Suchergebnisse

Müller, J. M.; Altendorfer, E.; Freier, S.; Moos, K.; Mayer, A.; Tresch, A.: Halfpipe: a tool for analyzing metabolic labeling RNA-seq data to quantify RNA half-lives. NAR: genomics and bioinformatics 7 (1), Article lqaf006 (2025)

Turewicz, M.; Skagen, C.; Hartwig, S.; Majda, S.; Thedinga, K.; Herwig, R.; Binsch , C.; Altenhofen, D.; Ouwens, D. M.; Förster, P. M. et al.; Wachtmeister, T.; Köhrer, K.; Stermann, T.; Chadt, A.; Lehr, S.; Marschall , T.; Thoresen, G. H.; Al-Hasani, H.: Temporal phosphoproteomics reveals circuitry of phased propagation in insulin signaling. Nature Communications 16 (1), Article 1570 (2025)

Martina, L.; Malszycki, M.; Aktas, T.: Distinct states of Nuclear Speckles emerge as new predictors of cancer prognosis. Cancer Research 85 (8), S. 1352 - 1353 (2025)

Brumm, A. S.; McCarthy, A.; Gerri, C.; Fallesen, T.; Woods, L.; McMahon, R.; Papathanasiou, A.; Elder, K.; Snell, P.; Christie, L. et al.; Garcia, P.; Shaikly, V.; Taranissi, M.; Serhal, P.; Odia, R. A.; Vasilic, M.; Osnato, A.; Rugg-Gunn, P. J.; Vallier, L.; Hill, C. S.; Niakan, K. K.: Initiation and maintenance of the pluripotent epiblast in pre-implantation human development is independent of NODAL signaling. Developmental Cell 60 (2), S. 174 - 185 (2025)

Lauer, S. M.; Gasse, J.; Krizsan, A.; Reepmeyer, M.; Sprink, T.; Nikolay, R.; Spahn, C. M. T.; Hoffmann, R.: The proline-rich antimicrobial peptide Api137 disrupts large ribosomal subunit assembly and induces misfolding. Nature Communications 16 (1), Article 567 (2025)

Lazaro-Navarro, J.; Alcon, C.; Dorel, M.; Alasfar, L.; Bastian, L.; Baldus, C.; Astrahantseff, K.; Yaspo, M.-L.; Montero, J.; Eckert, C.: Inhibiting H3K27 Demethylases Downregulates CREB-CREBBP, Overcoming Resistance in Relapsed Acute Lymphoblastic Leukemia. Cancer Medicine 14 (1), S. 1 - 7 (2025)

Hiepen, C.; Benamar, M.; Barrasa-Fano, J.; Condor, M.; Ilhan, M.; Münch, J.; Hastar, N.; Kerkhoff, Y.; Harms, G. S.; Mielke, T. et al.; Koenig, B.; Block, S.; Rocks, O.; Abdelilah-Seyfried, S.; Van Oosterwyck , H.; Knaus, P.: Endothelial tip-cell position, filopodia formation and biomechanics require BMPR2 expression and signaling. Communications Biology 8 (1), Article 21 (2025)

Wiechert, F.; Unbehaun, A.; Sprink, T.; Seibel, H.; Bürger, J.; Loerke, J.; Mielke, T.; Diebolder , C. A.; Schacherl , M.; Spahn, C. M. T.: Visualizing the modification landscape of the human 60S ribosomal subunit at close to atomic resolution. Nucleic Acids Research 53 (1), Article gkae1191 (2025)

McIntyre, A. B. R.; Tschan, A. B.; Meyer, K.; Walser, S.; Rai, A. K.; Fujita, K.; Pelkmans, L.: Phosphorylation of a nuclear condensate regulates cohesion and mRNA retention. Nature Communications 16 (1), Article 390 (2025)

Lützkendorf, J.; Matkovic-Rachid, T.; Liu, S.; Götz, T.; Gao, L.; Turrel, O.; Maglione, M.; Grieger, M.; Putignano, S.; Ramesh, N. et al.; Ghelani, T.; Neumann, A.; Gimber, N.; Schmoranzer, J.; Stawrakakis, A.; Brence, B.; Baum, D.; Ludwig, K.; Heine, M.; Mielke, T.; Liu, F.; Walter, A. M.; Wahl, M. C.; Sigrist, S. J.: Blobby is a synaptic active zone assembly protein required for memory in Drosophila. Nature Communications 16 (1), Article 271 (2025)

