Suchergebnisse

Wruck, W.; Kashofer, K.; Rehman, S.; Daskalaki, A.; Berg, D.; Gralka, E.; Jozefczuk, J.; Drews, K.; Pandey, V.; Regenbrecht, C. et al.; Wierling, C. K.; Turano, P.; Korf, U.; Zatloukal, K.; Lehrach, H.; Westerhoff, H. V.; Adjaye, J.: Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes. Scientific Data 2, 150068 (2015)

Kärst, S.; Arends, D.; Heise, S.; Trost, J.; Yaspo-Lehrach, M.-L.; Amstislavskiy, V.; Risch, T.; Lehrach, H.; Brockmann, G.: Erratum. BMC Genomics 16, S. 1018 - 1018 (2015)

Mertes, F.; Lichtner, B.; Kuhl, H.; Blattner , M.; Otte, J.; Wruck, W.; Timmermann, B.; Lehrach, H.; Adjaye, J.: Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells. BMC Genomics 16, 16:925 (2015)

Kärst, S.; Arends, D.; Heise, S.; Trost, J.; Yaspo-Lehrach, M.-L.; Amstislavskiy, V.; Risch, T.; Lehrach, H.: The direction of cross affects [corrected] obesity after puberty in male but not female offspring. BMC Genomics 16, S. 904 (2015)

Lehrach, H.: Virtual Clinical Trials, an Essential Step in Increasing the Effectiveness of the Drug Development Process. Public Health Genomics 18 (6), S. 366 - 371 (2015)

Sudmant, P. H.; Rausch, T.; Gardner, E. J.; Handsaker, R. E.; Abyzov, A.; Huddleston, J.; The 1000 Genomes Project Consortium; Timmermann, B.; Herwig, R.; Lehrach, H.: An integrated map of structural variation in 2,504 human genomes. Nature 526 (7571), S. 75 - 81 (2015)

The 1000 Genome Project Consortium; Lehrach, H.; Amstislavskiy, V.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M.-L.; Herwig, R.: A global reference for human genetic variation. Nature 526 (7571), S. 68 - 74 (2015)

Fischer, U.; Forster, M.; Rinaldi, A.; Risch, T.; Sungalee, S.; Warnatz, H. J.; Bornhauser, B.; Gombert, M.; Kratsch, C.; Stutz, A. M. et al.; Sultan, M.; Tchinda, J.; Worth, C. L.; Amstislavskiy, V.; Badarinarayan, N.; Baruchel, A.; Bartram, T.; Basso, G.; Canpolat, C.; Cario, G.; Cave, H.; Dakaj, D.; Delorenzi, M.; Dobay, M. P.; Eckert, C.; Ellinghaus, E.; Eugster, S.; Frismantas, V.; Ginzel, S.; Haas, O. A.; Heidenreich, O.; Hemmrich-Stanisak, G.; Hezaveh, K.; Holl, J. I.; Hornhardt, S.; Husemann, P.; Kachroo, P.; Kratz, C. P.; Kronnie, G. T.; Marovca, B.; Niggli, F.; McHardy, A. C.; Moorman, A. V.; Panzer-Grumayer, R.; Petersen, B. S.; Raeder, B.; Ralser, M.; Rosenstiel, P.; Schäfer, D.; Schrappe, M.; Schreiber, S.; Schutte, M.; Stade, B.; Thiele, R.; Weid, N.; Vora, A.; Zaliova, M.; Zhang, L.; Zichner, T.; Zimmermann, M.; Lehrach, H.; Borkhardt, A.; Bourquin, J. P.; Franke, A.; Korbel, J. O.; Stanulla, M.; Yaspo, M. L.: Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. Nature Genetics 47 (9), S. 1020 - 1029 (2015)

Wierling, C. K.; Kessler, T.; Ogilvie, L. A.; Lange, B.; Yaspo, M.-L.; Lehrach, H.: Network and systems biology: essential steps in virtualising drug discovery and development. Drug Discovery Today: Technology 15, S. 33 - 40 (2015)

Redmer, T.; Welte, Y.; Behrens, D.; Fichtner, I.; Przybilla, D.; Wruck, W.; Yaspo, M. L.; Lehrach, H.; Schäfer, R.; Regenbrecht, C. R.: The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells. PLoS One 9 (5), e92596 (2015)

