Publications

The following publications were published exclusively under the affiliation of the Max Planck Society. For publications by the principal investigator outside of the Max Planck Society, see the links on the lower left.

Journal Article (56)

Journal Article
Lazaro-Navarro, J.; Alcon, C.; Dorel, M.; Alasfar, L.; Bastian, L.; Baldus, C.; Astrahantseff, K.; Yaspo, M.-L.; Montero, J.; Eckert, C.: Inhibiting H3K27 Demethylases Downregulates CREB-CREBBP, Overcoming Resistance in Relapsed Acute Lymphoblastic Leukemia. Cancer Medicine 14 (1), pp. 1 - 7 (2025)
Journal Article
Bortolini Silveira, A.; Houy, A.; Ganier, O.; Özemek, B.; Vanhuele, S.; Vincent-Salomon, A.; Cassoux, N.; Mariani , P.; Pierron, G.; Leyvraz, S. et al.; Rieke, D.; Picca, A.; Bielle, F.; Yaspo, M.-L.; Rodrigues, M.; Stern, M.-H.: Base-excision repair pathway shapes 5-methylcytosine deamination signatures in pan-cancer genomes. Nature Communications 15 (1), Article 9864 (2024)
Journal Article
Künzel, S. E.; Frentzel, D. P.; Flesch, L. T. M.; Knecht, V. A.; Rübsam, A.; Dreher, F.; Schütte, M.; Dubrac, A.; Lange, B.; Yaspo, M.-L. et al.; Lehrach, H.; Joussen, A. M.; Zeitz, O.: AI-driven discovery of blood xenobiotic biomarkers in neovascular age-related macular degeneration using iterative random forests. Graefe's Archive for Clinical and Experimental Ophthalmology 262 (11), pp. 3567 - 3575 (2024)
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Künzel, S. E.; Pompös, I.-M.; Flesch, L. T. M.; Frentzel, D. P.; Knecht, V. A.; Winkler, S.; Skosyrski, S.; Rübsam, A.; Dreher, F.; Kociok, N. et al.; Schütte, M.; Dubrac, A.; Lange, B.; Yaspo, M.-L.; Lehrach, H.; Strauß, O.; Joussen, A. M.; Zeitz, O.: Exploring the Impact of Saccharin on Neovascular Age-Related Macular Degeneration: A Comprehensive Study in Patients and Mice. Investigative Ophthalmology and Visual Science 65 (4), Article 5 (2024)
Journal Article
Sultana, Z.; Dorel, M.; Klinger, B.; Sieber, A.; Dunkel, I.; Blüthgen, N.; Schulz, E. G.: Modeling unveils sex differences of signaling networks in mouse embryonic stem cells. Molecular Systems Biology 19 (11), e11510 (2023)
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Ng, M.; Verboon, L.; Issa, H.; Bhayadia, R.; Vermunt, M. W.; Winkler, R.; Schüler, L.; Alejo, O.; Schuschel, K.; Regenyi, E. et al.; Borchert, D.; Heuser, M.; Reinhardt, D.; Yaspo, M.-L.; Heckl, D.; Klusmann, J.-H.: Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15. iScience 26 (10), 107844 (2023)
Journal Article
Gialesaki , S.; Bräuer-Hartmann , D.; Issa, H.; Bhayadia, R.; Alejo-Valle, O.; Verboon, L.; Schmell, A.-L.; Laszig, S.; Regenyi, E.; Schuschel, K. et al.; Labuhn , M.; Ng, M.; Winkler , R.; Ihling, C.; Sinz, A.; Glaß, M.; Hüttelmaier, S.; Matzk, S.; Schmid, L.; Strüwe, F.; Kadel, S.-K.; Reinhardt, D.; Yaspo, M.-L.; Heckl, D.; Klusmann, J.-H.: RUNX1 isoform disequilibrium promotes the development of trisomy 21 associated myeloid leukemia. Blood 141 (10), pp. 1105 - 1118 (2022)
