Publications

Journal Article (21)

1. 1.
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   Kraft, K.; Magg, A.; Heinrich, V.; Riemenschneider, C.; Schöpflin, R.; Markowski, J.; Ibrahim, D.; Acuna-Hidalgo, R.; Despang, A.; Andrey, G. et al.; Wittler, L.; Timmermann, B.; Vingron, M.; Mundlos, S.: Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations. Nature Cell Biology 21 (3), pp. 305 - 310 (2019)
2. 2.
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   Vögtle, F.-N.; Brändl, B.; Larson, A.; Pendziwiat, M.; Friederich, M. W.; White, S. M.; Basinger, A.; Kücükköse, C.; Muhle, H.; Jähn, J. A. et al.; Keminer, O.; Helbig, K. L.; Delto, C. F.; Myketin, L.; Mossmann, D.; Burger, N.; Miyake, N.; Burnett, A.; van Baalen, A.; Lovell, M. A.; Matsumoto, N.; Walsh, M.; Yu, H.-C.; Deepali N. Shinde, D. N.; Stephani, U.; Van Hove, J. L. K.; Müller, F.-J.; Helbig, I.: Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood. American Journal of Human Genetics 102 (4), pp. 557 - 573 (2018)
3. 3.
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   Ziller, M. J.; Ortega, J. A.; Quinlan, K. A.; Santos, D. P.; Gu, H.; Martin , E. J.; Galonska, C.; Pop, R.; Maidl, S.; Pardo, A. D. et al.; Huang , M.; Meltzer, H. Y.; Gnirke , A.; Heckman, C. J.; Meissner, A.; Kiskinis, E.: Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology. Cell Stem Cell 22, pp. 1 - 16 (2018)
4. 4.
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   Charlton, J.; Downing, T. L.; Smith, Z. D.; Gu, H.; Clement, K.; Pop, R.; Akopian, V.; Klages, S.; Santos, D. P.; Tsankov, A. M. et al.; Timmermann, B.; Ziller, M. J.; Kiskinis, E.; Gnirke, A.; Meissner, A.: Global delay in nascent strand DNA methylation. Nature Structural and Molecular Biology 25 (4), pp. 327 - 332 (2018)
5. 5.
   MPG.PuRe

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   Galonska, C.; Charlton, J.; Mattei, A. L.; Donaghey, J.; Clement, K.; Gu, H.; Mohammad, A. W.; Stamenova, E. K.; Cacchiarelli, D.; Klages, S. et al.; Timmermann, B.; Cantz, T.; Schöler, H. R.; Gnirke, A.; Ziller, M. J.; Meissner, A.: Genome-wide tracking of dCas9-methyltransferase footprints. Nature Communications 9, 9:597 (2018)
6. 6.
   MPG.PuRe

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   Janssens, S.; Schotsaert, M.; Karnik, R.; Balasubramaniam, V.; Dejosez, M.; Meissner, A.; García-Sastre, A.; Zwaka, T. P.: Zika Virus Alters DNA Methylation of Neural Genes in an Organoid Model of the Developing Human Brain. mSystems 3 (1), e00219-17 (2018)
7. 7.
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   Donaghey, J.; Thakurela, S.; Charlton, J.; Chen, J. S.; Smith, Z. D.; Gu, H.; Pop, R.; Clement, K.; Stamenova, E. K.; Karnik, R. et al.; Kelley, D. R.; Gifford, C. A.; Cacchiarelli, D.; Rinn, J. L.; Gnirke, A.; Ziller, M. J.; Meissner, A.: Genetic determinants and epigenetic effects of pioneer-factor occupancy. Nature Genetics 2018 (2018)
8. 8.
   MPG.PuRe

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   Hu, H.; Kahrizi, K.; Musante, L.; Fattahi, Z.; Herwig, R.; Hosseini, M.; Oppitz, C.; Abedini, S. S.; Suckow, V.; Farzaneh, L. et al.; Beheshtian, M.; Lipkowitz, B.; Akhtarkhavari, T.; Mehvari, S.; Otto, S.; Mohseni, M.; Arzhangi, S.; Jamali, P.; Mojahedi, F.; Taghdiri, M.; Papari, E.; Soltani Banavandi, M. J.; Akbari, S.; Tonekaboni, S. H.; Dehghani, H.; Ebrahimpou, M. R.; Bader, I.; Davarnia, B.; Cohen, M.; Khodaei, H.; Albrecht, B.; Azimi, S.; Zirn, B.; Bastami, M.; Wieczorek, D.; Bahrami, G.; Keleman, K.; Vahid, L. N.; Timmermann, B.; Pourfatemi, F.; Jankhah, A.; Chen, W.; Nikuei, P.; Kalscheuer, V. M.; Oladnabi, M.; Wienker, T. F.; Ropers, H.-H.; Najmabadi, H.: Genetics of intellectual disability in consanguineous families. Molecular Psychiatry 2018 (2018)
9. 9.
   MPG.PuRe

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   Smith, Z. D.; Shi, J.; Gu, H.; Donaghey, J.; Clement, K.; Cacchiarelli, D.; Gnirke, A.; Michor, F.; Meissner, A.: Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer. Nature 549 (7673), pp. 543 - 547 (2017)
10. 10.
    MPG.PuRe

