Publications
The following publications were published exclusively under the affiliation of the Max Planck Society. For publications by the principal investigator outside of the Max Planck Society, see the links on the lower left.
Publications by the Smith Lab
Preprints
If preprints are available, they will be listed here.
No matching publications found.
Published
2025
Hetzel, S.; Hodis , E.; Torlai Triglia, E.; Kovacsovics, A.; Steinmann , K.; Gnirke, A.; Cui, M.; McQuaid, D.; Weigert, R.; Pohl, G. et al.; Muzumdar, M. D.; Leyvraz, S.; Keilholz, U.; Yaspo, M.-L.; Regev, A.; Kretzmer, H.; Smith, Z.; Meissner, A.: Direct genetic transformation bypasses tumor-associated DNA methylation alterations. Genome Biology (26) (2025)
2024
Hasenbein, T. P.; Hoelzl, S.; Smith, Z. D.; Gerhardinger, C.; Gonner, M. O. C.; Aguilar-Pimentel, A.; Amarie, O. V.; Becker, L.; Calzada-Wack, J.; Dragano, N. R. V. et al.; da Silva-Buttkus, P.; Garrett, L.; Hölter, S. M.; Kraiger, M.; Östereicher, M. A.; Rathkolb, B.; Sanz-Moreno, A.; Spielmann, N.; Wurst, W.; Gailus-Durner, V.; Fuchs, H.; Hrabě de Angelis, M.; Meissner, A.; Engelhardt, S.; Rinn, J. L.; Andergassen, D.: X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes. Nature Communications
15 (1), Article 10631 (2024)
Zagoren, E.; Dias, N.; Smith, Z. D.: A second wave of Notch signaling diversifies the intestinal secretory lineage. bioRxiv (2024)
Bolondi, A.; Law, B. K.; Kretzmer, H.; Gassaloglu, S. I.; Buschow, R.; Riemenschneider, C.; Yang, D.; Walther, M.; Veenvliet, J. V.; Meissner, A. et al.; Smith, Z. D.; Chan, M. M.: Reconstructing axial progenitor field dynamics in mouse stem cell-derived embryoids. Developmental Cell
59 (12), pp. 1489 - 1505 (2024)
2023
Weigert, R.; Hetzel, S.; Bailly, N.; Haggerty, C.; Ilik, I. A.; Kwong Yung, P. Y.; Navarro, C.; Bolondi, A.; Sampath Kumar, A.; Anania, C. et al.; Brändl, B.; Meierhofer, D.; Lupiáñez, D. G.; Müller, F.-J.; Aktas, T.; Elsässer, S. J.; Kretzmer, H.; Smith, Z. D.; Meissner, A.: Dynamic antagonism between key repressive pathways maintains the placental epigenome. Nature Cell Biology
25 (4), pp. 579 - 591 (2023)
Publications by Dr. Zachary Smith before 2023
1.
Monique Pedroza, Seher Ipek Gassaloglu, Nicolas Dias, Liangwen Zhong, Tien-Chi Jason Hou, Helene Kretzmer, Zachary D. Smith, Berna Sozen
Self-patterning of human stem cells into post-implantation lineages
Nature volume 622, pages 574–583 (2023)
2.
Aushaq B Mall , Haoming Yu, Delaney Farris, Srilekha Kadimi, TuKiet T Lam, Andy L Cox, Zachary D Smith, Bluma J Lesch
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
EMBO Rep. 2023 Aug
3.
Aushaq B Malla, Shannon R Rainsford, Zachary D Smith, Bluma J Lesch
DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-protamine replacement
Development. 2023
4.
Raha Weigert, Sara Hetzel, Nina Bailly, Chuck Haggerty, Ibrahim A. Ilik, Philip Yuk Kwong Yung, Carmen Navarro, Adriano Bolondi, Abhishek Sampath Kumar, Chiara Anania, Björn Brändl, David Meierhofer, Darío G. Lupiáñez, Franz-Josef Müller, Tugce Aktas, Simon J. Elsässer, Helene Kretzmer, Zachary D. Smith, Alexander Meissner
Dynamic antagonism between key repressive pathways maintains the placental epigenome
Nature Cell Biology volume 25 (2023)
5.
Vahid Asimi, Abhishek Sampath Kumar, Henri Niskanen, Christina Riemenschneider, Sara Hetzel, Julian Naderi, Nina Fasching, Niko Popitsch, Manyu Du, Helene Kretzmer, Zachary D. Smith, Raha Weigert, Maria Walther, Sainath Mamde, David Meierhofer, Lars Wittler, René Buschow, Bernd Timmermann, Ibrahim I. Cisse, Stefan L. Ameres, Alexander Meissner, Denes Hnisz
Hijacking of transcriptional condensates by endogenous retroviruses
Nature Genetics volume 54 (2022)
6.
Daniel Andergassen, Zachary D Smith, Helene Kretzmer, John L Rinn, Alexander Meissner
Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages
Developmental Cell 2021
7.
Hongcang Gu, Ayush T. Raman, Xiaoxue Wang, Federico Gaiti, Ronan Chaligne, Arman W. Mohammad, Aleksandra Arczewska, Zachary D. Smith, Dan A. Landau, Martin J. Aryee, Alexander Meissner, Andreas Gnirke
Smart-RRBS for single-cell methylome and transcriptome analysis
Nature Protocols volume 16 (2021)
8.
Stefanie Grosswendt, Helene Kretzmer, Zachary D. Smith, Abhishek Sampath Kumar, Sara Hetzel, Lars Wittler, Sven Klages, Bernd Timmermann, Shankar Mukherji, Alexander Meissner
Epigenetic regulator function through mouse gastrulation
Nature volume 584 (2020)
9.
Jocelyn Charlton, Eunmi J. Jung, Alexandra L. Mattei, Nina Bailly, Jing Liao, Eric J. Martin, Pay Giesselmann, Björn Brändl, Elena K. Stamenova, Franz-Josef Müller, Evangelos Kiskinis, Andreas Gnirke, Zachary D. Smith, Alexander Meissner
TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers
Nature Genetics volume 52 (2020)
10.
Sudhir Thakurela, Camille Sindhu, Evgeny Yurkovsky, Christina Riemenschneider, Zachary D. Smith, Iftach Nachman, Alexander Meissner
Differential regulation of OCT4 targets facilitates reacquisition of pluripotency
Nature Communications volume 10 (2019)