Publications

Balaskas, A.; Kraus, I.; Özgüldez, H. Ö.; Akbari-Omgba, P.; Buschow, R.; Berlad, I.; Hanna, J. H.; Kretzmer, H.; Bulut-Karslioglu, A.; Bolondi, A.: An advanced head-to-tail mouse embryo model with hypoxia-mediated neural patterning. bioRxiv (2025)

MPG.PuRe

Chudzik, K.; Guerreiro, I.; Kefalopoulou, S.; Abraham, A.; Schindler, M.; Ringel, A. R.; Nicodemi, M.; Chiariello, A. M.; Mundlos, S.; Kind, J. et al.; Robson, M. I.: Reconfiguration of genome-lamina interactions marks the commissioning of limb cell-fates. bioRxiv (2025)

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Swanepoel, C. M.; Wang, G.; Zhang, L.; Brändl, B.; Bauer, H.; Tsaytler, P.; Müller, F.-J.; Herrmann, B. G.; Mueller , J. L.: Acquisition of ampliconic sequences marks a selfish mouse t-haplotype. bioRxiv (2025)

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Jakobson, C. M.; Hartl , J.; Trébulle, P.; Mülleder, M.; Jarosz , D. F.; Ralser, M.: A genome-to-proteome atlas charts natural variants controlling proteome diversity and forecasts their fitness effects. bioRxiv (2024)

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Schindler, M.; Feregrino, C.; Aldrovandi, S.; Lo, B.-W.; Monaco, A. A.; Ringel, A. R.; Morales, A.; Zehnder, T.; Behncke, R. Y.; Glaser, J. et al.; Barclay, A.; Andrey, G.; Kragesteen, B. K.; Hägerling, R.; Haas, S.; Vingron, M.; Ulitsky, I.; Marti-Renom, M.; Hechavarria, J.; Fasel, P.; Hiller, M.; Lupiáñez, D.; Mundlos, S.; Real, F. M.: Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene program in bat wing development. bioRxiv: the preprint server for biology (2024)

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Schwaemmle, T.; Noviello, G.; Kanata, E.; Froehlich, J. J.; Bothe, M.; Altay, A.; Scouarnec, J.; Feng, V.-Y.; Vingron, M.; Schulz, E. G.: Reporter CRISPR screens decipher cis- and trans-regulatory principles at the Xist locus. bioRxiv (2024)

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Glaser, J.; Cova, G.; Fauler, B.; Prada-Medina, C. A.; Stanislas, V.; Phan, M. H. Q.; Schöpflin, R.; Aktas, Y.; Franke, M.; Andrey, G. et al.; Paliou, C.; Laupert, V.; Chan, W.-L.; Wittler, L.; Mielke, T.; Mundlos, S.: Enhancer adoption by an LTR retrotransposon generates viral-like particles causing developmental limb phenotypes. bioRxiv (2024)

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Guckelberger, P.; Doughty, B. R.; Munson, G.; Rao, S. S. P.; Tan, Y.; Cai, X. S.; Fulco, C. P.; Nasser, J.; Mualim, K. S.; Bergman, D. T. et al.; Ray, J.; Jagoda, E.; Munger, C. J.; Gschwind, A. R.; Sheth, M. U.; Tan, A. S.; Pulido, S. G.; Mitra, N.; Weisz, D.; Shamim, M. S.; Durand, N. C.; Mahajan, R.; Khan, R.; Steinmetz, L. M.; Kanemaki, M. T.; Lander, E. S.; Meissner, A.; Lieberman Aiden, E.; Engreitz, J. M.: Cohesin-mediated 3D contacts tune enhancer-promoter regulation. bioRxiv (2024)

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Zagoren, E.; Dias, N.; Smith, Z. D.: A second wave of Notch signaling diversifies the intestinal secretory lineage. bioRxiv (2024)

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Phan, M. H. Q.; Zehnder, T.; Puntieri, F.; Lo, B.-W.; Lenhard, B.; Mueller, F.; Vingron, M.; Ibrahim, D. M.: Conservation of Regulatory Elements with Highly Diverged Sequences Across Large Evolutionary Distances. bioRxiv (2024)

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Mutzel, V.; Schwämmle, T.; Oeverdieck, S.; Librenjak, L.; Boesen, B.; Bothe, M.; Gjaltema, R. A. F.; Dunkel, I.; Noviello, G.; Schulz, E. G.: Antisense transcription can induce expression memory via stable promoter repression. bioRxiv (2024)

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Kaur Aulakh, S.; Lemke, O.; Szyrwiel, L.; Kamrad, S.; Chen, Y.; Hartl, J.; Muelleder, M.; Nielsen, J.; Ralser, M.: The molecular landscape of cellular metal ion biology. bioRxiv (2024)

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Kӧvér, B.; Cohen, C. E.; Ralser, M.: Genetic and environmental determinants of multicellular-like phenotypes in fission yeast. bioRxiv (2023)

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Schmidt, D.; Duport, Y.; Kollan, C.; Marcus, U.; Iannuzzi, S.; von Kleist, M.: Dynamics of HIV PrEP use and coverage during and after COVID-19 in Germany. SSRN eLibrary (2023)

