Publications of B. Timmermann

Röhr, C.; Kerick, M.; Fischer, A.; Kuehn, A.; Kashofer, K.; Timmermann, B.; Daskalaki, A.; Meinel, T.; Drichel, D.; Börno, S. et al.; Nowka, A.; Krobitsch, S.; McHardy, A. C.; Kratsch, C.; Becker, T.; Wunderlich, A.; Barmeyer, C.; Viertler, C.; Zatloukal, K.; Wierling, C.; Lehrach, H.; Schweiger, M.-R.: High-Throughput miRNA and mRNA Sequencing of Paired Colorectal Normal, Tumor and Metastasis Tissues and Bioinformatic Modeling of miRNA-1 Therapeutic Applications. PLoS One 8 (7), p. e67461 - e67461 (2013)

Montgomery, S. B.; Goode, D. L.; Kvikstad, E.; Albers, C. H.; Zhang, Z. D.; Mu, X. J.; Ananda, G.; Howie, B.; Karczewski, K. J.; Smith, K. S. et al.; Anaya, V.; Richardson, R.; Davis, J.; 1000 Genome Project, C.; Timmermann, B.; MacArthur, D. G.; Sidow, A.; Duret, L.; Gerstein, M.; Makova, K. D.; Marchini, J.; McVean, G.; Lunter, G.: The origin, evolution, and functional impact of short insertion-deletion variants identified in 179 human genomes. Genome Research 23 (5), pp. 749 - 761 (2013)

Feldmann, R.; Fischer, C.; Kodelja, V.; Behrens, S.; Haas, S.; Vingron, M.; Timmermann, B.; Geikowski, A.; Sauer, S.: Genome-wide analysis of LXRalpha activation reveals new transcriptional networks in human atherosclerotic foam cells. Nucleic Acids Research (London) 41 (6), pp. 3518 - 3531 (2013)

Feldmann, R.; Fischer, C.; Kodelja, V.; Behrens, S.; Haas, S.; Vingron, M.; Timmermann, B.; Geikowski, A.; Sauer, S.: Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells. Nucleic Acids Research (London) 41 (6), pp. 3518 - 3531 (2013)

Weimann, M.; Grossmann, A.; Woodsmith, J.; Özkan, Z.; Birth, P.; Meierhofer, D.; Benlasfer, N.; Valovka, T.; Timmermann, B.; Wanker, E. E. et al.; Sauer, S.; Stelzl, U.: A Y2H-seq approach defines the human protein methyltransferase interactome. Nature methods 10 (4), pp. 339 - 342 (2013)

Bu, H.; Schweiger, M. R.; Manke, T.; Wunderlich, A.; Timmermann, B.; Kerick, M.; Pasqualini, L.; Shehu, E.; Fuchsberger, C.; Cato, A. C. et al.; Klocker, H.: Anterior gradient 2 and 3--two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells. FEBS Journal 280 (5), pp. 1249 - 66 (2013)

Grimm, C.; Chavez, L.; Vilardell, M.; Farrall, A.; Tierling, S.; Böhm, J. W.; Grote, P.; Lienhard, M.; Dietrich, J.; Timmermann, B. et al.; Walter, J.; Schweiger, M. R.; Lehrach, H.; Herwig, R.; Herrmann, B. G.; Morkel, M.: DNA–Methylome Analysis of Mouse Intestinal Adenoma Identifies a Tumour-Specific Signature That Is Partly Conserved in Human Colon Cancer. PLoS Genetics 9 (2), p. e1003250 - e1003250 (2013)

Schweiger, M. R.; Barmeyer, C.; Timmermann, B.: Genomics and epigenomics: new promises of personalized medicine for cancer patients. Briefings in Functional Genomics 12 (5), pp. 411 - 21 (2013)

Xue, Y.; Chen, Y.; Ayub, Q.; Huang, N.; Ball, E. V.; Mort, M.; Phillips, A. D.; Shaw, K.; Stenson, P. D.; Cooper, D. N. et al.; Tyler-Smith, C.; The 1000 Genomes Project Consortium; Timmermann, B.; Lehrach, H.; Herwig, R.: Deleterious- and Disease-Allele Prevalence in Healthy Individuals: Insights from Current Predictions, Mutation Databases, and Population-Scale Resequencing. The American Journal of Human Genetics 91 (6), pp. 1022 - 1031 (2012)

Bulk, E.; Yu, J.; Hascher, A.; Koschmieder, S.; Wiewrodt, R.; Krug, U.; Timmermann, B.; Marra, A.; Hillejan, L.; Wiebe, K. et al.; Berdel, W. E.; Schwab, A.; Müller-Tidow, C.: Mutations of the EPHB6 receptor tyrosine kinase induce a pro-metastatic phenotype in non-small cell lung cancer. PLoS One 7 (12), e44591 (2012)