Journal Article
Leyvraz, S.; Konietschke, F.; Peuker, C.; Schütte, M.; Kessler, T.; Ochsenreither, S.; Ditzhaus, M.; Sprünken, E. D.; Dörpholz, G.; Lamping, M. et al.; Rieke, D. T.; Klinghammer, K.; Burock, S.; Ulrich, C.; Poch, G.; Schäfer, R.; Klauschen, F.; Joussen, A.; Yaspo, M.-L.; Keilholz, U.: Biomarker-driven therapies for metastatic uveal melanoma: A prospective precision oncology feasibility study. European Journal of Cancer 169, pp. 146 - 155 (2022)
Journal Article
Berlak, M.; Tucker, E.; Dorel, M.; Winkler, A.; McGearey, A.; Rodriguez-Fos, E.; Martins da Costa, B.; Barker, K.; Fyle, E.; Calton, E. et al.; Eising, S.; Ober, K.; Hughes, D.; Koutroumanidou, E.; Carter, P.; Stankunaite, R.; Proszek, P.; Jain, N.; Rosswog, C.; Dorado-Garcia, H.; Molenaar, J. J.; Hubank, M.; Barone, G.; Anderson, J.; Lang, P.; Deubzer, H. E.; Künkele, A.; Fischer, M.; Eggert, A.; Kloft, C.; Henssen, A. G.; Boettcher, M.; Hertwig, F.; Blüthgen, N.; Chesler, L.; Schulte, J. H.: Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells. Molecular Cancer 21, 126 (2022)
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Vuaroqueaux, V.; Musch, A.; Kobelt, D.; Risch, T.; Herrmann, P.; Burock, S.; Peille, A.-L.; Yaspo, M.-L.; Fiebig, H.-H.; Stein, U.: Elevated MACC1 Expression in Colorectal Cancer Is Driven by Chromosomal Instability and Is Associated with Molecular Subtype and Worse Patient Survival. Cancers / Molecular Diversity Preservation International (MDPI) 14 (7), 1749 (2022)
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Alejo-Valle, O.; Weigert, K.; Bhayadia, R.; Ng, M.; Issa, H.; Beyer, C.; Emmrich, S.; Schuschel, K.; Ihling, C.; Sinz, A. et al.; Zimmermann, M.; Wickenhauser, C.; Flasinski, M.; Regenyi, E.; Labuhn, M.; Reinhardt, D.; Yaspo, M.-L.; Heckl, D.; Klusmann, J.-H.: The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis. Blood 139 (5), pp. 651 - 665 (2022)
Journal Article
Keil, M.; Conrad, T.; Becker, M.; Keilholz, U.; Yaspo, M.-L.; Lehrach, H.; Schütte, M.; Haybaeck, J.; Hoffmann, J.: Modeling of Personalized Treatments in Colon Cancer Based on Preclinical Genomic and Drug Sensitivity Data. Cancers 13 (23), 6018 (2021)
Journal Article
Xiao, Y.; Rabien, A.; Buschow, R.; Amstislavskiy, V.; Busch, J.; Kilic, E.; Villegas, S. L.; Timmermann, B.; Schütte, M.; Mielke, T. et al.; Yaspo, M.-L.; Jung, K.; Meierhofer, D.: Endocytosis-mediated replenishment of amino acids favors cancer cell proliferation and survival in chromophobe renal cell carcinoma. Cancer research: an official organ of the American Association for Cancer Research 80, pp. 5491 - 5501 (2020)
Journal Article
