Publications of Sven Klages

Messingschlager, M.; Mackowiak, S. D.; Voelker, M. T.; Bieg, M.; Loske, J.; Chua, R. L.; Liebig, J.; Lukassen, S.; Thürmann, L.; Seegebarth, A. et al.; Twardziok, S.; Doncevic, D.; Herrmann, C.; Lorenz, S.; Klages, S.; Steinbeis, F.; Witzenrath, M.; Kurth, F.; Conrad, C.; Sander, L. E.; Ishaque, N.; Eils, R.; Lehmann , I.; Laudi, S.; Trump, S.: DNA methylation changes during acute COVID-19 are associated with long-term transcriptional dysregulation in patients' airway epithelial cells. Embo Molecular Medicine (2025)

Loske, J.; Völler , M.; Lukassen, S.; Stahl, M.; Thürmann, L.; Seegebarth, A.; Röhmel, J.; Wisniewski, S.; Lorenz, S.; Klages, S. et al.; Messingschlager, M.; Eils, R.; Lehmann, I.; Mall , M. A.; Graeber, S. Y.; Trump, S.: Pharmacological Improvement of CFTR Function Rescues Airway Epithelial Homeostasis and Host Defense in Children with Cystic Fibrosis. American Journal of Respiratory and Critical Care Medicine 209 (11), pp. 1338 - 1350 (2024)

Villanueva-Martin, G.; Acosta-Herrera, M.; Carmona, E. G.; Kerick, M.; Ortego-Centeno, N.; Callejas-Rubio, J. L.; Mages, N.; Klages, S.; Börno, S.; Timmermann, B. et al.; Bossini-Castillo, L.; Martin, J.: Non-classical circulating monocytes expressing high levels of microsomal prostaglandin E2 synthase-1 tag an aberrant IFN-response in systemic sclerosis. Journal of Autoimmunity 140, 103097 (2023)

Loske, J.; Röhmel, J.; Lukassen, S.; Stricker, S.; Magalhães, V. G.; Liebig, J.; Chua, R. L.; Thürmann, L.; Messingschlager, M.; Seegebarth, A. et al.; Timmermann, B.; Klages, S.; Ralser, M.; Sawitzki, B.; Sander, L. E.; Corman, V. M.; Conrad, C.; Laudi, S.; Binder, M.; Trump, S.; Eils, R.; Mall, M. A.; Lehmann, I.: Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children. Nature Biotechnology 40 (3), pp. 319 - 324 (2021)

Skern-Mauritzen, R.; Malde, K.; Eichner, C.; Dondrup, M.; Furmanek, T.; Besnier, F.; Komisarczuk, A. Z.; Nuhn, M.; Dalvin, S.; Edvardsen, R. B. et al.; Klages, S.; Huettel, B.; Stueber, K.; Grotmol, S.; Karlsbakk, E.; Kersey, P.; Leong, J. S.; Glover, K. A.; Reinhardt, R.; Lien, S.; Jonassen, I.; Koop, B. F.; Nilsen, F.: The salmon louse genome: Copepod features and parasitic adaptations. Genomics 113 (6), pp. 3666 - 3680 (2021)

Kuhl, H.; Frankl-Vilches, C.; Bakker, A.; Mayr, G.; Nikolaus, G.; Boerno, S. T.; Klages, S.; Timmermann, B.; Gahr, M.: An unbiased molecular approach using 3’-UTRs resolves the avian family-level tree of life. Molecular Biology and Evolution 38 (1), pp. 108 - 127 (2021)

Kretzmer, H.; Biran, A.; Purroy, N.; Lemvigh, C. K.; Clement, K.; Gruber, M.; Gu, H.; Rassenti, L.; Mohammad, A. W.; Lesnick, C. et al.; Slager, S. L.; Braggio, E.; Shanafelt, T. D.; Kay, N. E.; Fernandes, S. M.; Brown, J. R.; Wang, L.; Li, S.; Livak, K. J.; Neuberg, D. S.; Klages, S.; Timmermann, B.; Kipps, T. J.; Campo, E.; Gnirke, A.; Wu, C. J.; Meissner, A.: Pre-neoplastic alterations define CLL DNA methylome and persist through disease progression and therapy. Blood Cancer Discovery 2 (1), pp. 54 - 69 (2021)

