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21 (11), pp. 1449 - 1461 (2019)
Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo. Nature Cell Biology 102.
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Differential regulation of OCT4 targets facilitates reacquisition of pluripotency. Nature Communications 103.
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146 (19), dev174722 (2019)
Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression. Development 104.
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Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. Nature Communications 105.
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24 (7), pp. 1027 - 1039 (2019)
Genetics of intellectual disability in consanguineous families. Molecular Psychiatry 106.
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35 (22), pp. 4770 - 4772 (2019)
Nanopype: A modular and scalable nanopore data processing pipeline. Bioinformatics 107.
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74 (5), pp. 951 - 965 (2019)
Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Molecular Cell 108.
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570 (7759), pp. 77 - 82 (2019)
Molecular recording of mammalian Embryogenesis. Nature 109.
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Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia. Nature 110.
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10 (1), 1874 (2019)
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL. Nature Communications 111.
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Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations. Nature Cell Biology 112.
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28 (4), pp. 615 - 627 (2019)
Sensory neuropathy-causing mutations in ATL3 affect ER-mitochondria contact sites and impair axonal mitochondrial distribution. Human Molecular Genetics 113.
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35 (2), pp. 330 - 332 (2019)
KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. Cancer Cell 114.
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22 (1), pp. 37 - 46 (2019)
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains. Nature Neuroscience 115.
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Generation of an iPSC line of a patient with Angelman syndrome due to an imprinting defect. Stem Cell Research 116.
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Generation of two human isogenic iPSC lines from fetal dermal fibroblasts. Stem Cell Research 117.
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Targets and genomic constraints of ectopic Dnmt3b expression. eLife 118.
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145 (22), pii: dev168617 (2018)
Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons. Development 119.
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563 (7731), p. 325 (2018)
Paying PIs from grants blocks talent and diversity. Nature 120.
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Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2. Nucleic Acids Research (London)