Türkmen, S.; Timmermann, B.; Bartels, G.; Gröger, D.; Meyer, C.; Schwartz, S.; Haferlach, C.; Rieder, H.; Gökbuget, N.; Hoelzer, D. et al.; Marschalek, R.; Burmeister, T.: Involvement of the MLL gene in adult T-lymphoblastic leukemia. Genes, Chromosomes and Cancer 51 (12), pp. 1114 - 1124 (2012)

Abecasis, G. R.; Auton, A.; Brooks, L. D.; DePristo, M. A.; Durbin, R. M.; Handsaker, R. E.; Kang, H. M.; Marth, G. T.; McVean, G. A.; The 1000 Genomes Project Consortium et al.; Sudbrak, R.; Albrecht, M.; Amstislavskiy, V.; Borodina, T. A.; Davydov, A.; Herwig, R.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M. L.; Lehrach, H.: An integrated map of genetic variation from 1,092 human genomes. Nature 491 (7422), pp. 56 - 65 (2012)

Börno, S.; Fischer, A.; Kerick, M.; Falth, M.; Laible, M.; Brase, J. C.; Kuner, R.; Dahl, A.; Grimm, C.; Sayanjali, B. et al.; Isau, M.; Röhr, C.; Wunderlich, A.; Timmermann, B.; Claus, R.; Plass, C.; Graefen, M.; Simon, R.; Demichelis, F.; Rubin, M. A.; Sauter, G.; Schlomm, T.; Sültmann, H.; Lehrach, H.; Schweiger, M. R.: Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation. Cancer Discovery 2 (11), pp. 1024 - 1035 (2012)

Spielmann, M.; Brancati, F.; Krawitz, P. M.; Robinson, P. N.; Ibrahim, D. M.; Franke, M.; Hecht, J.; Lohan, S.; Dathe, K.; Nardone, A. M. et al.; Ferrari, P.; Landi, A.; Wittler, L.; Timmermann, B.; Chan, D.; Mennen, U.; Klopocki, E.; Mundlos, S.: Homeotic arm-to-leg transformation associated with genomic rearrangements at the PITX1 locus. American Journal of Human Genetics 91 (4), pp. 629 - 635 (2012)

Ralser, M.; Timmermann, B.: Genomanalyse von Modellorganismen: Saccharomyces cerevisiae. Biospektrum 18 (5), pp. 504 - 507 (2012)

Ralser, M.; Kuhl, H.; Ralser, M.; Werber, M.; Lehrach, H.; Breitenbach, M.; Timmermann, B.: The Saccharomyces cerevisiae W303-K6001 cross-platform genome sequence: insights into ancestry and physiology of a laboratory mutt. Open Biology 2 (8), 120093 (2012)

The 1000 Genomes Project Consortium; Sudbrak, R.; Albrecht, M.; Amstislavskiy, V.; Borodina, T. A.; Dahl, A.; Davydov, A.; Herwig, R.; Marquardt, P.; Mertes, F. et al.; Nietfeld, W.; Parkhomchuk, D.; Soldatov, A.; Timmermann, B.; Tolzmann, M.; Lehrach, H.: The 1000 Genomes Project: data management and community access. Nature methods 9 (5), pp. 459 - 462 (2012)

MacArthur, D. G.; Balasubramanian, S.; Frankish, A.; 1000 Genomes Project, C.; Sudbrak, R.; Albrecht , M. W.; Amstislavskiy, V.; Borodina, T. A.; Dahl, A.; Davydov, A. et al.; Herwig, R.; Marquardt, P.; Mertes, F.; Nietfeld, W.; Parkhomchuk, D.; Soldatov, A.; Timmermann, B.; Tolzmann, M.; Lehrach, H.: A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes. Science 335 (6070), pp. 823 - 828 (2012)

Goke, J.; Jung, M.; Behrens, S.; Chavez, L.; O'Keeffe, S.; Timmermann, B.; Lehrach, H.; Adjaye, J.; Vingron, M.: Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development. PLoS Comput Biol 7 (12), e1002304 (2011)

Kerick, M.; Isau, M.; Timmermann, B.; Sultmann, H.; Herwig, R.; Krobitsch, S.; Schaefer, G.; Verdorfer, I.; Bartsch, G.; Klocker, H. et al.; Lehrach, H.; Schweiger, M. R.: Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity. BMC Med Genomics 4, p. 68 (2011)