Bornhauser, B.; Cario, G.; Rinaldi, A.; Risch, T.; Rodriguez Martinez, V.; Schütte, M.; Warnatz, H.-J.; Scheidegger, N.; Mirkowska, P.; Temperli, M. et al.; Möller, C.; Schumich, A.; Dworzak, M.; Attarbaschi, A.; Brüggemann, M.; Ritgen, M.; Mejstrikova, E.; Hofmann, A.; Buldini, B.; Scarparo, P.; Basso, G.; Maglia, O.; Gaipa, G.; Skoblyn, T.-L.; Te Kronnie, G.; Vendramini, E.; Panzer-Grümayer, R.; Barz, M. J.; Marovca, B.; Hauri-Hohl, M.; Niggli, F.; Eckert, C.; Schrappe, M.; Stanulla, M.; Zimmermann, M.; Wollscheid, B.; Yaspo, M.-L.; Bourquin, J.-P.: The hematopoietic stem cell marker VNN2 is associated with chemoresistance in pediatric B-cell precursor ALL. Blood Advances 4 (17), pp. 4052 - 4064 (2020)
Journal Article
Burns, M.; Schulz, A. R.; Kunkel, D.; Hönig, M.; Warth, S.; Bengsch, B.; Burns, T.; Reinhardt, J.; Grützkau, A.; Yaspo, M.-L. et al.; Sodenkamp, J.; Hoffmann, U.; Mei, H. E.: Mass Cytometry-A Tool for the Curious: Networking in Berlin. Cytometry Part A 97 (8), pp. 764 - 767 (2020)
Journal Article
Lampignano , R.; Neumann, M. H.D.; Weber, S.; Kloten, V.; Herdean, A.; Voss, T.; Groelz, D.; Babayan, A.; Tibbesma, M.; Schlumpberger, M. et al.; Chemi, F.; Rothwell, D. G.; Wikman, H.; Galizzi, J.-P.; Bergheim, I. R.; Russnes, H.; Mussolin, B.; Bonin, S.; Voigt, C.; Musa, H.; Pinzani, P.; Lianidou, E.; Brady, G.; Speicher, M. R.; Pantel, K.; Betsou, F.; Schuuring, E.; Kubista, M.; Ammerlaan, W.; Sprenger-Haussels, M.; Schlange, T.; Heitzer, E.; Lehrach, H.; Yaspo, M.-L.: Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows. Clinical Chemistry: International Journal of Molecular Diagnostics and Laboratory Medicine 66 (1), pp. 149 - 160 (2020)
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Huang, Y.; Mouttet , B.; Warnatz, H.-J.; Risch, T.; Rietmann, F.; Frommelt, F.; Ngo, Q. A.; Dobay, M. P.; Marovca, B.; Jenni, S. et al.; Tsai, Y.-C.; Matzk, S.; Amstislavskiy, V.; Schrappe, M.; Stanulla, M.; Gstaiger, M.; Bornhauser, B.; Yaspo, M.-L.; Bourquin , J.-P.: The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability. Cancer Cell 36 (6), pp. 630 - 644 (2019)
Journal Article
Schade, S.; Ogilvie, L. A.; Kessler, T.; Schütte, M.; Wierling, C.; Lange, B. M.; Lehrach, H.; Yaspo, M.-L.: A data- and model-driven approach for cancer treatment. Der Onkologe 25 (Suppl. 2), pp. S132 - S137 (2019)
Journal Article
Labuhn, M.; Perkins, K.; Matzk, S.; Varghese, L.; Garnett, C.; Papaemmanuil, E.; Metzner, M.; Kennedy, A.; Amstislavskiy, V.; Risch, T. et al.; Bhayadia, R.; Samulowski, D.; Hernandez, D. C.; Stoilova, B. ....; Yaspo, M.-L.; Campbell, P. J.; Roberts, I.; Constantinescu, S. N.; Vyas, P.; Heckl, D.; Klusmann, J.-H.: Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome. Cancer Cell 36 (2), pp. 123 - 138 (2019)
Journal Article
Schade, S.; Ogilvie, L. A.; Kessler, T.; Schütte, M.; Wierling, C.; Lange, B. M.; Lehrach, H.; Yaspo, M.-L.: Ein daten- und modellgesteuerter Ansatz zur Behandlung maligner Tumoren. Der Onkologe 25 (Suppl. 1), pp. S109 - S115 (2019)
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