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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. Cancer Cell 82.
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Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains. Nature Neuroscience 83.
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33, S. 20 - 24 (2018)
Generation of an iPSC line of a patient with Angelman syndrome due to an imprinting defect. Stem Cell Research 84.
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33, S. 120 - 124 (2018)
Generation of two human isogenic iPSC lines from fetal dermal fibroblasts. Stem Cell Research 85.
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Targets and genomic constraints of ectopic Dnmt3b expression. eLife 86.
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145 (22), pii: dev168617 (2018)
Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons. Development 87.
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Paying PIs from grants blocks talent and diversity. Nature 88.
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46 (17), S. 9044 - 9056 (2018)
Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2. Nucleic Acids Research (London) 89.
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7 (3), e3, S. 258 - 268 (2018)
Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome. Cell Systems 90.
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15 (9), S. 732 - 740 (2018)
Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells. Nature methods 91.
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23 (2), e5, S. 289 - 305 (2018)
Prospective Isolation of Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming. Cell Stem Cell 92.
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Coactivator condensation at super-enhancers links phase separation and gene control. Science (6400), eaar3958 (2018)
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174 (2), e19, S. 391 - 405 (2018)
A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity. Cell 94.
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Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. Cell Reports 95.
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9 (1), 1925 (2018)
Assessment of Established Techniques to Determine Developmental and Malignant Potential of Human Pluripotent Stem Cells. Nature Communications 96.
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10 (5), S. 1537 - 1550 (2018)
X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs. Stem Cell Reports 97.
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173 (3), e8, S. 624 - 633 (2018)
Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade. Cell 98.
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23 (2), S. 349 - 360 (2018)
Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism. Cell Reports 99.
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22 (4), e7, S. 575 - 588 (2018)
A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. Cell Stem Cell 100.
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102 (4), S. 557 - 573 (2018)
Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood. American Journal of Human Genetics