Publikationen von Alexander Meissner

Galonska, C.; Charlton, J.; Mattei, A. L.; Donaghey, J.; Clement, K.; Gu, H.; Mohammad, A. W.; Stamenova, E. K.; Cacchiarelli, D.; Klages, S. et al.; Timmermann, B.; Cantz, T.; Schöler, H. R.; Gnirke, A.; Ziller, M. J.; Meissner, A.: Genome-wide tracking of dCas9-methyltransferase footprints. Nature Communications 9, 9:597 (2018)

Janssens, S.; Schotsaert, M.; Karnik, R.; Balasubramaniam, V.; Dejosez, M.; Meissner, A.; García-Sastre, A.; Zwaka, T. P.: Zika Virus Alters DNA Methylation of Neural Genes in an Organoid Model of the Developing Human Brain. mSystems 3 (1), e00219-17 (2018)

Donaghey, J.; Thakurela, S.; Charlton, J.; Chen, J. S.; Smith, Z. D.; Gu, H.; Pop, R.; Clement, K.; Stamenova, E. K.; Karnik, R. et al.; Kelley, D. R.; Gifford, C. A.; Cacchiarelli, D.; Rinn, J. L.; Gnirke, A.; Ziller, M. J.; Meissner, A.: Genetic determinants and epigenetic effects of pioneer-factor occupancy. Nature Genetics 50 (2), S. 250 - 258 (2018)

Du, P.; Pirouz, M.; Choi, J.; Huebner, A. J.; Clement, K.; Meissner, A.; Hochedlinger, K.; Gregory, R. I.: An Intermediate Pluripotent State Controlled by MicroRNAs Is Required for the Naive-to-Primed Stem Cell Transition. Cell Stem Cell 22 (6), e5, S. 851 - 864 (2018)

Smith, Z. D.; Shi, J.; Gu, H.; Donaghey, J.; Clement, K.; Cacchiarelli, D.; Gnirke, A.; Michor, F.; Meissner, A.: Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer. Nature 549 (7673), S. 543 - 547 (2017)

Choi, J.; Huebner, A. J.; Clement, K.; Walsh, R. M.; Savol, A.; Lin, K.; Gu, H.; Di Stefano, B.; Brumbaugh, J.; Kim, S.-Y. et al.; Sharif, J.; Rose, C. M.; Mohammad, A.; Odajima, J.; Charron, J.; Shioda, T.; Gnirke, A.; Gygi, S.; Koseki, H.; Sadreyev, R. I.; Xiao, A.; Meissner, A.; Hochedlinger, K.: Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells. Nature 548 (7666), S. 219 - 223 (2017)

Choi, J.; Clement, K.; Huebner, A. J.; Webster, J.; Etchegaray, J.-P.; Gu, H.; Boyle, P.; Elling, U.; Mostoslavsky, R.; Sadreyev, R. et al.; Park, P. J.; Gygi, S. P.; Meissner, A.; Hochedlinger, K.: DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells. Cell Stem Cell 20 (5), S. 706 - 719 (2017)

Warren, C. R.; O’Sullivan, J. F.; Friesen, M.; Becker, C. E.; Zhang, X.; Liu, P.; Wakabayashi, Y.; Morningstar, J. E.; Shi, X.; Choi, J. et al.; Xia, F.; Peters, D. T.; Florido, M. H. C.; Tsankov, A. M.; Duberow, E.; Comisar, L.; Shay, J.; Jiang, X.; Meissner, A.; Musunuro, K.; Kathiresan, S.; Daheron, L.; Zhu, J.; Gerszten, R. E.; Deo, R. C.; Vasan, R. S.; O’Donnell, C. J.; Cowan, C. A.: Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. Cell Stem Cell 20 (4), S. 547 - 557 (2017)

Yu , V. W. C.; Yusuf , R. Z.; Oki , T.; Wu, J.; Saez, B.; Wang, X.; Cook , C.; Baryawno , N.; Ziller , M. J.; Lee , E. et al.; Gu, H.; Meissner, A.; Lin, C. P.; Kharchenko, P. V.; Scadden , D. T.: Correction: Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells. Cell 168 (5), S. 944 - 945 (2017)

