Journal Article (40)

1.
Journal Article
Hussong, M.; Kaehler, C.; Kerick, M.; Grimm, C.; Franz, A.; Timmermann, B.; Welzel, F.; Isensee, J.; Hucho, T.; Krobitsch, S. et al.; Schweiger, M. R.: The bromodomain protein BRD4 regulates splicing during heat shock. Nucleic Acids Research (London) 45 (1), pp. 382 - 394 (2017)
2.
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Castelo-Branco, P.; Leão, R.; Lipman, T.; Campbell, B.; Lee, D.; Price, A.; Zhang, C.; Heidari, A.; Stephens, D.; Boerno, S. T. et al.; Coelho, H.; Gomes, A.; Domingos, C.; Apolonio, J. D.; Schäfer, G.; Bristow, R. G.; Schweiger, M. R.; Hamilton, R.; Zlotta, A.; Figueiredo, A.; Helmut, K.; Sültmann, H.; Tabori, U.: A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: A retrospective cohort study. Oncotarget 36 (7), pp. 57726 - 57736 (2016)
3.
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Pasqualini, L.; Bu, H.; Puhr, M.; Narisu, N.; Rainer, J.; Schlick, B.; Schäfer, G.; Angelova, M.; Trajanoski, Z.; Börno, S. T. et al.; Schweiger, M. R.; Fuchsberger, C.; Klocker, H.: miR-22 and miR-29a are members of the androgen receptor cistrome modulating LAMC1 and Mcl-1 in prostate cancer. Molecular Endocrinology 29 (7), pp. 1037 - 1054 (2015)
4.
Journal Article
Zemojtel, T.; Köhler, S.; Mackenroth, L.; Jäger, M.; Hecht, J.; Krawitz, P.; Graul-Neumann, L.; Doelken, S.; Ehmke, N.; Spielmann, M. et al.; Oien, N. C.; Schweiger, M. R.; Krüger, U.; Frommer, G.; Fischer, B.; Kornak, U.; Flöttmann, R.; Ardeshirdavani, A.; Moreau, Y.; Lewis, S. E.; Haendel, M.; Smedley, D.; Horn, D.; Mundlos, S.; Robinson, P. N.: Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome. Science Translational Madicine 6 (252), 252ra123 (2014)
5.
Journal Article
Hussong, M.; Börno, S.; Kerick, M.; Wunderlich, A.; Franz, A.; Sültmann, H.; Timmermann, B.; Lehrach, H.; Hirsch-Kauffmann, M.; Schweiger, M. R.: The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. Cell Death and Disease 5, 5:e1195 (2014)
6.
Journal Article
Hussong, M.; Börno, S. T.; Kerick, M.; Wunderlich, A.; Franz, A.; Sültmann, H.; Timmermann, B.; Lehrach, H.; Hirsch-Kauffmann, M.; Schweiger, M. R.: The bromodomain protein BRD4 regulates the KEAP1/NRF2 dependent oxidative stress response. Cell Death and Disease 2014 (5), e1195 (2014)
7.
Journal Article
Röhr, C.; Kerick, M.; Fischer, A.; Kuehn, A.; Kashofer, K.; Timmermann, B.; Daskalaki, A.; Meinel, T.; Drichel, D.; Börno, S. et al.; Nowka, A.; Krobitsch, S.; McHardy, A. C.; Kratsch, C.; Becker, T.; Wunderlich, A.; Barmeyer, C.; Viertler, C.; Zatloukal, K.; Wierling, C.; Lehrach, H.; Schweiger, M.-R.: High-Throughput miRNA and mRNA Sequencing of Paired Colorectal Normal, Tumor and Metastasis Tissues and Bioinformatic Modeling of miRNA-1 Therapeutic Applications. PLoS One 8 (7), p. e67461 - e67461 (2013)
8.
Journal Article
Kacprzyk, L. A.; Laible, M.; Andrasiuk, T.; Brase, J. C.; Börno, S.; Falth, M.; Kuner, R.; Lehrach, H.; Schweiger, M. R.; Sultmann, H.: ERG Induces Epigenetic Activation of Tudor Domain-Containing Protein 1 (TDRD1) in ERG Rearrangement-Positive Prostate Cancer. PLoS One 8 (3), p. e59976 - e59976 (2013)
9.
Journal Article
Bu, H.; Schweiger, M. R.; Manke, T.; Wunderlich, A.; Timmermann, B.; Kerick, M.; Pasqualini, L.; Shehu, E.; Fuchsberger, C.; Cato, A. C. et al.; Klocker, H.: Anterior gradient 2 and 3--two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells. FEBS Journal 280 (5), pp. 1249 - 66 (2013)
10.
