Publications

Chteinberg, E.; Kolarova, J.; Vogt, J.; Macamo, A.; Bormann, F.; Kretzmer, H.; Speel, E. J.; van den Oord, J.; Schneider, C.; Stilgenbauer, S. et al.; Becker, J. C.; Winnepenninckx, V.; Biessen, E.; Zenke, M.; Kurz, A. K.; Siebert, R.; Zur Hausen , A.: The significance of PAX5 in Merkel cell carcinoma. The Journal of Pathology: an Official Journal of the Pathological Society of Great Britain and Ireland 266 (1), pp. 81 - 94 (2025)

Villaronga-Luque, A.; Savill, R. G.; López-Anguita, N.; Bolondi, A.; Garai, S.; Gassaloglu, S. I.; Rouatbi, R.; Schmeisser, K.; Poddar, A.; Bauer, L. et al.; Alves, T.; Traikov, S.; Rodenfels, J.; Chavakis, T.; Bulut-Karslioglu, A.; Veenvliet, J. V.: Integrated molecular-phenotypic profiling reveals metabolic control of morphological variation in a stem-cell-based embryo model. Cell Stem Cell 32 (5), pp. 759 - 777 (2025)

Glaser , S.; Fischer, A.; Martínez-Manjón, J. E.; López, C.; Kretzmer, H.; Burkhardt, B.; Hübschmann, D.; Hummel, M.; Klapper, W.; Kolarova, J. et al.; Kreuz, M.; Ott, G. e. a.: Subgrouping germinal center-derived B-cell lymphomas based on machine learning-deduced DNA methylation modules. Leukemia 39 (4), pp. 967 - 971 (2025)

Brändl, B.; Steiger, M.; Kubelt, C.; Rohrandt, C.; Zhu, Z.; Evers, M.; Wang, G.; Schuldt, B.; Afflerbach, A.-K.; Wong, D. et al.; Lum, A.; Halldorsson, S.; Djirackor, L.; Leske, H.; Magadeeva, S.; Smicius, R.; Quedenau, C.; Schmidt, N. O.; Schüller, U.; Vik-Mo, E. O.; Proescholdt, M.; Riemenschneider, M. J.; Zadeh, G.; Ammerpohl, O.; Yip, S.; Synowitz, M.; van Bömmel, A.; Kretzmer, H.; Müller, F.-J.: Rapid brain tumor classification from sparse epigenomic data. Nature Medicine 31 (3), pp. 840 - 848 (2025)

Lauer, S. M.; Gasse, J.; Krizsan, A.; Reepmeyer, M.; Sprink, T.; Nikolay, R.; Spahn, C. M. T.; Hoffmann, R.: The proline-rich antimicrobial peptide Api137 disrupts large ribosomal subunit assembly and induces misfolding. Nature Communications 16 (1), Article 567 (2025)

McIntyre, A. B. R.; Tschan, A. B.; Meyer, K.; Walser, S.; Rai, A. K.; Fujita, K.; Pelkmans, L.: Phosphorylation of a nuclear condensate regulates cohesion and mRNA retention. Nature Communications 16 (1), Article 390 (2025)

Glaser, S.; Kretzmer, H.; Kolassa, I. T.; Schlesner, M.; Fischer, A.; Fenske, I.; Siebert, R.; Ammerpohl , O.: Navigating Illumina DNA methylation data: biology versus technical artefacts. NAR: genomics and bioinformatics 6 (4), Article lqae181 (2024)

Hasenbein, T. P.; Hoelzl, S.; Smith, Z. D.; Gerhardinger, C.; Gonner, M. O. C.; Aguilar-Pimentel, A.; Amarie, O. V.; Becker, L.; Calzada-Wack, J.; Dragano, N. R. V. et al.; da Silva-Buttkus, P.; Garrett, L.; Hölter, S. M.; Kraiger, M.; Östereicher, M. A.; Rathkolb, B.; Sanz-Moreno, A.; Spielmann, N.; Wurst, W.; Gailus-Durner, V.; Fuchs, H.; Hrabě de Angelis, M.; Meissner, A.; Engelhardt, S.; Rinn, J. L.; Andergassen, D.: X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes. Nature Communications 15 (1), Article 10631 (2024)

Reissland, M.; Hartmann, O.; Tauch, S. e. a.; Diefenbacher, M. E.: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer. Oncogene 43 (50), pp. 3645 - 3659 (2024)

Iyer, D. P.; Khoei , H. H.; van der Weijden, V. A.; Kagawa, H.; Pradhan, S. J.; Novatchkova, M.; McCarthy, A.; Rayon, T.; Simon, C. S.; Dunkel, I. et al.; Wamaitha, S. E.; Elder, K.; Snell , P.; Christie, L.; Schulz, E. G.; Niakan, K. K.; Rivron, N.; Bulut-Karslioglu, A.: mTOR activity paces human blastocyst stage developmental progression. Cell 187 (23), pp. 6566 - 6583 (2024)

