Max Planck Institute for Molecular Genetics

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Prof. Dr. Alexander Meissner

Research Group Leader, Scientific member, director (030) 8413 1880 meissner@... office-meissner@...

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Cordula Mancini

Secretary (030) 8413 1881 (030) 8413 1961 office-meissner@...

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ERC Advanced Grant for Alex Meissner

Honorary Professorship of Freie Universität Berlin for Alexander Meissner

Latest Publications

Abhishek Sampath Kumar, Luyi Tian, Adriano Bolondi, Amèlia Aragonés Hernández, Robert Stickels, Helene Kretzmer, Evan Murray, Lars Wittler, Maria Walther, Gabriel Barakat, Leah Haut, Yechiel Elkabetz, Evan Z. Macosko, Léo Guignard, Fei Chen & Alexander Meissner

Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis

Nature Genetics

Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis

Weigert R, Hetzel S, Bailly N, Haggerty C, Ilik IA, …, Bolondi A, Kumar AS, …, Brändl B, Meierhofer D, Lupiáñez DG, Müller FJ, Aktas T, …, Kretzmer H, Smith ZD, Meissner A.

Dynamic antagonism between key repressive pathways maintains the placental epigenome

Nat Cell Biol.

Dynamic antagonism between key repressive pathways maintains the placental epigenome

Landshammer A, Bolondi A, Kretzmer H, …, Buschow R, …, Mackowiak SD, Braendl B, Giesselmann P, Tornisiello R, …, Mielke T, Meierhofer D, … Hnisz D, …, Meissner A.

T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation.

Elife.

T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation.

Asimi V, Sampath Kumar A, Niskanen H, Riemenschneider C, Hetzel S, Naderi J, …, Kretzmer H, Smith ZD, Weigert R, Walther M, Mamde S, Meierhofer D, Wittler L, Buschow R, Timmermann B, …, Meissner A, Hnisz D.

Hijacking of transcriptional condensates by endogenous retroviruses.

Nature Genetics

Hijacking of transcriptional condensates by endogenous retroviruses

Hetzel S, Mattei AL, Kretzmer H, …, Mullighan CG, Meissner A.

Acute lymphoblastic leukemia displays a distinct highly methylated genome.

Nature Cancer

Acute lymphoblastic leukemia displays a distinct highly methylated genome.

Mattei AL, Bailly N, Meissner A.

DNA methylation: a historical perspective.

Trends Genet.

DNA methylation: a historical perspective

Andergassen D, Smith ZD, Kretzmer H, Rinn JL, Meissner A.

Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages.

https://www.sciencedirect.com/science/article/pii/S153458072100811X?via%3Dihub

Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages

Hetzel S, Giesselmann P, Reinert K, Meissner A, Kretzmer H.

RLM: Fast and simplified extraction of Read-Level Methylation metrics from bisulfite sequencing data.

https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btab663/6380544

RLM: Fast and simplified extraction of Read-Level Methylation metrics from bisulfite sequencing data.

Wu HJ, Landshammer A, Stamenova EK, Bolondi A, Kretzmer H, Meissner A, Michor F.

Topological isolation of developmental regulators in mammalian genomes.

Nat Commun 12, 4897 (2021). https://doi.org/10.1038/s41467-021-24951-7

Topological isolation of developmental regulators in mammalian genomes.

Chuck Haggerty, Helene Kretzmer, Christina Riemenschneider, Abhishek Sampath Kumar, Alexandra L. Mattei, Nina Bailly, Judith Gottfreund, Pay Giesselmann, Raha Weigert, Björn Brändl, Pascal Giehr, René Buschow, Christina Galonska, Ferdinand von Meyenn, Melissa B. Pappalardi, Michael T. McCabe, Lars Wittler, Claudia Giesecke-Thiel, Thorsten Mielke, David Meierhofer, Bernd Timmermann, Franz-Josef Müller, Jörn Walter & Alexander Meissner

Dnmt1 has de novo activity targeted to transposable elements

Nature Structural & Molecular Biology, 17June2021

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