Journal Article
Grimm, C.; Chavez, L.; Vilardell, M.; Farrall, A.; Tierling, S.; Böhm, J. W.; Grote, P.; Lienhard, M.; Dietrich, J.; Timmermann, B. et al.; Walter, J.; Schweiger, M. R.; Lehrach, H.; Herwig, R.; Herrmann, B. G.; Morkel, M.: DNA–Methylome Analysis of Mouse Intestinal Adenoma Identifies a Tumour-Specific Signature That Is Partly Conserved in Human Colon Cancer. PLoS Genetics 9 (2), p. e1003250 - e1003250 (2013)
11.
Journal Article
Broer, L.; Lill, C.; Schuur, M.; Amin, N.; Roehr, C.; Bertram, L.; Ioannidis, J. P. A.; van Duijn, C. M.: Distinguishing true from false positives in genomic studies: p values. European Journal of Epidemiology 28 (2), pp. 131 - 138 (2013)
12.
Journal Article
Schweiger, M. R.; Barmeyer, C.; Timmermann, B.: Genomics and epigenomics: new promises of personalized medicine for cancer patients. Briefings in Functional Genomics 12 (5), pp. 411 - 21 (2013)
13.
Journal Article
Schweiger, M.-R.; Hussong, M.; Roehr, C.; Lehrach, H.: Genomics and epigenomics of colorectal cancer. Wiley Interdisciplinary Reviews: Cognitive Science 5 (2), pp. 205 - 219 (2013)
14.
Journal Article
Börno, S.; Fischer, A.; Kerick, M.; Falth, M.; Laible, M.; Brase, J. C.; Kuner, R.; Dahl, A.; Grimm, C.; Sayanjali, B. et al.; Isau, M.; Röhr, C.; Wunderlich, A.; Timmermann, B.; Claus, R.; Plass, C.; Graefen, M.; Simon, R.; Demichelis, F.; Rubin, M. A.; Sauter, G.; Schlomm, T.; Sültmann, H.; Lehrach, H.; Schweiger, M. R.: Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation. Cancer Discovery 2 (11), pp. 1024 - 1035 (2012)
15.
Journal Article
Querfurth, R.; Fischer, A.; Schweiger, M. R.; Lehrach, H.; Mertes, F.: Creation and application of immortalized bait libraries for targeted enrichment and next-generation sequencing. Biotechniques 52 (6), pp. 375 - 380 (2012)
16.
Journal Article
Welzel, F.; Kaehler, C.; Isau, M.; Hallen, L.; Lehrach, H.; Krobitsch, S.: FOX-2 dependent splicing of ataxin-2 transcript is affected by ataxin-1 overexpression. PLoS One 7 (5), p. e37985 - e37985 (2012)
17.
Journal Article
Lill, C. M.; Roehr, C.; McQueen, M. B.; Kavvoura, F. K.; Bagade, S.; Schjeide, B.-M.; Schjeide, L.; Meissner, E.; Zauft, U.; Allen, N. C. et al.; Liu, T.; Schilling, M.; Anderson, K. J.; Beecham, G.; Berg, D.; Biernacka, J. M.; Brice, A.; DeStefano, A. L.; Do, C. B.; Eriksson, N.; Factor, S. A.; Farrer, M. J.; Foroud, T.; Gasser, T.; Hamza, T.; Hardy, J. A.; Heutink, P.; Hill-Burns, E. M.; Klein, C.; Latourelle, J. C.; Maraganore, D. M.; Martin, E. R.; Martinez, M.; Myers, R. H.; Nalls, M. A.; Pankratz, N.; Payami, H.; Satake, W.; Scott, W. K.; Sharma, M.; Singleton, A. B.; Stefansson, K.; Toda, T.; Tung, J. Y.; Vance, J.; Wood, N. W.; Zabetian, C. P.; Young, P.; Tanzi, R. E.; Khoury, M. J.; Zipp, F.; Lehrach, H.; Ioannidis, J. P. A.; Bertram, L.; Parkinson's, G. E.; IPDGC; Consortium, P. D. G.; WTCCC2: Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database. PLoS Genetics 8 (3), p. e1002548 (2012)
18.
Journal Article
Meinel, T.; Schweiger, M. R.; Ludewig, A. H.; Chenna, R.; Krobitsch, S.; Herwig, R.: Ortho2ExpressMatrix--a web server that interprets cross-species gene expression data by gene family information. BMC Genomics 12, 12:483 (2011)
19.
Journal Article
Hallen, L.; Klein, H.; Stoschek, C.; Wehrmeyer, S.; Nonhoff, U.; Ralser, M.; Wilde, J.; Rohr, C.; Schweiger, M. R.; Zatloukal, K. et al.; Vingron, M.; Lehrach, H.; Konthur, Z.; Krobitsch, S.: The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2. Human Molecular Genetics 20, pp. 104 - 114 (2011)
20.
Journal Article
Hasler, R.; Kerick, M.; Mah, N.; Hultschig, C.; Richter, G.; Bretz, F.; Sina, C.; Lehrach, H.; Nietfeld, W.; Schreiber, S. et al.; Rosenstiel, P.: Alterations of pre-mRNA splicing in human inflammatory bowel disease. European Journal of Cell Biology 90 (6-7), pp. 603 - 11 (2011)
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