Publications of Bernd Timmermann

Mertes, F.; Lichtner, B.; Kuhl, H.; Blattner , M.; Otte, J.; Wruck, W.; Timmermann, B.; Lehrach, H.; Adjaye, J.: Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells. BMC Genomics 16, 16:925 (2015)

Satzger, I.; Marks, L.; Kerick, M.; Klages, S.; Berking, C.; Herbst, R.; Völker, B.; Schacht, V.; Timmermann, B.; Gutzmer, R.: Allele frequencies of BRAFV600 mutations in primary melanomas and matched metastases and their relevance for BRAF inhibitor therapy in metastatic melanoma. Oncotarget 2015, 5634 (2015)

Sudmant, P. H.; Rausch, T.; Gardner, E. J.; Handsaker, R. E.; Abyzov, A.; Huddleston, J.; The 1000 Genomes Project Consortium; Timmermann, B.; Herwig, R.; Lehrach, H.: An integrated map of structural variation in 2,504 human genomes. Nature 526 (7571), pp. 75 - 81 (2015)

The 1000 Genome Project Consortium; Lehrach, H.; Amstislavskiy, V.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M.-L.; Herwig, R.: A global reference for human genetic variation. Nature 526 (7571), pp. 68 - 74 (2015)

Bernal Ulloa, S. M.; Heinzmann, J.; Herrmann, D.; Timmermann, B.; Baulain, U.; Großfeld, R.; Diederich, M.; Lucas-Hahn, A.; Niemann, H.: Effects of different oocyte retrieval and in vitro maturation systems on bovine embryo development and quality. Zygote 23 (3), pp. 367 - 377 (2015)

Lupiáñez, D. G.; Kraft, K.; Heinrich, V.; Krawitz, P.; Brancati, F.; Klopocki, E.; Horn, D.; Kayserili, H.; Opitz, J. M.; Laxova, R. et al.; Santos-Simarro, F.; Gilbert-Dussardier, B.; Wittler, L.; Borschiwer, M.; Haas, S. A.; Osterwalder, M.; Franke, M.; Timmermann, B.; Hecht, J.; Spielmann, M.; Visel, A.; Mundlos, S.: Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions. Cell 161 (5), pp. 1012 - 1025 (2015)

Seifert, R.; Flick, M.; Bönigk, W.; Alvarez, L.; Trötschel, C.; Poetsch, A.; Müller, A.; Goodwin, N.; Pelzer, P.; Kashikar, N. D. et al.; Kremmer, E.; Jikeli, J.; Timmermann, B.; Kuhl, H.; Fridman, D.; Windler, F.; Kaupp, U. B.; Strünker, T.: The CatSper channel controls chemosensation in sea urchin sperm. EMBO Journal 34 (3), pp. 379 - 392 (2015)

Frankl-Vilches, C.; Kuhl, H.; Werber, M.; Klages, S.; Kerick, M.; Bakker, A.; de Oliveira, E. H. C.; Reusch, C.; Capuano, F.; Vowinckel, J. et al.; Leitner, S.; Ralser, M.; Timmermann, B.; Gahr, M.: Using the canary genome to decipher the evolution of hormone-sensitive gene regulation in seasonal singing birds. Genome Biology: Biology for the Post-Genomic Era 16 (1), 16:19 (2015)

Willems, T.; Gymrek, M.; Highnam, G.; The 1000 Genomes Project, C.; Herwig, R.; Lehrach, H.; Sudbrak, R.; Timmermann, B.; Mittelman, D.; Erlich, Y.: The landscape of human STR variation. Genome Research 24 (11), pp. 1894 - 1904 (2014)

Krawitz, P. M.; Schiska, D.; Krüger, U.; Appelt, S.; Heinrich, V.; Parkhomchuk, D.; Timmermann, B.; Millan, J. M.; Robinson, P. N.; Mundlos, S. et al.; Hecht, J.; Gross, M.: Screening for single nucleotide variants, small indels and exon deletions with a next-generation sequencing based gene panel approach for Usher syndrome. Molecular Genetics and Genomic Medicine 2 (5), pp. 393 - 401 (2014)

Colonna, V.; Ayub, Q.; Chen, Y.; Pagani, L.; Luisi, P.; Pybus, M.; Garrison, E.; Xue, Y.; Tyler-Smith, C.; 1000 Genomes Project, C. et al.; Sudbrak, R.; Albrecht, M.; Amstislavskiy, V.; Borodina, T. A.; Dahl, A.; Davydov, A.; Herwig, R.; Marquardt, P.; Mertes, F.; Nietfeld, W.; Parkhomchuk, D.; Soldatov, A. V.; Timmermann, B.; Tolzmann, M.; Lehrach, H.; Yaspo, M. L.: Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences. Genome Biology: Biology for the Post-Genomic Era 15 (6), R88 (2014)