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    Choi, J.; Huebner, A. J.; Clement, K.; Walsh, R. M.; Savol, A.; Lin, K.; Gu, H.; Di Stefano, B.; Brumbaugh, J.; Kim, S.-Y. et al.; Sharif, J.; Rose, C. M.; Mohammad, A.; Odajima, J.; Charron, J.; Shioda, T.; Gnirke, A.; Gygi, S.; Koseki, H.; Sadreyev, R. I.; Xiao, A.; Meissner, A.; Hochedlinger, K.: Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells. Nature 548 (7666), pp. 219 - 223 (2017)
11. 11.
    MPG.PuRe

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    Choi, J.; Clement, K.; Huebner, A. J.; Webster, J.; Etchegaray, J.-P.; Gu, H.; Boyle, P.; Elling, U.; Mostoslavsky, R.; Sadreyev, R. et al.; Park, P. J.; Gygi, S. P.; Meissner, A.; Hochedlinger, K.: DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells. Cell Stem Cell 20 (5), pp. 706 - 719 (2017)
12. 12.
    MPG.PuRe

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    Warren, C. R.; O’Sullivan, J. F.; Friesen, M.; Becker, C. E.; Zhang, X.; Liu, P.; Wakabayashi, Y.; Morningstar, J. E.; Shi, X.; Choi, J. et al.; Xia, F.; Peters, D. T.; Florido, M. H. C.; Tsankov, A. M.; Duberow, E.; Comisar, L.; Shay, J.; Jiang, X.; Meissner, A.; Musunuro, K.; Kathiresan, S.; Daheron, L.; Zhu, J.; Gerszten, R. E.; Deo, R. C.; Vasan, R. S.; O’Donnell, C. J.; Cowan, C. A.: Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. Cell Stem Cell 20 (4), pp. 547 - 557 (2017)
13. 13.
    MPG.PuRe

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    Yu , V. W. C.; Yusuf , R. Z.; Oki , T.; Wu, J.; Saez, B.; Wang, X.; Cook , C.; Baryawno , N.; Ziller , M. J.; Lee , E. et al.; Gu, H.; Meissner, A.; Lin, C. P.; Kharchenko, P. V.; Scadden , D. T.: Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells - Correction. Cell 168 (5), pp. 944 - 945 (2017)
14. 14.
    MPG.PuRe

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    Liu , L. L.; Brumbaugh , J.; Bar-Nur , O.; Smith , Z.; Stadtfeld , M.; Meissner, A.; Hochedlinger, K.; Michor, F.: Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells. Cell Reports 17 (12), pp. 3395 - 3406 (2016)
15. 15.
    MPG.PuRe

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    Ziller, M. J.; Stamenova, E. K.; Gu, H.; Gnirke, A.; Meissner, A.: Targeted bisulfite sequencing of the dynamic DNA methylome. Epigenetics & Chromatin 9, 9:55 (2016)
16. 16.
    MPG.PuRe

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    Kottakis, F.; Nicolay, B. N.; Roumane, A.; Karnik, R.; Gu, H.; Nagle, J. M.; Boukhali, M.; Hayward, M. C.; Li, Y. Y.; Chen, T. et al.; Liesa, M.; Hammerman, P. S.; Wong, K. K.; Hayes, D. N.; Shirihai, O. S.; Dyson, N. J.; Haas, W.; Meissner, A.; Bardeesy, N.: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature 539 (7629), pp. 390 - 395 (2016)
17. 17.
    MPG.PuRe

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    Yu , V. W. C.; Yusuf , R. Z.; Oki , T.; Wu, J.; Saez, B.; Wang, X.; Cook , C.; Baryawno , N.; Ziller , M. J.; Lee , E. et al.; Gu, H.; Meissner, A.; Lin, C. P.; Kharchenko, P. V.; Scadden , D. T.: Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells. Cell 167 (5), e17, pp. 1310 - 1322 (2016)
18. 18.
    MPG.PuRe

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    Aguilar, C. A.; Pop, R.; Shcherbina, A.; Watts, A.; Matheny Jr., R. W.; Cacchiarelli, D.; Han, W. M.; Shin, E.; Nakhai, S. A.; Jang, Y. C. et al.; Carrigan, C. T.; Gifford, C. A.; Kottke, M. A.; Cesana, M.; Lee, J.; Urso, M. L.; Meissner, A.: Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma. Stem Cell Reports 7 (5), pp. 983 - 997 (2016)
19. 19.
    MPG.PuRe

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    Libertini, E.; Heath, S. C.; Hamoudi, R. A.; Gut, M.; Ziller, M. J.; Herrero, J.; Czyz, A.; Ruotti, V.; Stunnenberg, H. G.; Frontini, M. et al.; Ouwehand, W. H.; Meissner, A.: Saturation analysis for whole-genome bisulfite sequencing data. Nature Biotechnology 34 (7), pp. 691 - 693 (2016)
20. 20.
    MPG.PuRe

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    Libertini, E.; Heath, S. C.; Hamoudi, R. A.; Gut, M.; Ziller, M. J.; Czyz, A.; Ruotti, V.; Stunnenberg, H. G.; Frontini, M.; Ouwehand, W. H. et al.; Meissner, A.: Information recovery from low coverage whole-genome bisulfite sequencing. Nature Communications 2016, 7:11306 (2016)