Publications of Markus Ralser

Hovestadt , V.; Jones , D.; Picelli , S.; Wang , W.; Kool , M.; Northcott , P. A.; Sultan, M.; Stachurski , K.; Ryzhova , M.; Warnatz, H. J. et al.; Ralser, M.; Brun , S.; Bunt , J.; Jäger , N.; Kleinheinz , K.; Erkek , S.; Weber , U. D.; Bartholomae, C. C.; von Kalle , C.; Lawerenz , C.; Eils , J.; Koster , J.; Versteeg , R.; Milde , T.; Witt , O.; Schmidt , S.; Wolf , S.; Pietsch , T.; Rutkowski, S.; Scheurlen , W.; Taylor , M. B.; Brors , B.; Felsberg , J.; Reifenberger , G.; Borkhardt , A.; Lehrach, H.; Wechsler-Reya , R.; Eils , R.; Yaspo, M.-L.; Landgraf , P.; Korshunov , A.; Zapatka , M.; Radlwimmer , B.; Pfister , S. M.; Lichter , P.: Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing. Nature 26 (510), pp. 537 - 541 (2014)

Tosato, V.; Grüning, N.-M.; Breitenbach, M.; Arnak, R.; Ralser, M.; Bruschi, C. V.: Warburg effect and translocation-induced genomic instability: two yeast models for cancer cells. Frontiers in Oncology 2, 212 (2013)

Jones, D. T.; Hutter, B.; Jager, N.; Korshunov, A.; Kool, M.; Warnatz, H. J.; Zichner, T.; Lambert, S. R.; Ryzhova, M.; Quang, D. A. et al.; Fontebasso, A. M.; Stutz, A. M.; Hutter, S.; Zuckermann, M.; Sturm, D.; Gronych, J.; Lasitschka, B.; Schmidt, S.; Seker-Cin, H.; Witt, H.; Sultan, M.; Ralser, M.; Northcott, P. A.; Hovestadt, V.; Bender, S.; Pfaff, E.; Stark, S.; Faury, D.; Schwartzentruber, J.; Majewski, J.; Weber, U. D.; Zapatka, M.; Raeder, B.; Schlesner, M.; Worth, C. L.; Bartholomae, C. C.; von Kalle, C.; Imbusch, C. D.; Radomski, S.; Lawerenz, C.; van Sluis, P.; Koster, J.; Volckmann, R.; Versteeg, R.; Lehrach, H.; Monoranu, C.; Winkler, B.; Unterberg, A.; Herold-Mende, C.; Milde, T.; Kulozik, A. E.; Ebinger, M.; Schuhmann, M. U.; Cho, Y. J.; Pomeroy, S. L.; von Deimling, A.; Witt, O.; Taylor, M. D.; Wolf, S.; Karajannis, M. A.; Eberhart, C. G.; Scheurlen, W.; Hasselblatt, M.; Ligon, K. L.; Kieran, M. W.; Korbel, J. O.; Yaspo, M. L.; Brors, B.; Felsberg, J.; Reifenberger, G.; Collins, V. P.; Jabado, N.; Eils, R.; Lichter, P.; Pfister, S. M.: Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nature Genetics 45 (8), pp. 927 - 32 (2013)

Vowinckel, J.; Stahlberg, S.; Paulmann, N.; Bluemlein, K.; Grohmann, M.; Ralser, M.; Walther, D. J.: Histaminylation of glutamine residues is a novel posttranslational modification implicated in G-protein signaling. FEBS Letters 586 (21), pp. 3819 - 3824 (2012)

Bluemlein, K.; Glückmann, M.; Grüning, N.-M.; Feichtinger, R.; Krueger, A.; Wamelink6,, M.; Lehrach, H.; Tate, S.; Neureiter, D.; Kofler, B. et al.; Ralser, M.: Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis. Oncotarget 3 (11), p. 1356 - 1356 (2012)

Bluemlein, K.; Glückmann, M.; Grüning, N.-M.; Feichtinger, R.; Krüger, A.; Wamelink, M.; Lehrach, H.; Tate, S.; Neureiter, D.; Kofler, B. et al.; Ralser, M.: Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis. Oncotarget 3 (11), pp. 1356 - 1369 (2012)

