Publications

Neureiter, A.; Brändl, B.; Hiber, M.; Tandon, R.; Müller, F.-J.; Steenpass, L.: Generation of an iPSC line of a patient with Angelman syndrome due to an imprinting defect. Stem Cell Research 33, pp. 20 - 24 (2018)

Tandon, R.; Brändl, B.; Baryshnikova, N.; Landshammer, A.; Steenpaß, L.; Keminer, O.; Pless, O.; Müller, F.-J.: Generation of two human isogenic iPSC lines from fetal dermal fibroblasts. Stem Cell Research 33, pp. 120 - 124 (2018)

Zhang, Y.; Charlton, J.; Karnik, R.; Beerman, I.; Smith, Z. D.; Gu, H.; Boyle, P.; Mi , X.; Clement, K.; Pop, R. et al.; Gnirke, A.; Rossi, D. J.; Meissner, A.: Targets and genomic constraints of ectopic Dnmt3b expression. eLife 7, e40757 (2018)

Ichida, J. K.; Staats, K. A.; Davis-Dusenbery, B. N.; Clement, K.; Galloway, K. E.; Babos, K. N.; Shi, Y.; Son, E. Y.; Kiskinis, E.; Atwater, N. et al.; Gu, H.; Gnirke, A.; Meissner, A.; Eggan, K.: Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons. Development 145 (22), pii: dev168617 (2018)

Bernstein, E.; Meissner, A.; Ramalho-Santos, M.: Paying PIs from grants blocks talent and diversity. Nature 563 (7731), p. 325 (2018)

Rajavelu, A.; Lungu, C.; Emperle, M.; Dukatz, M.; Bröhm, A.; Broche, J.; Hanelt, I.; Parsa, E.; Schiffers, S.; Karnik, R. et al.; Meissner, A.; Carell, T.; Rathert, P.; Jurkowska, R. Z.; Jeltsch, A.: Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2. Nucleic Acids Research (London) 46 (17), pp. 9044 - 9056 (2018)

Cacchiarelli, D.; Qiu, X.; Srivatsan, S.; Manfredi, A.; Ziller, M.; Overbey, E.; Grimaldi, A.; Grimsby, J.; Pokharel, P.; Livak, K. J. et al.; Li, S.; Meissner, A.; Mikkelsen, T. S.; Rinn, J. L.; Trapnell, C.: Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome. Cell Systems 7 (3), pp. 258 - 268 (2018)

Di Stefano, B.; Ueda, M.; Sabri, S.; Brumbaugh, J.; Huebner, A. J.; Sahakyan, A.; Clement, K.; Clowers, K. J.; Erickson, A. R.; Shioda, K. et al.; Gygi, S. P.; Gu, H.; Shioda, T.; Meissner, A.; Takashima, Y.; Plath, K.; Hochedlinger, K.: Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells. Nature methods 15 (9), pp. 732 - 740 (2018)

Schwarz, B. A.; Cetinbas, M.; Clement, K.; Walsh, R. M.; Cheloufi, S.; Gu, H.; Langkabel, J.; Kamiya, A.; Schorle, H.; Meissner, A. et al.; Sadreyev, R. I.; Hochedlinger, K.: Prospective Isolation of Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming. Cell Stem Cell 23 (2), pp. 289 - 305 (2018)

Sabari, B. R.; Dall’Agnese, A.; Boija, A.; Klein, I. A.; Coffey, E. L.; Shrinivas, K.; Abraham, B. J.; Hannett, N. M.; Zamudio, A. V.; Manteiga, J. C. et al.; Li, C. H.; Guo, Y. E.; Day, D. S.; Schuijers, J.; Vasile, E.; Malik, S.; Hnisz, D.; Lee, T. I.; Cisse, I. I.; Roeder, R. G.; Sharp, P. A.; Chakraborty, A. K.; Young, R. A.: Coactivator condensation at super-enhancers links phase separation and gene control. Science (6400), eaar3958 (2018)

Percharde, M.; Lin, C.-J.; Yin, Y.; Guan, J.; Peixoto, G. A.; Bulut-Karslioglu, A.; Biechele, S.; Huang, B.; Shen, X.; Ramalho-Santos, M.: A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity. Cell 174 (2), pp. 391 - 405 (2018)

Nehme, R.; Zuccaro, E.; Ghosh, S. D.; Li, C.; Sherwood, J. L.; Pietilainen, O.; Barrett, L. E.; Limone, F.; Worringer, K. A.; Kommineni, S. et al.; Zang, Y.; Cacchiarelli, D.; Meissner, A.; Adolfsson, R.; Haggarty, S.; Madison, J.; Muller, M.; Arlotta, P.; Fu, Z.; Feng, G.; Eggan, K.: Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. Cell Reports 23 (8), pp. 2509 - 2523 (2018)

