Publikationen von Alexander Meissner

Veenvliet, J. V.; Bolondi, A.; Kretzmer, H.; Haut, L.; Scholze-Wittler, M.; Schifferl, D.; Koch, F.; Guignard, L.; Sampath Kumar, A.; Pustet, M. et al.; Heimann, S.; Buschow, R.; Wittler, L.; Timmermann, B.; Meissner, A.; Herrmann, B. G.: Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites. Science 370 (6522), eaba4937 (2020)

Kretzmer, H.; Biran, A.; Purroy, N.; Lemvigh, C. K.; Clement, K.; Gruber, M.; Gu, H.; Rassenti, L.; Mohammad, A. W.; Lesnick, C. et al.; Slager, S. L.; Braggio, E.; Shanafelt, T. D.; Kay, N. E.; Fernandes, S. M.; Brown, J. R.; Wang, L.; Li, S.; Livak, K. J.; Neuberg, D. S.; Klages, S.; Timmermann, B.; Kipps, T. J.; Campo, E.; Gnirke, A.; Wu, C. J.; Meissner, A.: Pre-neoplastic alterations define CLL DNA methylome and persist through disease progression and therapy. Blood Cancer Discovery 2 (1), 2:1–16 (2020)

Grosswendt, S.; Kretzmer, H.; Smith, Z. D.; Sampath Kumar, A.; Hetzel, S.; Wittler, L.; Klages, S.; Timmermann, B.; Mukherji, S.; Meissner, A.: Epigenetic regulator function through mouse gastrulation. Nature 584, S. 102 - 108 (2020)

Charlton, J.; Jung, E. J.; Mattei, A. L.; Bailly, N.; Liao, J.; Martin, E. J.; Gießelmann, P.; Brändl, B.; Stamenova, E. K.; Müller, F.-J. et al.; Kiskinis, E.; Gnirke, A.; Smith, Z. D.; Meissner, A.: TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers. Nature Genetics 52 (8), S. 819 - 827 (2020)

The ENCODE Project Consortium; Snyder, M. P.; Gingeras, T. R.; Moore, J. E.; Weng, Z.; Gerstein, M. B.; Ren, B.; Hardison, R. C.; Stamatoyannopoulos, J. A.; Graveley, B. R. et al.; Feingold, E. A.; Pazin, M. J.; Pagan, M.; Gilchrist, D. A.; Hitz, B. C.; Cherry, J. M.; Bernstein, B. E.; Mendenhall, E. M.; Zerbino, D. R.; Frankish, A.; Flicek, P.; Myers , R. M.; Meissner, A.: Perspectives on ENCODE. Nature 583, S. 693 - 698 (2020)

Yagi, M.; Kabata, M.; Tanaka, A.; Ukai, T.; Ohta, S.; Nakabayashi, K.; Shimizu, M.; Hata, K.; Meissner, A.; Yamamoto, T. et al.; Yamada, Y.: Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development. Nature Communications 11, 3199 (2020)

Basu, S.; Mackowiak, S.; Niskanen, H.; Knezevic, D.; Asimi, V.; Grosswendt, S.; Geertsema, H.; Ali, S.; Jerković, I.; Ewers, H. et al.; Mundlos, S.; Meissner, A.; Ibrahim, D. M.; Hnisz, D.: Unblending of Transcriptional Condensates in Human Repeat Expansion Disease. Cell 181 (5), e30, S. 1062 - 1079 (2020)

Huyghe, A.; Furlan, G.; Ozmadenci, D.; Galonska, C.; Charlton, J.; Gaume, X.; Combémorel, N.; Riemenschneider, C.; Allègre, N.; Zhang, J. et al.; Wajda, P.; Rama, N.; Vieugué, P.; Durand, I.; Brevet , M.; Gadot, N.; Imhof, T.; Merrill , B. J.; Koch, M.; Mehlen, P.; Chazaud, C.; Meissner, A.; Lavial , F.: Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling. Nature Cell Biology 22 (4), S. 389 - 400 (2020)

Gokhman, D.; Nissim-Rafinia, M.; Agranat-Tamir, L.; Housman, G.; García-Pérez, R.; Lizano, E.; Cheronet, O.; Mallick, S.; Nieves-Colón, M. A.; Li, H. et al.; Alpaslan-Roodenberg, S.; Novak, M.; Gu, H.; Osinski, J. M.; Ferrando-Bernal, M.; Gelabert, P.; Lipende, I.; Mjungu, D.; Kondova, I.; Bontrop, R.; Kullmer, O.; Weber, G.; Shahar, T.; Dvir-Ginzberg, M.; Faerman, M.; Quillen, E. E.; Meissner, A.; Lahav, Y.; Kandel, L.; Liebergall, M.; Prada, M. E.; Vidal, J. M.; Gronostajski, R. M.; Stone, A. C.; Yakir, B.; Lalueza-Fox, C.; Pinhasi, R.; Reich, D.; Marques-Bonet, T.; Meshorer, E.; Carmel, L.: Differential DNA methylation of vocal and facial anatomy genes in modern humans. Nature Communications 11, 1189 (2020)

