Publications

Selected publications

van der Weijden, V. A.; Stötzel, M.; Fauler, B.; Iyer, D.; Shahraz, M.; Meierhofer, D.; Rulands, S.; Alexandrov, T.; Mielke, T.; Bulut-Karslioglu, A.: Metabolic enhancement of mammalian developmental pausing. (2022)
López-Anguita, N.; Gassaloglu, S. I.; Stötzel, M.; Typou, M.; Virta, I.; Hetzel, S.; Buschow, R.; Koksal, B.; Atilla, D.; Maitschke-Rajasekharan, R. et al.; Chen, R.; Mattei, A. L.; Bedzhov, I.; Meierhofer, D.; Meissner, A.; Veenvliet, J. V.; Bulut-Karslioglu, A.: Hypoxia induces a transcriptional early primitive streak signature in pluripotent cells enhancing spontaneous elongation and lineage representation in gastruloids. Development 149 (20), dev200679 (2022)
van der Weijden, V.; Bulut-Karslioglu, A.: Molecular Regulation of Paused Pluripotency in Early Mammalian Embryos and Stem Cells. (2021)
Aydan Bulut-Karslioglu, Hu Jin, Marcela Guzman-Ayala, Andrew JK Williamson, Miroslav Hejna, Anthony D Whetton, Jun S. Song, Miguel Ramalho-Santos
Chd1 regulates repair of promoter-proximal DNA breaks to sustain hypertranscription in embryonic stem cells
bioRxiv 659995; doi: https://doi.org/10.1101/659995
Bulut-Karslioglu, A.; Macrae, T. A.; Oses-Prieto, J. A.; Covarrubias, S.; Percharde, M.; Ku, G.; Diaz, A.; McManus, M. T.; Burlingame, A. L.; Ramalho-Santos, M.: The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output. Cell Stem Cell 22 (3), e8, pp. 369 - 383 (2018)
Aydan Bulut-Karslioglu, Steffen Biechele, Hu Jin, Trisha A. Macrae, Miroslav Hejna, Marina Gertsenstein, Jun S. Song, Miguel Ramalho-Santos.
Inhibition of mTOR induces a paused pluripotent state.
Nature 2016 Dec 1;540(7631):119-123
Aydan Bulut-Karslioglu, Inti A. De La Rosa-Velázquez, Fidel Ramirez, Maxim Barenboim, 
Megumi Onishi-Seebacher, Julia Arand, Carmen Galán, Georg E. Winter, Bettina Engist, Borbala Gerle, Roderick J. O’Sullivan, Joost H.A. Martens, Jörn Walter, Thomas Manke, Monika Lachner, Thomas Jenuwein.
Suv39h-Dependent H3K9me3 Marks Intact Retrotransposons and Silences LINE Elements in Mouse Embryonic Stem Cells.
Molecular Cell 2014 Jul 17;55(2):277-90
Aydan Bulut-Karslioglu, Valentina Perrera, Manuela Scaranaro, Inti Alberto de la Rosa-Velazquez, Suzanne van de Nobelen, Nicholas Shukeir, Johannes Popow, Borbala Gerle, Susanne Opravil, Michaela Pagani, Simone Meidhof, Thomas Brabletz, Thomas Manke, Monika Lachner, Thomas Jenuwein.
A transcription factor–based mechanism for mouse heterochromatin formation.
Nature Structural and Molecular Biology 2012 Oct;19(10):1023-30
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