Allison, T. F.; Andrews, P. W.; Avior, Y.; Barbaric, I.; Benvenisty, N.; Bock, C.; Brehm, J.; Bruestle, O.; Damjanov, I.; Elefanty, A. et al.; Felkner, D.; Gokhale, P. J.; Halbritter, F.; Healy, L. E.; Hu, T. X.; Knowles, B. B.; Loring, J. F.; Ludwig, T. E.; Mayberry, R.; Micallef, S.; Mohamed, J. S.; Müller, F.-J.; Mummery, C. L.; Nakatsuji, N.; Ng, E. S.; Oh, S. K. W.; O'Shea, O.; Pera, M. F.; Reubinoff, B.; Robson, P.; Rossant, J.; Schuldt, B. M.; Solter, D.; Sourris, K.; Stacey, G.; Stanley, E. G.; Suemori, H.; Takahashi, K.; Yamanaka, S.: Assessment of Established Techniques to Determine Developmental and Malignant Potential of Human Pluripotent Stem Cells. Nature Communications 9 (1), 1925 (2018)

Pasque, V.; Karnik, R.; Chronis, C.; Petrella, P.; Langerman, J.; Bonora, G.; Song, J.; Vanheer, L.; Dimashkie, A. S.; Meissner, A. et al.; Plath, K.: X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs. Stem Cell Reports 10 (5), pp. 1537 - 1550 (2018)

Shukla, S. A.; Bachireddy, P.; Schilling, B.; Galonska, C.; Zhan, Q.; Bango, C.; Langer, R.; Lee, P. C.; Gusenleitner, D.; Keskin, D. B. et al.; Babadi, M.; Mohammad, A.; Gnirke, A.; Clement, K.; Cartun, Z. J.; Van Allen, E. M.; Miao, D.; Huang, Y.; Snyder, A.; Merghoub, T.; Wolchok, J. D.; Garraway, L. A.; Meissner, A.; Weber, J. S.; Hacohen, N.; Neuberg, D.; Potts, P. R.; Murphy, G. F.; Lian, C. G.; Schadendorf, D.; Hodi, F. S.; Wu, C. J.: Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade. Cell 173 (3), pp. 624 - 633 (2018)

Schuijers, J.; Manteiga, J. C.; Weintraub, A. S.; Day, D. S.; Zamudio, A. V.; Hnisz, D.; Lee, T. I.; Young, R. A.: Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism. Cell Reports 23 (2), pp. 349 - 360 (2018)

Cesana, M.; Guo, M. H.; Cacchiarelli, D.; Wahlster, L.; Barragan, J.; Doulatov, S.; Vo, L. T.; Salvatori, B.; Trapnell, C.; Clement, K. et al.; Cahan, P.; Tsanov, K. M.; Sousa, P. M.; Tazon-Vega, B.; Bolondi, A.; Giorgi, F. M.; Califano, A.; Rinn, J. L.; Meissner, A.; Hirschhorn, J. N.; Daley, G. Q.: A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. Cell Stem Cell 22 (4), pp. 575 - 588 (2018)

Vögtle, F.-N.; Brändl, B.; Larson, A.; Pendziwiat, M.; Friederich, M. W.; White, S. M.; Basinger, A.; Kücükköse, C.; Muhle, H.; Jähn, J. A. et al.; Keminer, O.; Helbig, K. L.; Delto, C. F.; Myketin, L.; Mossmann, D.; Burger, N.; Miyake, N.; Burnett, A.; van Baalen, A.; Lovell, M. A.; Matsumoto, N.; Walsh, M.; Yu, H.-C.; Deepali N. Shinde, D. N.; Stephani, U.; Van Hove, J. L. K.; Müller, F.-J.; Helbig, I.: Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood. American Journal of Human Genetics 102 (4), pp. 557 - 573 (2018)

Ziller, M. J.; Ortega, J. A.; Quinlan, K. A.; Santos, D. P.; Gu, H.; Martin , E. J.; Galonska, C.; Pop, R.; Maidl, S.; Pardo, A. D. et al.; Huang , M.; Meltzer, H. Y.; Gnirke , A.; Heckman, C. J.; Meissner, A.; Kiskinis, E.: Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology. Cell Stem Cell 22, pp. 1 - 16 (2018)

Charlton, J.; Downing, T. L.; Smith, Z. D.; Gu, H.; Clement, K.; Pop, R.; Akopian, V.; Klages, S.; Santos, D. P.; Tsankov, A. M. et al.; Timmermann, B.; Ziller, M. J.; Kiskinis, E.; Gnirke, A.; Meissner, A.: Global delay in nascent strand DNA methylation. Nature Structural and Molecular Biology 25 (4), pp. 327 - 332 (2018)