Publications of Jörg Bürger

Qin, B.; Lauer, S. M.; Balke, A.; Vieira-Vieira, C. H.; Bürger, J.; Mielke, T.; Selbach, M.; Scheerer, P.; Spahn, C. M. T.; Nikolay, R.: Cryo-EM captures early ribosome assembly in action. Nature Communications 14 (1), Article 898 (2023)

Le-Trilling, V. T. K.; Banchenko, S.; Paydar, D.; Leipe, P. M.; Binting, L.; Lauer, S.; Graziadei, A.; Klingen, R.; Gotthold, C.; Bürger, J. et al.; Bracht, T.; Sitek, B.; Lebbink, R. J.; Malyshkina, A.; Mielke, T.; Rappsilber, J.; Spahn, C. M. T.; Voigt, S.; Trilling, M.; Schwefel, D.: Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor. EMBO Journal 42 (5), e112351 (2023)

Smirnova, J.; Loerke, J.; Kleinau, G.; Schmidt, A.; Bürger, J.; Meyer, E. H.; Mielke, T.; Scheerer, P.; Bock, R.; Spahn, C. M. T. et al.; Zoschke, R.: Structure of the actively translating plant 80S ribosome at 2.2 Å resolution. Nature Plants 9 (6), pp. 987 - 1000 (2023)

Hilal, T.; Killam, B. Y.; Grozdanović, M.; Dobosz-Bartoszek, M.; Loerke, J.; Bürger, J.; Mielke, T.; Copeland, P. R.; Simonović, M.; Spahn, C. M. T.: Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Science 376, pp. 1338 - 1343 (2022)

Heyder, N. A.; Kleinau, G.; Speck, D.; Schmidt, A.; Paisdzior, S.; Szczepek, M.; Bauer, B.; Koch, A.; Gallandi, M.; Kwiatkowski, D. et al.; Bürger, J.; Mielke, T.; Beck-Sickinger, A. G.; Hildebrand, P. W.; Spahn, C. M. T.; Hilger, D.; Schacherl, M.; Biebermann, H.; Hilal, T.; Kühnen, P.; Kobilka, B. K.; Scheerer, P.: Structures of active melanocortin-4 receptor−Gs-protein complexes with NDP-α-MSH and setmelanotide. Cell Research 31 (11), pp. 1176 - 1189 (2021)

Banchenko, S.; Krupp, F.; Gotthold, C.; Bürger, J.; Graziadei, A.; O'Reilly, F. J.; Sinn, L.; Ruda, O.; Rappsilber, J.; Spahn , C. M. T. et al.; Mielke, T.; Taylor, I. A. ..; Schwefel, D.: Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses. PLoS Pathogens 17 (8), e1009775 (2021)

Nikolay, R.; Hilal, T.; Schmidt, S.; Qin, B.; Schwefel, D.; Vieira-Vieira, C. H.; Mielke, T.; Bürger, J.: Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Molecular Cell 81 (6), pp. 1200 - 1215 (2021)

Kraushar, M. L.; Krupp, F.; Harnett, D.; Turko, P.; Ambrozkiewicz, M. C.; Sprink, T.; Imami, K.; Günnigmann, M.; Zinnall, U.; Vieira-Vieira, C. H. et al.; Schaub, T.; Münster-Wandowski, A.; Bürger, J.; Borisova, E.; Yamamot, H.; Rasin, M.-R.; Ohlen, U.; Beule, D.; Mielke, T.; Tarabykin, V.; Landthaler, M.; Kramer, G.; Vida, I.; Selbach, M.; Spahn, C. M. T.: Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit. Molecular Cell 81 (2), pp. 304 - 322 (2021)

Said, N.; Hilal, T.; Sunday, N. D.; Khatri, A.; Bürger, J.; Mielke, T.; Belogurov, G. A.; Loll, B.; Sen, R.; Artsimovitch, I. et al.; Wahl, M. C.: Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase ρ. Science 371 (6524), eabd1673 (2021)

Radon, C.; Mittelstädt, G.; Duffus, B. R.; Bürger, J.; Hartmann, T.; Mielke, T.; Teutloff, C.; Leimkühler, S.; Wendler, P.: Cryo-EM structures reveal intricate Fe-S cluster arrangement and charging in Rhodobacter capsulatus formate dehydrogenase. Nature Communications 11, 1912 (2020)

Ignatiou, A.; Brasilès, S.; El Sadek Fadel, M.; Bürger, J.; Mielke, T.; Topf, M.; Tavares, P.; Orlova, E. V.: Structural transitions during the scaffolding-driven assembly of a viral capsid. Nature Communications 2019 (10), 10:4840 | (2019)

Krupp, F.; Said, N.; Huang, Y.-H.; Loll, B.; Bürger, J.; Mielke, T.; Spahn, C. M.T.; Wahl, M. C.: Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor. Molecular Cell 74 (1), pp. 143 - 157 (2019)

Flis, J.; Holm, M.; Rundlet, E. J.; Loerke, J.; Hilal, T.; Dabrowski, M.; Bürger, J.; Mielke, T.; Blanchard, S. C.; Spahn, C. M.T. et al.; Budkevich, T. V.: tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis. Cell Reports 25 (10), e7, pp. 2676 - 2688 (2018)

Qureshi, B. M.; Behrmann, E.; Schöneberg, J.; Loerke, J.; Bürger, J.; Mielke, T.; Giesebrecht, J.; Noé, F.; Lamb, T. D.; Hofmann, K. P. et al.; Spahn, C. M. T.; Heck, M.: It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods. Open Biology 8 (8), 180075 (2018)

Nikolay, R.; Hilal, T.; Qin, B.; Mielke, T.; Bürger, J.; Loerke, J.; Textoris-Taube, K.; Nierhaus, K. H.; Spahn, C. M.T.: Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution. Molecular Cell 70 (5), e3, pp. 881 - 893 (2018)

Reddy Devullapally, P.; Bürger, J.; Mielke, T.; Konthur, Z.; Lehrach, H.; Yaspo, M.-L.; Glökler, J.; Warnatz, H.-J.: Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes. Genome Medicine 10, 10:34 (2018)

Qureshi, B. M.; Schmidt, A.; Behrmann, E.; Bürger, J.; Mielke, T.; Spahn, C. M. T.; Heck, M.; Scheerer, P.: Mechanistic insights into the role of prenyl-binding protein PrBP/δ in membrane dissociation of phosphodiesterase 6. Nature Communications 9 (1), 90 (2018)

Said, N.; Krupp, F.; Anedchenko, E.; Santos, K. F.; Dybkov, O.; Huang, Y. H.; Lee, C. T.; Loll, B.; Behrmann, E.; Buerger, J. et al.; Mielke, T.; Loerke, J.; Urlaub, H.; Spahn, C. M. T.; Weber, G.; Wahl, M. C.: Structural basis for λN-dependent processive transcription antitermination. Nature Microbiology 2, 2:17062 (2017)

Hilal, T.; Yamamoto, H.; Loerke, J.; Bürger, J.; Mielke, T.; Spahn, C. M. T.: Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution. Nature Communications 7, 7:13521 (2016)

Sprink, T.; Ramrath, D. J. F.; Yamamoto, H.; Yamamoto, K.; Loerke, J.; Ismer, J.; Hildebrand, P. W.; Scheerer, P.; Bürger, J.; Mielke, T. et al.; Spahn, C. M. T.: Structures of ribosome-bound initiation factor 2 reveal mechanism of subunit association. Science Advances 2 (3), e1501502 (2016)