Glaser, S.; Kretzmer, H.; Kolassa, I. T.; Schlesner, M.; Fischer, A.; Fenske, I.; Siebert, R.; Ammerpohl , O.: Navigating Illumina DNA methylation data: biology versus technical artefacts. NAR: genomics and bioinformatics 6 (4), Article lqae181 (2024)

Kopp, J.; Jahn, D.; Vogt, G.; Psoma, A.; Ratto, E.; Morelle, W.; Stelzer, N.; Hausser , I.; Hoffmann, A.; de Los Santos, M. R. et al.; Koch, L. A.; Fischer-Zirnsak, B.; Thiel, C.; Palm, W.; Meierhofer, D.; van den Bogaart, G.; Foulquie, F.; Meinhardt, A.; Kornak, U.: Golgi pH elevation due to loss of V-ATPase subunit V0a2 function correlates with tissue-specific glycosylation changes and globozoospermia. Cellular and Molecular Life Sciences 82 (1), Article 4 (2024)

Hasenbein, T. P.; Hoelzl, S.; Smith, Z. D.; Gerhardinger, C.; Gonner, M. O. C.; Aguilar-Pimentel, A.; Amarie, O. V.; Becker, L.; Calzada-Wack, J.; Dragano, N. R. V. et al.; da Silva-Buttkus, P.; Garrett, L.; Hölter, S. M.; Kraiger, M.; Östereicher, M. A.; Rathkolb, B.; Sanz-Moreno, A.; Spielmann, N.; Wurst, W.; Gailus-Durner, V.; Fuchs, H.; Hrabě de Angelis, M.; Meissner, A.; Engelhardt, S.; Rinn, J. L.; Andergassen, D.: X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes. Nature Communications 15 (1), Article 10631 (2024)

Reissland, M.; Hartmann, O.; Tauch, S. e. a.; Diefenbacher, M. E.: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer. Oncogene 43 (50), S. 3645 - 3659 (2024)

Aldrovandi, S.; Fajardo Castro, J.; Ullrich, K.; Karger, A.; Luria, V.; Tautz, D.: Expression of random sequences and de novo evolved genes from the mouse in human cells reveals functional diversity and specificity. Genome Biology and Evolution 16 (12), Article evae175 (2024)

Chan, W. L.; Bucher, C. H.; Goldes, J.; Ma, A. C.; Steiner, M.; Willie, B. M.; Mundlos, S.; Kornak, U.: Targeting TGF-β signaling, oxidative stress, and cellular senescence rescues osteoporosis in gerodermia osteodysplastica. Aging Cell 23 (12), Article e14322 (2024)

Szalay , M.-F.; Majchrzycka, B.; Jerković, I.; Cavalli, G.; Ibrahim, D. M.: Evolution and function of chromatin domains across the tree of life. Nature Structural & Molecular Biology 31 (12), S. 1824 - 1837 (2024)

Longo , G. M. C.; Sayols, S.; Stefanova, M. E.; Xie, T.; Elsayed, W.; Panagi , A.; Stavridou, A. I.; Petrosino, G.; Ing-Simmons, E.; Melo, U. S. et al.; Gothe, H. J.; Vaquerizas, J. M.; Kotini , A. G.; Papantonis, A.; Mundlos, S.; Roukos , V.: Type II topoisomerases shape multi-scale 3D chromatin folding in regions of positive supercoils. Molecular Cell 84 (22), S. 4267 - 4281 (2024)

Pacholewska, A.; Lienhard, M.; Brueggemann, M.; Haenel, H.; Bilalli, L.; Koenigs, A.; Hess, F.; Becker, K.; Koehrer, K.; Kaiser, J. F. et al.; Gohlke, H.; Gattermann, N.; Hallek, M.; Herling, C. D.; Koenig, J.; Grimm, C.; Herwig, R.; Zarnack, K.; Schweiger, M. R.: Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutations. Genome Research 34 (11), S. 1832 - 1848 (2024)

Bortolini Silveira, A.; Houy, A.; Ganier, O.; Özemek, B.; Vanhuele, S.; Vincent-Salomon, A.; Cassoux, N.; Mariani , P.; Pierron, G.; Leyvraz, S. et al.; Rieke, D.; Picca, A.; Bielle, F.; Yaspo, M.-L.; Rodrigues, M.; Stern, M.-H.: Base-excision repair pathway shapes 5-methylcytosine deamination signatures in pan-cancer genomes. Nature Communications 15 (1), Article 9864 (2024)