Wei Xie: Decoding the transcription circuitry when the life begins

Dr. Wei Xie is a Professor and Vice Dean of School of Life Sciences, Tsinghua University, and also an HHMI International Research Scholar. His lab is interested in understanding epigenetic regulation of transcription in the mammalian genome that governs development and related human diseases. For this purpose they use a variety of methods in molecular biology, developmental biology, genomics and bioinformatics. His group established a series of ultra-sensitive technologies to analyze chromatin dynamics using hundreds of cells or fewer. By doing so, his team revealed how chromatin accessibility, histone modifications, and 3D chromatin architecture are reprogrammed during early mammalian development. His work also demonstrated how the embryonic program is activated during zygotic genome activation.

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This is an in-person event.