Grunert, M.; Dorn, C.; Schueler, M.; Dunkel, I.; Schlesinger, J.; Mebus, S.; Alexi-Meskishvili, V.; Perrot, A.; Wassilew, K.; Timmermann, B. et al.; Hetzer, R.; Berger, F.; Sperling, S. R.: Rare and Private Variations in Neural Crest, Apoptosis and Sarcomere Genes Define the Polygenic Background of Isolated Tetralogy of Fallot. Human Molecular Genetics 23 (12), pp. 3115 - 3128 (2014)

Delaneau, O.; Marchini, J.; 1000 Genomes Project, C.; Lehrach, H.; Sudbrak, R.; Amstislavskiy, V. S.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B. et al.; Yaspo, M. L.; Herwig, R.: Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel. Nature Communications 5, 5:3934 (2014)

Draaken, M.; Baudisch, F.; Timmermann, B.; Kuhl, H.; Kerick, M.; Proske, J.; Wittler, L.; Pennimpede, T.; Ebert, A. K.; Rösch, W. et al.; Stein, R.; Bartels, E.; von Lowtzow, C.; Boemers, T. M.; Herms, S.; Gearhart, J. P.; Lakshmanan, Y.; Kockum, C. C.; Holmdahl, G.; Läckgren, G.; Nordenskjöld, A.; Boyadjiev, S. A.; Herrmann, B. G.; Nöthen, M. M.; Ludwig, M.; Reutter, H.: Classic bladder exstrophy: Frequent 22q11.21 duplications and definition of a 414 kb phenocritical region. Birth Defects Research Part A: Clinical and Molecular Teratology 100 (6), pp. 512 - 517 (2014)

Werber, M.; Wittler, L.; Timmermann, B.; Grote, P.; Herrmann, B. G.: The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo. Development 141 (11), pp. 2325 - 2330 (2014)

Hussong, M.; Börno, S.; Kerick, M.; Wunderlich, A.; Franz, A.; Sültmann, H.; Timmermann, B.; Lehrach, H.; Hirsch-Kauffmann, M.; Schweiger, M. R.: The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. Cell Death and Disease 5, 5:e1195 (2014)

Hussong, M.; Börno, S. T.; Kerick, M.; Wunderlich, A.; Franz, A.; Sültmann, H.; Timmermann, B.; Lehrach, H.; Hirsch-Kauffmann, M.; Schweiger, M. R.: The bromodomain protein BRD4 regulates the KEAP1/NRF2 dependent oxidative stress response. Cell Death and Disease 2014 (5), e1195 (2014)

Abyzov, A.; Iskow, R.; Gokcumen, O.; Radke, D. W.; Balasubramanian, S.; Pei, B.; Habegger, L.; 1000 Genomes Project, C.; Timmermann, B.; Lee, C. et al.; Gerstein, M.: Analysis of variable retroduplications in human populations suggests coupling of retrotransposition to cell division. Genome Research 23 (12), pp. 2042 - 2052 (2013)

Ibrahim, D.; Hansen, P.; Rödelsperger, C.; Stiege, A. C.; Doelken, S. C.; Horn, D.; Jäger, M.; Janetzki, C.; Krawitz, P.; Leschik, G. et al.; Wagner, F.; Scheuer, T.; Schmidt-von Kegler, M.; Seemann, P.; Timmermann, B.; Robinson, P. N.; Mundlos, S.; Hecht, J.: Distinct global shifts in genomic binding profiles of limb malformation associated HOXD13 mutations. Genome Research 23 (12), pp. 2091 - 2102 (2013)

Khurana, E.; Fu, Y.; Colonna, V.; Mu, X. J.; Kang, H. M.; Lappalainen, T.; Sboner, A.; Lochovsky, L.; Chen, J.; Harmanci, A. et al.; Das, J.; Abyzov, A.; Balasubramanian, S.; Beal, K.; Chakravarty, D.; Challis, D.; Chen, Y.; Clarke, D.; Clarke, L.; Cunningham, F.; Evani, U. S.; Flicek, P.; Fragoza, R.; Garrison, E.; Gibbs, R.; Gumus, Z. H.; Herrero, J.; Kitabayashi, N.; Kong, Y.; Lage, K.; Liluashvili, V.; Lipkin, S. M.; MacArthur, D. G.; Marth, G.; Muzny, D.; Pers, T. H.; Ritchie, G. R.; Rosenfeld, J. A.; Sisu, C.; Wei, X.; Wilson, M.; Xue, Y.; Yu, F.; 1000 Genomes Project, C.; Lehrach, H.; Sudbrak, R.; Albrecht, M. W.; Amstislavskiy, V.; Borodina, T. A.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M. L.; Dermitzakis, E. T.; Yu, H.; Rubin, M. A.; Tyler-Smith, C.; Gerstein, M.: Integrative annotation of variants from 1092 humans: application to cancer genomics. Science 342 (6154), p. 1235587 - 1235587 (2013)