Publications
Selected publications
187 (23), pp. 6566 - 6583 (2024)
mTOR activity paces human blastocyst stage developmental progression. Cell
34 (9), pp. 700 - 702 (2024)
Embryos burn fat in standby. Trends in Cell Biology
31 (10), pp. 1625 - 1639 (2024)
TET activity safeguards pluripotency throughout embryonic dormancy. Nature Structural & Molecular Biology
40, pp. 25 - 49 (2024)
Dormancy, Quiescence, and Diapause: Savings Accounts for Life. Annual Review of Cell and Developmental Biology
26 (2), pp. 181 - 193 (2024)
FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy. Nature Cell Biology
25 (1), Article 6 (2024)
The double-edged sword of bivalency. Nature Reviews Molecular Cell Biology
34 (4), p. 589 - 589 (2024)
Combinatorial microRNA activity is essential for the transition of pluripotent cells from proliferation into dormancy. Genome Research
150 (14), dev201045 (2023)
On time: developmental timing within and across species. Development
149 (20), dev200679 (2022)
Hypoxia induces an early primitive streak signature, enhancing spontaneous elongation and lineage representation in gastruloids. Development
9, 708318 (2021)
Molecular Regulation of Paused Pluripotency in Early Mammalian Embryos and Stem Cells. Frontiers in Cell and Developmental Biology
12 (1), 4859 (2021)
Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells. Nature Communications
22 (3), pp. 369 - 383 (2018)
The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output. Cell Stem Cell
Inhibition of mTOR induces a paused pluripotent state.
Nature 2016 Dec 1;540(7631):119-123
Suv39h-Dependent H3K9me3 Marks Intact Retrotransposons and Silences LINE Elements in Mouse Embryonic Stem Cells.
Molecular Cell 2014 Jul 17;55(2):277-90
A transcription factor–based mechanism for mouse heterochromatin formation.
Nature Structural and Molecular Biology 2012 Oct;19(10):1023-30