Publications of Michal R. Schweiger

Hussong, M.; Kaehler, C.; Kerick, M.; Grimm, C.; Franz, A.; Timmermann, B.; Welzel, F.; Isensee, J.; Hucho, T.; Krobitsch, S. et al.; Schweiger, M. R.: The bromodomain protein BRD4 regulates splicing during heat shock. Nucleic Acids Research (London) 45 (1), pp. 382 - 394 (2017)

Castelo-Branco, P.; Leão, R.; Lipman, T.; Campbell, B.; Lee, D.; Price, A.; Zhang, C.; Heidari, A.; Stephens, D.; Boerno, S. T. et al.; Coelho, H.; Gomes, A.; Domingos, C.; Apolonio, J. D.; Schäfer, G.; Bristow, R. G.; Schweiger, M. R.; Hamilton, R.; Zlotta, A.; Figueiredo, A.; Helmut, K.; Sültmann, H.; Tabori, U.: A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: A retrospective cohort study. Oncotarget 36 (7), pp. 57726 - 57736 (2016)

Pasqualini, L.; Bu, H.; Puhr, M.; Narisu, N.; Rainer, J.; Schlick, B.; Schäfer, G.; Angelova, M.; Trajanoski, Z.; Börno, S. T. et al.; Schweiger, M. R.; Fuchsberger, C.; Klocker, H.: miR-22 and miR-29a are members of the androgen receptor cistrome modulating LAMC1 and Mcl-1 in prostate cancer. Molecular Endocrinology 29 (7), pp. 1037 - 1054 (2015)

Zemojtel, T.; Köhler, S.; Mackenroth, L.; Jäger, M.; Hecht, J.; Krawitz, P.; Graul-Neumann, L.; Doelken, S.; Ehmke, N.; Spielmann, M. et al.; Oien, N. C.; Schweiger, M. R.; Krüger, U.; Frommer, G.; Fischer, B.; Kornak, U.; Flöttmann, R.; Ardeshirdavani, A.; Moreau, Y.; Lewis, S. E.; Haendel, M.; Smedley, D.; Horn, D.; Mundlos, S.; Robinson, P. N.: Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome. Science Translational Madicine 6 (252), 252ra123 (2014)

Hussong, M.; Börno, S.; Kerick, M.; Wunderlich, A.; Franz, A.; Sültmann, H.; Timmermann, B.; Lehrach, H.; Hirsch-Kauffmann, M.; Schweiger, M. R.: The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. Cell Death and Disease 5, 5:e1195 (2014)

Hussong, M.; Börno, S. T.; Kerick, M.; Wunderlich, A.; Franz, A.; Sültmann, H.; Timmermann, B.; Lehrach, H.; Hirsch-Kauffmann, M.; Schweiger, M. R.: The bromodomain protein BRD4 regulates the KEAP1/NRF2 dependent oxidative stress response. Cell Death and Disease 2014 (5), e1195 (2014)

Röhr, C.; Kerick, M.; Fischer, A.; Kuehn, A.; Kashofer, K.; Timmermann, B.; Daskalaki, A.; Meinel, T.; Drichel, D.; Börno, S. et al.; Nowka, A.; Krobitsch, S.; McHardy, A. C.; Kratsch, C.; Becker, T.; Wunderlich, A.; Barmeyer, C.; Viertler, C.; Zatloukal, K.; Wierling, C.; Lehrach, H.; Schweiger, M.-R.: High-Throughput miRNA and mRNA Sequencing of Paired Colorectal Normal, Tumor and Metastasis Tissues and Bioinformatic Modeling of miRNA-1 Therapeutic Applications. PLoS One 8 (7), p. e67461 - e67461 (2013)

Kacprzyk, L. A.; Laible, M.; Andrasiuk, T.; Brase, J. C.; Börno, S.; Falth, M.; Kuner, R.; Lehrach, H.; Schweiger, M. R.; Sultmann, H.: ERG Induces Epigenetic Activation of Tudor Domain-Containing Protein 1 (TDRD1) in ERG Rearrangement-Positive Prostate Cancer. PLoS One 8 (3), p. e59976 - e59976 (2013)

Bu, H.; Schweiger, M. R.; Manke, T.; Wunderlich, A.; Timmermann, B.; Kerick, M.; Pasqualini, L.; Shehu, E.; Fuchsberger, C.; Cato, A. C. et al.; Klocker, H.: Anterior gradient 2 and 3--two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells. FEBS Journal 280 (5), pp. 1249 - 66 (2013)

