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Zeitschriftenartikel (20)

1.
Zeitschriftenartikel
Verheijen, M.; Lienhard, M.; Schrooders, Y.; Clayton, O.; Nudischer, R.; Boerno, S. T.; Timmermann, B.; Selevsek, N.; Schlapbach, R.; Gmuender, H. et al.; Gotta, S.; Geraedts, J.; Herwig, R.; Kleinjans, J.; Caiment, F.: DMSO induces drastic changes in human cellular processes and epigenetic landscape in vitro. Scientific Reports 9 (9), 4641 (2019)
2.
Zeitschriftenartikel
Grimm, C.; Fischer, A.; Farrelly, A. M.; Kalachand, R.; Castiglione, R.; Wasserburger, E.; Hussong, M.; Schultheis, A. M.; Altmüller, J.; Thiele, H. et al.; Reinhardt, H. C.; Hauschulz, K.; Hennessy, B. T.; Herwig, R.; Lienhard, M.; Buettner, R.; Schweiger, M. R.: Combined Targeted Re-Sequencing of Cytosine DNA Methylation and Mutations of DNA Repair Genes with Potential Use for PARP1 Inhibitor Sensitivity Testing. The Journal of Molecular Diagnostics 21 (2), S. 198 - 213 (2019)
3.
Zeitschriftenartikel
Grimm, C.; Fischer, A.; Farrelly, A. M.; Kalachand, R.; Castiglione, R.; Wasserburger, E.; Hussong, M.; Schultheis, A. M.; Altmuller, J.; Thiele, H. et al.; Reinhardt, H. C.; Hauschulz, K.; Hennessy, B. T.; Herwig, R.; Lienhard, M.; Buettner, R.; Schweiger, M. R.: Combined Targeted Resequencing of Cytosine DNA Methylation and Mutations of DNA Repair Genes with Potential Use for Poly(ADP-Ribose) Polymerase 1 Inhibitor Sensitivity Testing. The Journal of Molecular Diagnostics 21 (2), S. 198 - 213 (2019)
4.
Zeitschriftenartikel
Verheijen, M. C. T.; Schrooders, Y.; Nudischer, R.; Börno, S. T.; Schlapbach, R.; Gotta, S.; Kleinjans, J. C. S.; Lienhard, M.; Clayton, O.; Timmermann, B. et al.; Selevsek, N.; Gmuender, H.; Herwig, R.; Caiment, F.: DMSO-induced drastic changes in cellular processes and epigenetic landscape in vitro. TOXICOLOGY LETTERS 2018, 295:S215 (2018)
5.
Zeitschriftenartikel
Grasse, S.; Lienhard, M.; Frese, S.; Kerick, M.; Steinbach, A.; Grimm, C.; Hussong, M.; Rolff, J.; Becker, M.; Dreher, F. et al.; Schirmer, U.; Boerno, S. T.; Ramisch, A.; Leschber, G.; Timmermann, B.; Grohé, C.; Lüders, H.; Vingron, M.; Fichtner, I.; Klein, S.; Odenthal, M.; Büttner, R.; Lehrach, H.; Sültmann, H.; Herwig, R.; Schweiger, R. M.: Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance. Genome Medicine 10 (1), 10:55 (2018)
6.
Zeitschriftenartikel
Herwig, R.; Hardt, C.; Lienhard, M.; Kamburov, A.: Analyzing and interpreting genome data at the network level with ConsensusPathDB. Nature Protocols 11 (10), S. 1889 - 1907 (2016)
7.
Zeitschriftenartikel
Poznik, G. D.; Xue, Y.; Mendez, F. L.; Willems, T. F.; Massaia, A.; Wilson Sayres, M. A.; The 1000 Genomes Projekt, C.; Lehrach, H.; Sudbrak, R.; Albrecht, M. W. et al.; Amstislavskiy, V.; Borodina, T. A.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M.-L.: Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences. Nature Genetics 48 (6), S. 593 - 599 (2016)
8.
Zeitschriftenartikel
The 1000 Genome Project Consortium; Lehrach, H.; Amstislavskiy, V.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M.-L.; Herwig, R.: A global reference for human genetic variation. Nature 526 (7571), S. 68 - 74 (2015)
9.
Zeitschriftenartikel
Kang, J.; Lienhard, M.; Pastor, W. A.; Chawla, A.; Novotny, M.; Tsagaratou, A.; Lasken, R. S.; Thompson, E. C.; Surani, M. A.; Koralov, S. B. et al.; Kalantry, S.; Chavez, L.; Rao, A.: Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis. Proceedings of the National Academy of Sciences of the United States of America 112 (31), S. E4236 - E4245 (2015)
10.
Zeitschriftenartikel
Etchegaray, J. P.; Chavez, L.; Huang, Y.; Ross, K. N.; Choi, J.; Martinez-Pastor, B.; Walsh, R. M.; Sommer, C. A.; Lienhard, M.; Gladden, A. et al.; Kugel, S.; Silberman, D. M.; Ramaswamy, S.; Mostoslavsky, G.; Hochedlinger, K.; Goren, A.; Rao, A.; Mostoslavsky, R.: The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine. Nature Cell Biology 17 (5), S. 545 - 557 (2015)
11.