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Basu, S.; Martínez-Cristóbal, P.; Pesarrodona, M.; Frigolé-Vivas, M.; Szulc, E.; Lewis, M.; Bañuelos, C. A.; Sánchez-Zarzalejo, C.; Bielskutė, S.; Zhu, J. et al.; Garcia-Cabau, C.; Batlle, C.; Mateos, B.; Biesaga, M.; Escobedo, A.; Bardia, L.; Verdaguer, X.; Ruffoni, A.; Mawji, N. R.; Wang, J.; Tam, T.; Brun-Heath, I.; Ventura, S.; Meierhofer, D.; García, J.; Robustelli, P.; Stracker, T. H.; Sadar, M. D.; Riera, A.; Hnisz, D.; Salvatella, X.: Androgen receptor condensates as drug targets. bioRxiv (2022)

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Graziadei, A.; Schildhauer, F.; Spahn, C.; Kraushar, M.; Rappsilber, J.: SARS-CoV-2 Nsp1 N-terminal and linker regions as a platform for host translational shutoff. bioRxiv (2022)

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Ambrozkiewicz, M. C.; Borisova, E.; Newman, A. G.; Kraushar, M.; Schaub, T.; Dannenberg, R.; Brockmann, M.; Rosário, M.; Turko, P.; Jahn, O. et al.; Kaplan, D. R.; Iwawaki, T.; Spahn, C. M. T.; Rosenmund, C.; Tarabykin, V.: Ire1a-Regulated mRNA Translation Rate Controls the Identity and Polarity of Upper Layer Cortical Neurons. bioRxiv (2022)

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Ambrozkiewicz, M. C.; Borisova, E.; Newman, A. G.; Kraushar, M. L.; Schaub, T.; Dannenberg, R.; Brockmann, M.; Rosário, M.; Turko, P.; Jahn, O. et al.; Kaplan, D. R.; Iwawaki, T.; Spahn, C. M. T.; Rosenmund, C.; Tarabykin, V.: Ire1α-Regulated Rate of mRNA Translation is Required for Acquisition of Identity and Polarity in Upper Layer Cortical Neurons. bioRxiv (2021)

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Smajić, S.; Prada-Medina, C. A.; Landoulsi, Z.; Dietrich, C.; Jarazo, J.; Henck, J.; Balachandran, S.; Pachchek, S.; Morris, C. M.; Antony, P. et al.; Timmermann, B.; Sauer, S.; Schwamborn, J. C.; May, P.; Grünewald, A.; Spielmann, M.: Single-cell sequencing of the human midbrain reveals glial activation and a neuronal state specific to Parkinson’s disease. medRxiv (2020)

MPG.PuRe

Hogan, J. D.; Keenan, J. L.; Luo, L.; Hawkins, D. Y.; Ibn-Salem, J.; Lamba, A.; Schatzberg, D.; Piacentino, M. L.; Zuch, D. T.; Core, A. B. et al.; Blumberg, C.; Timmermann, B.; Grau, J. H.; Speranza, E.; Andrade-Narravo, M. A.; Irie, N.; Poustka, A. J.; Bradham, C. A.: The Developmental Transcriptome for Lytechinus variegatus Exhibits Temporally Punctuated Gene Expression Changes. Developmental Biology 460 (2), pp. 139 - 154 (2020)

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Lammel, D. R.; Meierhofer, D.; Johnston, P.; Mbedi, S.; Rillig, M. C.: The effects of arbuscular mycorrhizal fungi (AMF) and Rhizophagus irregularis on soil microorganisms assessed by metatranscriptomics and metaproteomics. bioRxiv (2019)

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Despang, A.; Schöpflin, R.; Franke, M.; Ali, S.; Jerkovic, I.; Paliou, C.; Chan, W.-L.; Timmermann, B.; Wittler, L.; Vingron, M. et al.; Mundlos, S.; Ibrahim, D. M.: Functional dissection of TADs reveals non-essential and instructive roles in regulating gene expression. bioRxiv (2019)

MPG.PuRe

Mutzel, V.; Okamoto, I.; Dunkel, I.; Saitou, M.; Giorgetti, L.; Heard, E.; Schulz, E. G.: Two coupled feedback loops explain random mono-allelic Xist upregulation at the onset of X-chromosome inactivation. bioRxiv: the preprint server for biology 2017, pp. 1 - 54 (2017)

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Published

2025

Review Article

Ilik, I. A.; Yang, X.; Zhang, Z. Z.; Aktas, T.: Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease. Nature Reviews Molecular Cell Biology (2025)

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Journal Article

Zhang, Y.; Stöppelkamp, I.; Fernandez-Pernas, P.; Allram, M.; Charman, M.; Magalhães, A. P.; Piedavent-Salomon, M.; Sommer, G.; Sung, Y.-C.; Meyer, K. et al.; Grams, N.; Halko, E.; Dongre, S.; Meierhofer, D.; Malszycki, M.; Ilik, I. A.; Aktas, T.; Kraushar, M. L.; Vastenhouw, N.; Weitzman, M. D.; Grebien, F.; Niskanen, H.; Hnisz, D.: Probing condensate microenvironments with a micropeptide killswitch. Nature (2025)