Evers , M.; Brändl, B.; Rohrandt, C.; Kubelt-Kwamin, C.; Müller, F.-J.; Danso, D.; Maicher , A.; Wang, G.; Friedrichsen , S.; Kolkenbrock, S.: Rapid intraoperative amplicon sequencing of CNS tumor markers. Computational and Structural Biotechnology Journal 26, pp. 51 - 57 (2024)

Stötzel, M.; Cheng, C.-Y.; Ilik, I. A.; Sampath Kumar, A.; Akbari-Omgba, P.; van der Weijden, V. A.; Zhang, Y.; Vingron, M.; Meissner, A.; Aktas, T. et al.; Kretzmer, H.; Bulut-Karslioglu, A.: TET activity safeguards pluripotency throughout embryonic dormancy. Nature Structural & Molecular Biology 31 (10), pp. 1625 - 1639 (2024)

Fleischmann, L. S.; Nemes, K.; Glaser, S.; Kouroukli, A. G.; Boros , M.; Bens, S.; Dahlum, S.; Kretzmer, H.; Oyen, F.; Gerss, J. et al.; Hasselblatt, M.; Frühwald, M. C.; Siebert, R.: Constitutional mosaicism of pathogenic variants in SMARCB1 in a subset of patients with sporadic rhabdoid tumors. Neuro-Oncology: official journal of the World Federation of Neuro-Oncology, Article noae188 (2024)

Naderi, J.; Magalhães, A. P.; Kibar, G.; Stik, G.; Zhang, Y.; Mackowiak, S.; Wieler, H. M.; Rossi, F.; Buschow, R.; Christou-Kent, M. et al.; Alcoverro-Bertran, M.; Graf, T.; Vingron, M.; Hnisz, D.: An activity-specificity trade-off encoded in human transcription factors. Nature Cell Biology 26 (8), pp. 1309 - 1321 (2024)

Roessner, P. M.; Seufert, I.; Chapaprieta, V.; Jayabalan, R.; Briesch, H.; Massoni-Badosa, R.; Boskovic, P.; Benckendorff, J. ....; Kretzmer, H.; Naake, T. e. a.: T-bet suppresses proliferation of malignant B cells in chronic lymphocytic leukemia. Blood 144 (5), pp. 510 - 524 (2024)

Batki, J.; Hetzel, S.; Schifferl, D.; Bolondi, A.; Walther, M.; Wittler, L.; Grosswendt, S.; Herrmann, B. G.; Meissner, A.: Extraembryonic gut endoderm cells undergo programmed cell death during development. Nature Cell Biology 26 (6), pp. 868 - 877 (2024)

van der Weijden, V. A.; Bulut-Karslioglu, A.: Embryos burn fat in standby. Trends in Cell Biology 34 (9), pp. 700 - 702 (2024)

Bolondi, A.; Law, B. K.; Kretzmer, H.; Gassaloglu, S. I.; Buschow, R.; Riemenschneider, C.; Yang, D.; Walther, M.; Veenvliet, J. V.; Meissner, A. et al.; Smith, Z. D.; Chan, M. M.: Reconstructing axial progenitor field dynamics in mouse stem cell-derived embryoids. Developmental Cell 59 (12), pp. 1489 - 1505 (2024)

Borisova, E.; Newman, A. G.; Couce Iglesias, M.; Dannenberg, R.; Schaub, T.; Qin, B.; Rusanova, A.; Brockmann, M.; Koch, J.; Daniels, M. et al.; Turko, P.; Jahn, O.; Kaplan, D. R.; Rosário, M.; Iwawaki, T.; Spahn, C. M. T.; Rosenmund, C.; Meierhofer, D.; Kraushar, M. L.; Tarabykin, V.; Ambrozkiewicz, M. C.: Protein translation rate determines neocortical neuron fate. Nature Communications 15 (1), Article 4879 (2024)

Sato, N. S.; Rosa , V. S.; Makhlouf, A.; Kretzmer, H.; Sampath Kumar, A.; Grosswendt, S.; Mattei, A. L.; Courbot, O.; Wolf, S.; Boulanger, J. et al.; Langevin, F.; Wiacek, M.; Karpinski, D.; Elosegui-Artola, A.; Meissner, A.; Zernicka-Goetz , M.; Shahbazi, M. N.: Basal delamination during mouse gastrulation primes pluripotent cells for differentiation. Developmental Cell 59 (10), pp. 1252 - 1268 (2024)