Zeitschriftenartikel
Rasche, A.; Lienhard, M.; Yaspo, M.-L.; Lehrach, H.; Herwig, R.: ARH-seq: identification of differential splicing in RNA-seq data. Nucleic Acids Research (London) 42 (14), e110 (2014)
12.
Zeitschriftenartikel
Seumois, G.; Chavez, L.; Gerasimova, A.; Lienhard, M.; Omran, N.; Kalinke, L.; Vedanayagam, M.; Ganesan, A. P. V.; Chawla, A.; Djukanović, R. et al.; Ansel, K. M.; Peters, B.; Rao, A.; Vijayanand, P.: Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility. Nature Immunology 15 (8), S. 777 - 788 (2014)
13.
Zeitschriftenartikel
Delaneau, O.; Marchini, J.; 1000 Genomes Project, C.; Lehrach, H.; Sudbrak, R.; Amstislavskiy, V. S.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B. et al.; Yaspo, M. L.; Herwig, R.: Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel. Nature Communications 5, 5:3934 (2014)
14.
Zeitschriftenartikel
Lienhard, M.; Grimm, C.; Morkel, M.; Herwig, R.; Chavez, L.: MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments. Bioinformatics 30 (2), S. 284 - 286 (2014)
15.
Zeitschriftenartikel
Lienhard, M.; Grimm, C.; Morkel, M.; Herwig, R.; Chavez, L.: MEDIPS: genome wide differential coverage analysis of sequencing data derived from DNA enrichment experiments. Bioinformatics 30 (2), S. 284 - 286 (2014)
16.
Zeitschriftenartikel
Lienhard, M.; Grimm, C.; Morkel, M.; Herwig, R.; Chavez, L.: MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments. Bioinformatics 30 (2), S. 284 - 286 (2014)
17.
Zeitschriftenartikel
Khurana, E.; Fu, Y.; Colonna, V.; Mu, X. J.; Kang, H. M.; Lappalainen, T.; Sboner, A.; Lochovsky, L.; Chen, J.; Harmanci, A. et al.; Das, J.; Abyzov, A.; Balasubramanian, S.; Beal, K.; Chakravarty, D.; Challis, D.; Chen, Y.; Clarke, D.; Clarke, L.; Cunningham, F.; Evani, U. S.; Flicek, P.; Fragoza, R.; Garrison, E.; Gibbs, R.; Gumus, Z. H.; Herrero, J.; Kitabayashi, N.; Kong, Y.; Lage, K.; Liluashvili, V.; Lipkin, S. M.; MacArthur, D. G.; Marth, G.; Muzny, D.; Pers, T. H.; Ritchie, G. R.; Rosenfeld, J. A.; Sisu, C.; Wei, X.; Wilson, M.; Xue, Y.; Yu, F.; 1000 Genomes Project, C.; Lehrach, H.; Sudbrak, R.; Albrecht, M. W.; Amstislavskiy, V.; Borodina, T. A.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M. L.; Dermitzakis, E. T.; Yu, H.; Rubin, M. A.; Tyler-Smith, C.; Gerstein, M.: Integrative annotation of variants from 1092 humans: application to cancer genomics. Science 342 (6154), S. 1235587 - 1235587 (2013)
18.
Zeitschriftenartikel
Grimm, C.; Chavez, L.; Vilardell, M.; Farrall, A.; Tierling, S.; Böhm, J. W.; Grote, P.; Lienhard, M.; Dietrich, J.; Timmermann, B. et al.; Walter, J.; Schweiger, M. R.; Lehrach, H.; Herwig, R.; Herrmann, B. G.; Morkel, M.: DNA–Methylome Analysis of Mouse Intestinal Adenoma Identifies a Tumour-Specific Signature That Is Partly Conserved in Human Colon Cancer. PLoS Genetics 9 (2), S. e1003250 - e1003250 (2013)
19.
Zeitschriftenartikel
van Delft, J.; Gaj, S.; Lienhard, M.; Albrecht, M.; Kirpiy, A.; Brauers, K.; Claessen, S.; Lizarraga, D.; Lehrach, H.; Herwig, R. et al.; Kleinjans, J.: RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene. Toxicological Sciences 130 (2), S. 427 - 439 (2012)
20.
Zeitschriftenartikel
Abecasis, G. R.; Auton, A.; Brooks, L. D.; DePristo, M. A.; Durbin, R. M.; Handsaker, R. E.; Kang, H. M.; Marth, G. T.; McVean, G. A.; The 1000 Genomes Project Consortium et al.; Sudbrak, R.; Albrecht, M.; Amstislavskiy, V.; Borodina, T. A.; Davydov, A.; Herwig, R.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M. L.; Lehrach, H.: An integrated map of genetic variation from 1,092 human genomes. Nature 491 (7422), S. 56 - 65 (2012)
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