Grimm, C.; Chavez, L.; Vilardell, M.; Farrall, A.; Tierling, S.; Böhm, J. W.; Grote, P.; Lienhard, M.; Dietrich, J.; Timmermann, B. et al.; Walter, J.; Schweiger, M. R.; Lehrach, H.; Herwig, R.; Herrmann, B. G.; Morkel, M.: DNA–Methylome Analysis of Mouse Intestinal Adenoma Identifies a Tumour-Specific Signature That Is Partly Conserved in Human Colon Cancer. PLoS Genetics 9 (2), p. e1003250 - e1003250 (2013)

Schweiger, M. R.; Barmeyer, C.; Timmermann, B.: Genomics and epigenomics: new promises of personalized medicine for cancer patients. Briefings in Functional Genomics 12 (5), pp. 411 - 21 (2013)

Schweiger, M.-R.; Hussong, M.; Roehr, C.; Lehrach, H.: Genomics and epigenomics of colorectal cancer. Wiley Interdisciplinary Reviews: Cognitive Science 5 (2), pp. 205 - 219 (2013)

Börno, S.; Fischer, A.; Kerick, M.; Falth, M.; Laible, M.; Brase, J. C.; Kuner, R.; Dahl, A.; Grimm, C.; Sayanjali, B. et al.; Isau, M.; Röhr, C.; Wunderlich, A.; Timmermann, B.; Claus, R.; Plass, C.; Graefen, M.; Simon, R.; Demichelis, F.; Rubin, M. A.; Sauter, G.; Schlomm, T.; Sültmann, H.; Lehrach, H.; Schweiger, M. R.: Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation. Cancer Discovery 2 (11), pp. 1024 - 1035 (2012)

Querfurth, R.; Fischer, A.; Schweiger, M. R.; Lehrach, H.; Mertes, F.: Creation and application of immortalized bait libraries for targeted enrichment and next-generation sequencing. Biotechniques 52 (6), pp. 375 - 380 (2012)

Meinel, T.; Schweiger, M. R.; Ludewig, A. H.; Chenna, R.; Krobitsch, S.; Herwig, R.: Ortho2ExpressMatrix--a web server that interprets cross-species gene expression data by gene family information. BMC Genomics 12, 12:483 (2011)

Hallen, L.; Klein, H.; Stoschek, C.; Wehrmeyer, S.; Nonhoff, U.; Ralser, M.; Wilde, J.; Rohr, C.; Schweiger, M. R.; Zatloukal, K. et al.; Vingron, M.; Lehrach, H.; Konthur, Z.; Krobitsch, S.: The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2. Human Molecular Genetics 20, pp. 104 - 114 (2011)

Kerick, M.; Isau, M.; Timmermann, B.; Sultmann, H.; Herwig, R.; Krobitsch, S.; Schaefer, G.; Verdorfer, I.; Bartsch, G.; Klocker, H. et al.; Lehrach, H.; Schweiger, M. R.: Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity. BMC Med Genomics 4, p. 68 (2011)

Kohlmann, A.; Klein, H. U.; Weissmann, S.; Bresolin, S.; Chaplin, T.; Cuppens, H.; Haschke-Becher, E.; Garicochea, B.; Grossmann, V.; Hanczaruk, B. et al.; Hebestreit, K.; Gabriel, C.; Iacobucci, I.; Jansen, J. H.; te Kronnie, G.; van de Locht, L.; Martinelli, G.; McGowan, K.; Schweiger, M. R.; Timmermann, B.; Vandenberghe, P.; Young, B. D.; Dugas, M.; Haferlach, T.: The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories. Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K 25 (12), pp. 1840 - 8 (2011)

Kruger, A.; Gruning, N. M.; Wamelink, M. M.; Kerick, M.; Kirpy, A.; Parkhomchuk, D.; Bluemlein, K.; Schweiger, M. R.; Soldatov, A.; Lehrach, H. et al.; Jakobs, C.; Ralser, M.: The pentose phosphate pathway is a metabolic redox sensor and regulates transcription during the antioxidant response. Antioxidants & Redox Signaling 15 (2), pp. 311 - 24 (2011)

Rodelsperger, C.; Krawitz, P.; Bauer, S.; Hecht, J.; Bigham, A. W.; Bamshad, M.; de Condor, B. J.; Schweiger, M. R.; Robinson, P. N.: Identity-by-descent filtering of exome sequence data for disease-gene identification in autosomal recessive disorders. Bioinformatics 27 (6), pp. 829 - 36 (2011)