their findings likely explain subtle differences seen in patients with congenital limb malformations, for which the underlying disease mechanisms often remain unknown. more

In our “meet the first author” interview series, we take a look behind the scenes of science. more

New research findings from a collaboration between the labs of Stefan Mundlos, Dario G. Lupiáñez, and Francisca M. Real show how genetic programs were reused during the evolution of mammalian flight. more

A new study by Stefan Mundlos's lab reveals how viral-like particles cause a developmental malformation. more

Startup will use funds to fine-tune their AI models for diagnostics and biomarker discovery more

Hunting for disease clues in the dark matter of our DNA more

Layers of gene control allow DNA to flexibly add new information more

The genomics of evolution: how bats learned to fly more

Researcher receives Mendel Medal for findings on gene regulation and genetic skeletal malformations more

Congenital malformation caused by a so far unknown disease mechanism more

New animal model for GPI anchor deficiencies more

Duplications and inversions of DNA segments lead to the masculinization of female moles more

Hi-C method improves detection of breaks and rearrangements in the genome more

Berlin researchers discover new pathomechanism of hereditary diseases in cell condensates more

Stefan Mundlos, from the Max Planck Institute for Molecular Genetics, explains why there will be no designer babies in the near future more

Formation of the 3D structure and specific interaction between genes and enhancers represent independent layers of gene regulation more

Crowdfunded project reveals genome of internet celebrity cat more

Scientists at the Max Planck Institute for Molecular Genetics describe tissue-specific formation of architectural stripes driven by enhancer activity and CTCF elements more

Dynamic changes in the structure of chromatin controls the development of arms and legs more

Scientists from Berlin and Naples develop methods for predictions about the three-dimensional structure of DNA more