Grosswendt, S.; Kretzmer, H.; Smith, Z. D.; Sampath Kumar, A.; Hetzel, S.; Wittler, L.; Klages, S.; Timmermann, B.; Mukherji, S.; Meissner, A.: Epigenetic regulator function through mouse gastrulation. Nature 584, pp. 102 - 108 (2020)

Gossmann, T. I.; Shanmugasundram, A.; Börno, S.; Duvaux, L.; Lemaire, C.; Kuhl, H.; Klages, S.; Roberts, L. D.; Schade, S.; Gostner, J. M. et al.; Hildebrand, F.; Vowinckel, J.; Bichet, C.; Mülleder, M.; Calvani, E.; Zelezniak, A.; Griffin, J. L.; Bork, P.; Allaine, D.; Cohas, A.; Welch, J. J.; Timmermann, B.; Ralser, M.: Ice-age climate adaptations trap the Alpine marmot in a ,state of low genetic diversity. Current Biology 29 (10), pp. 1712 - 1720 (2019)

Charlton, J.; Downing, T. L.; Smith, Z. D.; Gu, H.; Clement, K.; Pop, R.; Akopian, V.; Klages, S.; Santos, D. P.; Tsankov, A. M. et al.; Timmermann, B.; Ziller, M. J.; Kiskinis, E.; Gnirke, A.; Meissner, A.: Global delay in nascent strand DNA methylation. Nature Structural and Molecular Biology 25 (4), pp. 327 - 332 (2018)

Charlton, J.; Downing, T. L.; Smith, Z. D.; Gu, H.; Clement, K.; Pop, R.; Akopian, V.; Klages, S.; Santos, D. P.; Tsankov, A. M. et al.; Timmermann, B.; Ziller, M. J.; Kiskinis, E.; Gnirke, A.; Meissner, A.: Author Correction: Global delay in nascent strand DNA methylation. Nature Structural and Molecular Biology 25 (4), p. 355 (2018)

Galonska, C.; Charlton, J.; Mattei, A. L.; Donaghey, J.; Clement, K.; Gu, H.; Mohammad, A. W.; Stamenova, E. K.; Cacchiarelli, D.; Klages, S. et al.; Timmermann, B.; Cantz, T.; Schöler, H. R.; Gnirke, A.; Ziller, M. J.; Meissner, A.: Genome-wide tracking of dCas9-methyltransferase footprints. Nature Communications 9, 597 (2018)

Satzger, I.; Marks, L.; Kerick, M.; Klages, S.; Berking, C.; Herbst, R.; Völker, B.; Schacht, V.; Timmermann, B.; Gutzmer, R.: Allele frequencies of BRAFV600 mutations in primary melanomas and matched metastases and their relevance for BRAF inhibitor therapy in metastatic melanoma. Oncotarget 2015, 5634 (2015)

Frankl-Vilches, C.; Kuhl, H.; Werber, M.; Klages, S.; Kerick, M.; Bakker, A.; de Oliveira, E. H. C.; Reusch, C.; Capuano, F.; Vowinckel, J. et al.; Leitner, S.; Ralser, M.; Timmermann, B.; Gahr, M.: Using the canary genome to decipher the evolution of hormone-sensitive gene regulation in seasonal singing birds. Genome Biology: Biology for the Post-Genomic Era 16 (1), 16:19 (2015)