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Journal Article

Martina, L.; Malszycki, M.; Aktas, T.: Distinct states of Nuclear Speckles emerge as new predictors of cancer prognosis. Cancer Research 85 (8), pp. 1352 - 1353 (2025)

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2024

Journal Article

Stötzel, M.; Cheng, C.-Y.; Ilik, I. A.; Sampath Kumar, A.; Akbari-Omgba, P.; van der Weijden, V. A.; Zhang, Y.; Vingron, M.; Meissner, A.; Aktas, T. et al.; Kretzmer, H.; Bulut-Karslioglu, A.: TET activity safeguards pluripotency throughout embryonic dormancy. Nature Structural & Molecular Biology 31 (10), pp. 1625 - 1639 (2024)

MPG.PuRe

Journal Article

Kellner, M.; Hörmann, J.; Fackler, S.; Yuanyu, H.; Tielin, Z.; Lin, L.; Ilik, I.; Aktas, T.; Feederle, R.; Hauck, S. M. et al.; Gires, O.; Gärtner, K.; Lietao, L.; Zeidler, R.: The Nuclear Speckles Protein SRRM2 Is Exposed on the Surface of Cancer Cells. Cells 13 (18), Article 1563 (2024)

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Journal Article

Lisowski, P.; Lickfett, S.; Rybak-Wolf, A.; Menacho, C.; Le, S.; Pentimalli, T. M.; Notopoulou, S.; Dykstra, W.; Oehler, D.; López-Calcerrada, S. et al.; Mlody, B.; Otto, M.; Wu, H.; Richter, Y.; Roth, P.; Anand, R.; Kulka, L. A. M.; Meierhofer, D.; Glazar, P.; Legnini, I.; Telugu, N. S.; Hahn, T.; Neuendorf, N.; Miller, D. C.; Böddrich, A.; Polzin, A.; Mayatepek, E.; Diecke, S.; Olzscha, H.; Kirstein, J.; Ugalde, C.; Petrakis, S.; Cambridge, S.; Rajewsky, N.; Kühn, R.; Wanker, E. E.; Priller, J.; Metzger, J. J.; Prigione, A.: Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure. Nature Communications 15 (1), Article 7027 (2024)

MPG.PuRe

Journal Article

Ilik, I. A.; Glažar, P.; Tse, K.; Brändl, B.; Meierhofer, D.; Müller, F.-J.; Smith, Z. D.; Aktas, T.: Autonomous transposons tune their sequences to ensure somatic suppression. Nature 626 (8001), pp. 1116 - 1124 (2024)

MPG.PuRe

2023

Journal Article

Weigert, R.; Hetzel, S.; Bailly, N.; Haggerty, C.; Ilik, I. A.; Kwong Yung, P. Y.; Navarro, C.; Bolondi, A.; Sampath Kumar, A.; Anania, C. et al.; Brändl, B.; Meierhofer, D.; Lupiáñez, D. G.; Müller, F.-J.; Aktas, T.; Elsässer, S. J.; Kretzmer, H.; Smith, Z. D.; Meissner, A.: Dynamic antagonism between key repressive pathways maintains the placental epigenome. Nature Cell Biology 25 (4), pp. 579 - 591 (2023)

MPG.PuRe

2022

Review Article

Ilik, I. A.; Aktas, T.: Nuclear speckles: dynamic hubs of gene expression regulation. The FEBS Journal 289 (22), pp. 7234 - 7245 (2022)

MPG.PuRe

Journal Article

Bergfort, A.; Hilal, T.; Kuropka, B.; Ilik, I. A.; Weber, G.; Aktas, T.; Freund, C.; Wahl, M. C.: The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Research (London) 50 (5), pp. 2938 - 2958 (2022)

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Journal Article

Aktas, T.: Transposons: catch them if you can. Nature Reviews Molecular Cell Biology 23 (5), 306 (2022)

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Journal Article

Bergfort, A.; Preußner, M.; Kuropka, B.; Ilik, I. A.; Hilal, T.; Weber, G.; Freund, C.; Aktas, T.; Heyd, F.; Wahl, M. C.: A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing. Nature Communications 13 (1), Article 1132 (2022)

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2020

Journal Article

Ilik, I. A.; Malszycki, M.; Lübke, A. K.; Schade, C.; Meierhofer, D.; Aktas, T.: SON and SRRM2 are essential for nuclear speckle formation. eLife 9, Article e60579 (2020)

MPG.PuRe

Journal Article

Ilik, I. A.; Aktas, T.; Maticzka, D.; Backofen, R.; Akhtar, A.: FLASH: ultra-fast protocol to identify RNA-protein interactions in cells. Nucelic Acids Research 48 (3), Article e15 (2020)

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ZIP

Publications by Firstname Lastname before 20nm [year before MPIMG affiliation]

MPG.PuRe