Liu , L. L.; Brumbaugh , J.; Bar-Nur , O.; Smith , Z.; Stadtfeld , M.; Meissner, A.; Hochedlinger, K.; Michor, F.: Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells. Cell Reports 17 (12), S. 3395 - 3406 (2016)

Ziller, M. J.; Stamenova, E. K.; Gu, H.; Gnirke, A.; Meissner, A.: Targeted bisulfite sequencing of the dynamic DNA methylome. Epigenetics & Chromatin 9, 9:55 (2016)

Kottakis, F.; Nicolay, B. N.; Roumane, A.; Karnik, R.; Gu, H.; Nagle, J. M.; Boukhali, M.; Hayward, M. C.; Li, Y. Y.; Chen, T. et al.; Liesa, M.; Hammerman, P. S.; Wong, K. K.; Hayes, D. N.; Shirihai, O. S.; Dyson, N. J.; Haas, W.; Meissner, A.; Bardeesy, N.: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature 539 (7629), S. 390 - 395 (2016)

Yu , V. W. C.; Yusuf , R. Z.; Oki , T.; Wu, J.; Saez, B.; Wang, X.; Cook , C.; Baryawno , N.; Ziller , M. J.; Lee , E. et al.; Gu, H.; Meissner, A.; Lin, C. P.; Kharchenko, P. V.; Scadden , D. T.: Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells. Cell 167 (5), e17, S. 1310 - 1322 (2016)

Aguilar, C. A.; Pop, R.; Shcherbina, A.; Watts, A.; Matheny Jr., R. W.; Cacchiarelli, D.; Han, W. M.; Shin, E.; Nakhai, S. A.; Jang, Y. C. et al.; Carrigan, C. T.; Gifford, C. A.; Kottke, M. A.; Cesana, M.; Lee, J.; Urso, M. L.; Meissner, A.: Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma. Stem Cell Reports 7 (5), S. 983 - 997 (2016)

Libertini, E.; Heath, S. C.; Hamoudi, R. A.; Gut, M.; Ziller, M. J.; Herrero, J.; Czyz, A.; Ruotti, V.; Stunnenberg, H. G.; Frontini, M. et al.; Ouwehand, W. H.; Meissner, A.: Saturation analysis for whole-genome bisulfite sequencing data. Nature Biotechnology 34 (7), S. 691 - 693 (2016)

Libertini, E.; Heath, S. C.; Hamoudi, R. A.; Gut, M.; Ziller, M. J.; Czyz, A.; Ruotti, V.; Stunnenberg, H. G.; Frontini, M.; Ouwehand, W. H. et al.; Meissner, A.: Information recovery from low coverage whole-genome bisulfite sequencing. Nature Communications 2016, 7:11306 (2016)

Smith, Z. D.; Sindhu, C.; Meissner, A.: Molecular features of cellular reprogramming and development. Nature Reviews Molecular Cell Biology 17 (3), S. 139 - 154 (2016)

Bolondi, A.; Kretzmer, H.; Meissner, A.: Single-cell technologies: a new lens into epigenetic regulation in development. (2022)

McGuire, A. L.; Gabriel, S.; Tishkoff, S. A.; Wonkam, A.; Chakravarti, A.; Furlong, E. E. M.; Treutlein, B.; Meissner, A.; Chang, H. Y.; López-Bigas, N. et al.; Segal, E.; Kim, J.-S.: The road ahead in genetics and genomics. (2020)

Ravid-Lustig, L.; Sampath Kumar, A.; Schwämmle, T.; Dunkel, I.; Noviello, G.; Weigert, R.; Pacini, G.; Buschow, R.; Ghauri, A.; Stötzel, M. et al.; Wittler, L.; Meissner, A.; Schulz, E. G.: GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of a distal enhancer element. (2022)