Lab News

The architecture of shattered genomes

Hunting for disease clues in the dark matter of our DNA more

Illustration showing a tangle of DNA helices and triangular shapes, one of which is breaking up into pieces

Layers of gene control allow DNA to flexibly add new information more

Portrait of Prof. Stefan Mundlos

The genomics of evolution: how bats learned to fly more

Leopoldina honors human geneticist Stefan Mundlos

Researcher receives Mendel Medal for findings on gene regulation and genetic skeletal malformations more

Reading between the lines of the genome

Congenital malformation caused by a so far unknown disease mechanism more

Intelligence deficit: Conclusions drawn from mouse to man

New animal model for GPI anchor deficiencies more

Moles: intersexual and genetically doped

Duplications and inversions of DNA segments lead to the masculinization of female moles more

Better recognition of chromosomal diseases

Hi-C method improves detection of breaks and rearrangements in the genome more

Unexpectedly potent protein droplets

Berlin researchers discover new pathomechanism of hereditary diseases in cell condensates more

“There is no reason for germline therapy”

Stefan Mundlos, from the Max Planck Institute for Molecular Genetics, explains why there will be no designer babies in the near future more

What’s important?

What’s important?

August 08, 2019

Formation of the 3D structure and specific interaction between genes and enhancers represent independent layers of gene regulation more

Decoding Lil BUB

Decoding Lil BUB

March 04, 2019

Crowdfunded project reveals genome of internet celebrity cat more

Stripes in the genome

Stripes in the genome

February 12, 2019

Scientists at the Max Planck Institute for Molecular Genetics describe tissue-specific formation of architectural stripes driven by enhancer activity and CTCF elements more

Chromatin structure mutes enhancer activity

Dynamic changes in the structure of chromatin controls the development of arms and legs more

Scientists from Berlin and Naples develop methods for predictions about the three-dimensional structure of DNA more

<p>Human geneticist Stefan Mundlos appointed External Scientific Member of the Max Planck Institute for Molecular Genetics</p>

Stefan Mundlos, director of the Institute for Medical Genetics and Human Genetics at the Charité - Universitätsmedizin Berlin and head of the research group "Development & Disease" at the Max Planck Institute for Molecular Genetics (MPIMG) in Berlin, has been appointed as External Scientific Member of the MPIMG by the Senate of the Max Planck Society (MPG). Thereby, the Max Planck Society honors the outstanding scientific achievements of Stefan Mundlos and the long-standing and very fruitful cooperation between the Charité and the Berlin-based institute. more

New gene functions after genomic duplications

Researchers in Berlin describe how duplications of DNA segments affect the three dimensional structure of the genome more

Stefan Mundlos has given this year’s ESHG Award Lecture more

“No authorization exists for such research”

The human geneticist Stefan Mundlos warns against intervention in the human germline made possible by the CRISPR/Cas ‘gene scissors’ more

Genetic diseases shift boundaries within the genome

Researchers in Berlin find that some rare diseases are caused by the destruction of functional boundaries within DNA more

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