Publications of Lars Wittler
All genres
Journal Article (39)
21.
Journal Article
538 (7624), pp. 265 - 269 (2016)
Formation of novel chromatin domains determines pathogenicity of genomic duplications. Nature 22.
Journal Article
34 (7), pp. 1790 - 800 (2016)
Different Concentrations of FGF Ligands, FGF2 or FGF8 Determine Distinct States of WNT-Induced Presomitic Mesoderm. Stem Cells 23.
Journal Article
26 (2), pp. 183 - 191 (2016)
Exome Sequencing and CRISPR/Cas Genome Editing Identify Mutations of ZAK as a Cause of Limb Defects in Humans and Mice. Genome Research 24.
Journal Article
575 (2 Pt 2), pp. 438 - 451 (2016)
Analysis of the Fam181 gene family during mouse development reveals distinct strain-specific expression patterns, suggesting a role in nervous system development and function. Gene 25.
Journal Article
161 (5), pp. 1012 - 1025 (2015)
Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions. Cell 26.
Journal Article
10 (5), pp. 833 - 839 (2015)
Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice. Cell Reports 27.
Journal Article
23 (20), pp. 5536 - 5544 (2014)
Genome-wide association study and mouse expression data identify a highly conserved 32 kb intergenic region between WNT3 and WNT9b as possible susceptibility locus for isolated classic exstrophy of the bladder. Human Molecular Genetics 28.
Journal Article
133, pp. 23 - 35 (2014)
SRF is essential for mesodermal cell migration during elongation of the embryonic body axis. Mechanisms of Development 29.
Journal Article
100 (6), pp. 512 - 517 (2014)
Classic bladder exstrophy: Frequent 22q11.21 duplications and definition of a 414 kb phenocritical region. Birth Defects Research Part A: Clinical and Molecular Teratology 30.
Journal Article
141 (11), pp. 2325 - 2330 (2014)
The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo. Development 31.
Journal Article
343 (6176), pp. 1264 - 1266 (2014)
Dlk1 promotes a fast motor neuron biophysical signature required for peak force execution. Science 32.
Journal Article
21 (12), pp. 1377 - 1382 (2013)
De novo microduplications at 1q41, 2q37.3, and 8q24.3 in patients with VATER/VACTERL association. European journal of human genetics: EJHG ; the official journal of the European Society of Human Genetics 33.
Journal Article
24 (2), pp. 206 - 214 (2013)
The tissue-specific IncRNA Fendrr is an essential regulator of heart and body wall development in the mouse. Developmental Cell 34.
Journal Article
372 (1), pp. 55 - 67 (2012)
In vivo knockdown of Brachyury results in skeletal defects and urorectal malformations resembling caudal regression syndrome. Developmental Biology 35.
Journal Article
91 (4), pp. 629 - 635 (2012)
Homeotic arm-to-leg transformation associated with genomic rearrangements at the PITX1 locus. American Journal of Human Genetics 36.
Journal Article
506 (2), pp. 392 - 395 (2012)
Murine expression and mutation analyses of the prostate androgen-regulated mucin-like protein 1 (Parm1) gene, a candidate for human epispadias. Gene 37.
Journal Article
27 (6), pp. 755 - 65 (2011)
Genome-wide expression profiling of urinary bladder implicates desmosomal and cytoskeletal dysregulation in the bladder exstrophy-epispadias complex. International Journal of Molecular Medicine 38.
Journal Article
38 (11), p. e122 - e122 (2010)
An inducible RNA interference system for the functional dissection of mouse embryogenesis. Nucleic Acids Research 39.
Journal Article
8 (8), pp. 784 - 789 (2007)
Expression of Msgn1 in the presomitic mesoderm is controlled by synergism of WNT signalling and Tbx6. EMBO Reports Other (1)
40.
Other
Functional dissection of TADs reveals non-essential and instructive roles in regulating gene expression, bioRxiv (Preprint Server) 2019, (2019)