Publications of Lars Wittler
All genres
Journal Article (49)
1.
Journal Article
623 (7988), pp. 772 - 781 (2023)
Single-cell, whole-embryo phenotyping of mammalian developmental disorders. Nature 2.
Journal Article
150 (22), dev202111 (2023)
Genome-wide identification of notochord enhancers comprising the regulatory landscape of the Brachyury (T) locus in mouse. Development 3.
Journal Article
25, pp. 1704 - 1715 (2023)
GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of long-range enhancers. Nature Cell Biology 4.
Journal Article
55 (7), pp. 1176 - 1185 (2023)
Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis. Nature Genetics 5.
Journal Article
BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage. Development, dev.201450 (2023)
6.
Journal Article
14, 1475 (2023)
Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve Split-Hand/Foot Malformation type 3. Nature Communications 7.
Journal Article
150 (17), dev201562 (2023)
Induction of kidney-related gene programs through co-option of SALL1 in mole ovotestes. Development 8.
Journal Article
Co-option of the transcription factor SALL1 in mole ovotestis formation. bioRxiv, 514220 (2022)
9.
Journal Article
185 (20), pp. 3689 - 3704 (2022)
Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes. Cell 10.
Journal Article
54, pp. 1238 - 1247 (2022)
Hijacking of transcriptional condensates by endogenous retroviruses. Nature Genetics 11.
Journal Article
12, 3100 (2022)
Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction. Scientific Reports 12.
Journal Article
25 (1), 103556 (2022)
Emergence and patterning dynamics of mouse-definitive endoderm. iScience 13.
Journal Article
148 (23), dev200059 (2021)
A 37 kb region upstream of brachyury comprising a notochord enhancer is essential for notochord and tail development. Development 14.
Journal Article
28 (7), pp. 594 - 603 (2021)
Dnmt1 has de novo activity targeted to transposable elements. Nature Structural and Molecular Biology 15.
Journal Article
Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator. Nature (2021)
16.
Journal Article
118 (2), e2014481118 (2021)
A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions. Proceedings of the National Academy of Sciences of the United States of America 17.
Journal Article
370 (6522), eaba4937 (2020)
Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites. Science 18.
Journal Article
370 (6513), pp. 208 - 214 (2020)
The mole genome reveals regulatory rearrangements associated with adaptive intersexuality. Science 19.
Journal Article
8, 567 (2020)
SLC20A1 Is Involved in Urinary Tract and Urorectal Development. Frontiers in Cell and Developmental Biology 20.
Journal Article
584, pp. 102 - 108 (2020)
Epigenetic regulator function through mouse gastrulation. Nature