Protein networks: How protein interactions define shape and function of cells

Research report (imported) 2010 - Max Planck Institute for Molecular Genetics

Authors
Stelzl, Ulrich
Departments
Otto-Warburg-Laboratorium - Molekulare Interaktions-Netzwerke (Dr. Ulrich Stelzl)
MPI für molekulare Genetik, Berlin
Summary
Systematic protein interaction studies are an important part of functional genomics research. A powerful method to decipher protein-protein interaction networks is the yeast two-hybrid system that allows studying the possible interaction of billions of protein pairs. Resulting interactions are represented in protein networks which provide a framework for a systems understanding of the molecular biology of the cell and contribute to medical practice, facilitating identification of human disease genes and an improved interpretation of patient samples and records.

For the full text, see the German version.

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