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Zeitschriftenartikel (34)
1.
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Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator. Nature (2021)
2.
Zeitschriftenartikel
118 (2), e2014481118 (2021)
A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions. Proceedings of the National Academy of Sciences of the United States of America 3.
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370 (6522), eaba4937 (2020)
Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites. Science 4.
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370 (6513), S. 208 - 214 (2020)
The mole genome reveals regulatory rearrangements associated with adaptive intersexuality. Science 5.
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584, S. 102 - 108 (2020)
Epigenetic regulator function through mouse gastrulation. Nature 6.
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51 (8), S. 1263 - 1271 (2019)
Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture. Nature Genetics 7.
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2019, 528877 (2019)
Preformed Chromatin Topology Assists Transcriptional Robustness of Shh during Limb Development. bioRxiv (Preprint Server) 8.
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21 (3), S. 305 - 310 (2019)
Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations. Nature Cell Biology 9.
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50 (10), S. 1463 - 1473 (2018)
Dynamic 3D chromatin architecture determines enhancer specificity and morphogenetic identity in limb development. Nature Genetics 10.
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20 (6), S. 599 - 607 (2018)
Noncoding copy-number variations are associated with congenital limb malformation. GENETICS IN MEDICINE 11.
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50 (5), S. 662 - 667 (2018)
Polymer physics predicts the effects of structural variants on chromatin architecture. Nature Genetics 12.
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19 (1), S. 118 - 134 (2018)
BRACHYURY directs histone acetylation to target loci during mesoderm development. EMBO Reports 13.
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49 (10), S. 1539 - 1545 (2017)
Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog). Nature Genetics 14.
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42, S. 514 - 526 (2017)
Antagonistic Activities of Sox2 and Brachyury Control the Fate Choice of Neuro-Mesodermal Progenitors. Developmental Cell 15.
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6 (6), S. 752 - 764 (2017)
Pattering and gastrulation deffects caused by the tw18 lethal are due to loss of Ppp2r1a. Biology Open 16.
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538 (7624), S. 265 - 269 (2016)
Formation of novel chromatin domains determines pathogenicity of genomic duplications. Nature 17.
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34 (7), S. 1790 - 800 (2016)
Different Concentrations of FGF Ligands, FGF2 or FGF8 Determine Distinct States of WNT-Induced Presomitic Mesoderm. Stem Cells 18.
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26 (2), S. 183 - 191 (2016)
Exome Sequencing and CRISPR/Cas Genome Editing Identify Mutations of ZAK as a Cause of Limb Defects in Humans and Mice. Genome Research 19.
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575 (2 Pt 2), S. 438 - 451 (2016)
Analysis of the Fam181 gene family during mouse development reveals distinct strain-specific expression patterns, suggesting a role in nervous system development and function. Gene 20.
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161 (5), S. 1012 - 1025 (2015)
Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions. Cell