Kärst, S.; Arends, D.; Heise, S.; Trost, J.; Yaspo, M. L.; Amstislavskiy, V.; Risch, T.; Lehrach, H.; Brockmann, G. A.: Erratum to: 'The direction of cross affects obesity after puberty in male but not female offspring'. BMC Genomics 16 (1), 16:1018 (2015)

Hoehe, M. R.; Church, G. M.; Lehrach, H.; Kroslak, T.; Palczewski, S.; Nowick, K.; Schulz, S.; Suk, E.-K.; Huebsch, T.: Multiple haplotype-resolved genomes reveal population patterns of gene and protein diplotypes. Nature Communications 5, 5:5569 (2014)

Willems, T.; Gymrek, M.; Highnam, G.; The 1000 Genomes Project, C.; Herwig, R.; Lehrach, H.; Sudbrak, R.; Timmermann, B.; Mittelman, D.; Erlich, Y.: The landscape of human STR variation. Genome Research 24 (11), S. 1894 - 1904 (2014)

Pandey, V.; Sultan, M.; Kashofer, K.; Ralser, M.; Amstislavskiy, V.; Starmann, J.; Osprian, I.; Grimm, C.; Hache, H.; Yaspo, M. L. et al.; Sultmann, H.; Trauner, M.; Denk, H.; Zatloukal, K.; Lehrach, H.; Wierling, C.: Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains. PLoS One 9 (10), e111006 (2014)

Henderson, D.; Ogilvie, L. A.; Hoyle, N.; Keilholz, U.; Lange, B.; Lehrach, H.; OncoTrack, C.; Yaspo, M. L.: Personalized medicine approaches for colon cancer driven by genomics and systems biology: OncoTrack. Biotechnology Journal 9 (9), S. 1104 - 1114 (2014)

Sultan, M.; Amstislavskiy, V.; Risch, T.; Schütte, M.; Dökel, S.; Ralser, M.; Balzereit, D.; Lehrach, H.; Yaspo, M. L.: Influence of RNA extraction methods and library selection schemes on RNA-seq data. BMC Genomics 15, 15:675 (2014)

Rasche, A.; Lienhard, M.; Yaspo, M.-L.; Lehrach, H.; Herwig, R.: ARH-seq: identification of differential splicing in RNA-seq data. Nucleic Acids Research (London) 42 (14), e110 (2014)

Rykalina, V.; Shadrin, A.; Amstislavskiy, V.; Rogaev, E. I.; Lehrach, H.; Borodina, T. A.: Exome sequencing from nanogram amounts of starting DNA: comparing three approaches. PLoS One 9 (7), e101154 (2014)

Colonna, V.; Ayub, Q.; Chen, Y.; Pagani, L.; Luisi, P.; Pybus, M.; Garrison, E.; Xue, Y.; Tyler-Smith, C.; 1000 Genomes Project, C. et al.; Sudbrak, R.; Albrecht, M.; Amstislavskiy, V.; Borodina, T. A.; Dahl, A.; Davydov, A.; Herwig, R.; Marquardt, P.; Mertes, F.; Nietfeld, W.; Parkhomchuk, D.; Soldatov, A. V.; Timmermann, B.; Tolzmann, M.; Lehrach, H.; Yaspo, M. L.: Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences. Genome Biology: Biology for the Post-Genomic Era 15 (6), R88 (2014)

Hovestadt, V.; Jones, D. T.; Picelli, S.; Wang, W.; Kool, M.; Northcott, P. A.; Sultan, M.; Stachurski, K.; Ryzhova, M.; Warnatz, H.-J. et al.; Ralser, M.; Brun, S.; Bunt, J.; Jager, N.; Kleinheinz, K.; Erkek, S.; Weber, U. D.; Bartholomae, C. C.; von Kalle, C.; Lawerenz, C.; Eils, J.; Koster, J.; Versteeg, R.; Milde, T.; Witt, O.; Schmidt, S.; Wolf, S.; Pietsch, T.; Rutkowski, S.; Scheurlen, W.; Taylor, M. D.; Brors, B.; Felsberg, J.; Reifenberger, G.; Borkhardt, A.; Lehrach, H.; Wechsler-Reya, R. J.; Eils, R.; Yaspo, M. L.; Landgraf, P.; Korshunov, A.; Zapatka, M.; Radlwimmer, B.; Pfister, S. M.; Lichter, P.: Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing. Nature 510 (7506), S. 537 - 541 (2014)