Alvarez-Dominguez, J. R.; Donaghey, J.; Rasouli, N.; Kenty, J. H. R.; Helman, A.; Charlton, J.; Straubhaar, J. R.; Meissner, A.; Melton, D. A.: Circadian Entrainment Triggers Maturation of Human In Vitro Islets. Cell Stem Cell 26 (1), e10, S. 108 - 122 (2020)

Gießelmann, P.; Brändl, B.; Raimondeau, E.; Bowen, R.; Rohrandt, C.; Tandon, R.; Kretzmer, H.; Assum, G.; Galonska, C.; Siebert, R. et al.; Ammerpohl, O.; Heron, A.; Schneider, S. A.; Ladewig, J.; Koch, P.; Schuldt, B. M.; Graham, J. E.; Meissner, A.; Müller, F.-J.: Analysis of short tandem repeat expansions and their methylation state with nanopore sequencing. bioRxiv (Preprint Server), 480285 (2019)

Kottakis, F.; Nicolay, B. N.; Roumane, A.; Karnik, R.; Gu, H.; Nagle, J. M.; Boukhali, M.; Hayward, M. C.; Li, Y. Y.; Chen, T. et al.; Liesa, M.; Hammerman, P. S.; Wong, K. K.; Hayes, D. N.; Shirihai, O. S.; Dyson, N. J.; Haas, W.; Meissner, A.; Bardeesy, N.: Author Correction: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature 575 (7783), E5 (2019)

Andergassen, D.; Smith, Z. D.; Lewandowski, J. P.; Gerhardinger, C.; Meissner, A.; Rinn, J. L.: In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation. eLife 8, e47214 (2019)

Di Stefano, B.; Luo, E.-C.; Haggerty, C.; Aigner, S.; Charlton, J.; Brumbaugh, J.; Ji, F.; Rabano Jiménez, I.; Clowers, K. J.; Huebner, A. J. et al.; Clement, K.; Lipchina, I.; de Kort, M. A. C.; Anselmo, A.; Pulice, J.; Gerli, M. F. M.; Gu, H.; Gygi, S. P.; Sadreyev, R. I.; Meissner, A.; Yeo, G. W.; Hochedlinger, K.: The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis. Cell Stem Cell 25 (5), e13, S. 622 - 638 (2019)

Brumbaugh , J.; Kim, I. S.; Ji, F.; Huebner, A. J.; Di Stefano , B.; Schwarz, B. A.; Charlton, J.; Coffey, A.; Choi, J.; Walsh, R. M. et al.; Schindler, J. W.; Anselmo, A.; Meissner, A.; Sadreyev, R. I.; Bernstein, B. E.; Hock, H.; Hochedlinger , K.: Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo. Nature Cell Biology 21 (11), S. 1449 - 1461 (2019)

Tsankov, A. M.; Wadsworth, M. H.; Akopian, V.; Charlton, J.; Allon, S. J.; Arczewska, A. A.; Mead, B. E.; Drake, R. S.; Smith, Z. D.; Mikkelsen, T. S. et al.; Shalek, A. K.; Meissner, A.: Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression. Development 2019, 146 (2019)

Giesselmann, P.; Hetzel, S.; Müller, F.-J.; Meissner, A.; Kretzmer, H.: Nanopype: A modular and scalable nanopore data processing pipeline. Bioinformatics 2019, btz461 (2019)

Modic, M.; Grosch, M.; Rot, G.; Schirge, S.; Lepko, T.; Yamazaki, T.; Lee, F. C. Y.; Rusha, E.; Shaposhnikov, D.; Palo, M. et al.; Merl-Pham, J.; Cacchiarelli, D.; Rogelj, B.; Hauck, S. M.; von Mering, C.; Meissner, A.; Lickert, H.; Hirose, T.; Drukker, M.: Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Molecular Cell 74 (5), e13, S. 951 - 965 (2019)

Chan, M. M.; Smith, Z. D.; Grosswendt, S.; Kretzmer, H.; Norman, T. M.; Adamson, B.; Jost, M.; Quinn, J. J.; Yang, D.; Jones, M. G. et al.; Khodaverdian, A.; Nir, Y.; Meissner, A.; Weissman, J. S.: Molecular recording of mammalian Embryogenesis. Nature 570 (7759), S. 77 - 82 (2019)

Gaiti, F.; Chaligne, R.; Gu, H.; Brand, R. M.; Kothen-Hill, S.; Schulman, R. C.; Grigorev, K.; Risso, D.; Kim, K.-T.; Pastore, A. et al.; Huang, K. Y.; Alonso, A.; Sheridan, C.; Omans, N. D.; Biederstedt, E.; Clement, K.; Wang, L.; Felsenfeld, J. A.; Bhavsar, E. B.; Aryee, M. J.; Allan, J. N.; Furman, R.; Gnirke, A.; Wu, C. J.; Meissner, A.; Landau, D. A.: Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia. Nature 569 (7757), S. 576 - 580 (2019)