Tine, M.; Kuhl, H.; Gagnaire, P.-A.; Louro, B.; Desmarais, E.; Martins, R. S. T.; Hecht, J.; Knaust, F.; Belkhir, K.; Klages, S. et al.; Dieterich, R.; Stueber, K.; Piferrer, F.; Guinand, B.; Bierne, N.; Volckaert, F. A. M.; Bargelloni, L.; Power, D. M.; Bonhomme, F.; Canario, A. V. M.; Reinhardt, R.: European sea bass genome and its variation provide insights into adaptation to euryhalinity and speciation. Nature Communications 5 (5), 5:5770 (2014)

Lee, Y. P.; Giorgi, F. M.; Lohse, M.; Kvederaviciute, K.; Klages, S.; Usadel, B.; Meskiene, I.; Reinhardt, R.; Hincha, D. K.: Transcriptome sequencing and microarray design for functional genomics in the extremophile Arabidopsis relative Thellungiella salsuginea (Eutrema salsugineum). BMC Genomics 14, 14:793 (2013)

Kube, M.; Chernikova, T. N.; Al-Ramahi, Y.; Beloqui, A.; Lopez-Cortez, N.; Guazzaroni, M.-E.; Heipieper, H. J.; Klages, S.; Kotsyurbenko, O. R.; Langer, I. et al.; Nechitaylo, T. Y.; Lünsdorf, H.; Fernández, M.; Juárez, S.; Ciordia, S.; Singer, A.; Kagan, O.; Egorova, O.; Alain Petit, P.; Stogios, P.; Kim, Y.; Tchigvintsev, A.; Flick, R.; Denaro, R.; Genovese, M.; Albar, J. P.; Reva, O. N.; Martínez-Gomariz, M.; Tran, H.; Ferrer, M.; Savchenko, A.; Yakunin, A. F.; Yakimov, M. M.; Golyshina, O. V.; Reinhardt, R.; Golyshin, P. N.: Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. Nature Communications 4, 4:2156 (2013)

Clark, M. S.; Denekamp, N. Y.; Thorne, M. A.; Reinhardt, R.; Drungowski, M.; Albrecht, M.; Klages, S.; Beck, A.; Kube, M.; Lubzens, E.: Long-term survival of hydrated resting eggs from Brachionus plicatilis. PLoS One 7 (1), p. e29365 - e29365 (2012)

Spanu, P. D.; Abbott, J. C.; Amselem, J.; Burgis, T. A.; Soanes, D. M.; Stüber, K.; Ver Loren van Themaat, E.; Brown, J. K. M.; Butcher, S. A.; Gurr, S. J. et al.; Lebrun, M.-H.; Ridout, C. J.; Schulze-Lefert, P.; Talbot, N. J.; Ahmadinejad, N.; Ametz, C.; Barton, G. R.; Benjdia, M.; Bidzinski, P.; Bindschedler, L. V.; Both, M.; Brewer, M. T.; Cadle-Davidson, L.; Cadle-Davidson, M. M.; Collemare, J.; Cramer, R.; Frenkel, O.; Godfrey, D.; Harriman, J.; Hoede, C.; King, B. C.; Klages, S.; Kleemann, J.; Knoll, D.; Koti, P. S.; Kreplak, J.; López-Ruiz, F. J.; Lu, X.; Maekawa, T.; Mahanil, S.; Micali, C.; Milgroom, M. G.; Montana, G.; Noir, S.; O’Connell, R. J.; Oberhaensli, S.; Parlange, F.; Pedersen, C.; Quesneville, H.; Reinhardt, R.; Rott, M.; Sacristán, S.; Schmidt, S. M.; Schön, M.; Skamnioti, P.; Sommer, H.; Stephens, A.; Takahara, H.; Thordal-Christensen, H.; Vigouroux, M.; Weßling, R.; Wicker, T.; Panstruga, R.: Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in extreme parasitism. Science 330 (6010), pp. 1543 - 1546 (2010)

Sadd, B. M.; Kube, M.; Klages, S.; Reinhardt, R.; Schmid-Hempel, P.: Analysis of a normalised expressed sequence tag (EST) library from a key pollinator, the bumblebee Bombus terrestris. BMC Genomics 11, p. 11:110 - 11:110 (2010)