Ralser, M.; Kuhl, H.; Ralser, M.; Werber, M.; Lehrach, H.; Breitenbach, M.; Timmermann, B.: The Saccharomyces cerevisiae W303-K6001 cross-platform genome sequence: insights into ancestry and physiology of a laboratory mutt. Open Biology 2 (8), 120093 (2012)

Breitenbach, M.; Laun, P.; Dickinson, J. R.; Klocker, A.; Rinnerthaler, M.; Dawes, I. W.; Aung-Htut, M. T.; Breitenbach-Koller, L.; Caballero, A.; Nystrom, T. et al.; Buttner, S.; Eisenberg, T.; Madeo, F.; Ralser, M.: The role of mitochondria in the aging processes of yeast. Sub-Cellular Biochemistry 57, pp. 55 - 78 (2012)

Habermann, K.; Mirgorodskaya, E.; Gobom, J.; Lehmann, V.; Müller, H.; Blümlein, K.; Deery, M. J.; Czogiel, I.; Erdmann, C.; Ralser, M. et al.; von Kries, J. P.; Lange, B. M. H.: Functional analysis of centrosomal kinase substrates in Drosophila melanogaster reveals a new function of the nuclear envelope component otefin in cell cycle progression. Molecular and Cellular Biology (Washington, DC) 32 (17), pp. 3554 - 3569 (2012)

Ralser, M.; Michel, S.; Breitenbach, M.: Sirtuins as regulators of the yeast metabolic network. Frontiers in Pharmacology 3, 3:32 (2012)

Hallen, L.; Klein, H.; Stoschek, C.; Wehrmeyer, S.; Nonhoff, U.; Ralser, M.; Wilde, J.; Rohr, C.; Schweiger, M. R.; Zatloukal, K. et al.; Vingron, M.; Lehrach, H.; Konthur, Z.; Krobitsch, S.: The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2. Human Molecular Genetics 20, pp. 104 - 114 (2011)

Bluemlein, K.; Gruning, N. M.; Feichtinger, R. G.; Lehrach, H.; Kofler, B.; Ralser, M.: No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis. Oncotarget 2 (5), pp. 393 - 400 (2011)

Bluemlein, K.; Ralser, M.: Monitoring protein expression in whole-cell extracts by targeted label- and standard-free LC-MS/MS. Nature Protocols 6 (6), pp. 859 - 69 (2011)

Gruning, N. M.; Ralser, M.: Cancer: Sacrifice for survival. Nature 480 (7376), pp. 190 - 1 (2011)

Gruning, N. M.; Rinnerthaler, M.; Bluemlein, K.; Mulleder, M.; Wamelink, M. M.; Lehrach, H.; Jakobs, C.; Breitenbach, M.; Ralser, M.: Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells. Cell Metabolism 14 (3), pp. 415 - 27 (2011)

Kruger, A.; Gruning, N. M.; Wamelink, M. M.; Kerick, M.; Kirpy, A.; Parkhomchuk, D.; Bluemlein, K.; Schweiger, M. R.; Soldatov, A.; Lehrach, H. et al.; Jakobs, C.; Ralser, M.: The pentose phosphate pathway is a metabolic redox sensor and regulates transcription during the antioxidant response. Antioxidants & Redox Signaling 15 (2), pp. 311 - 24 (2011)

Kruger, A.; Ralser, M.: ATM is a redox sensor linking genome stability and carbon metabolism. Science Signaling 4 (167), p. pe17 (2011)

Prigione, A.; Lichtner, B.; Kuhl, H.; Struys, E. A.; Wamelink, M.; Lehrach, H.; Ralser, M.; Timmermann, B.; Adjaye, J.: Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming. Stem Cells 29 (9), pp. 1338 - 48 (2011)

Timmermann, B.; Jarolim, S.; Russmayer, H.; Kerick, M.; Michel, S.; Krüger, A.; Bluemlein, K.; Laun, P.; Grillari, J.; Lehrach, H. et al.; Breitenbach, M.; Ralser, M.: A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging. Aging (Albany NY) 2 (8), pp. 475 - 486 (2010)

Wamelink, M. M.; Gruning, N. M.; Jansen, E. E.; Bluemlein, K.; Lehrach, H.; Jakobs, C.; Ralser, M.: The difference between rare and exceptionally rare: molecular characterization of ribose 5-phosphate isomerase deficiency. Journal of Molecular Medicine 88 (9), pp. 931 - 939 (2010)