Mutzel V, Okamoto I, Dunkel I, Saitou M, Giorgetti L, Heard E, Schulz EG
A symmetric toggle switch explains the onset of random X inactivation in different mammals.
Nature Structural and Molecular Biology 2019 Apr 82019 [Epub ahead of print]
Barros de Anrade e Sousa L, Jonkers I, Syx L, Chaumeil J, Picard C, Foret B, Chen C, Lis JT, Heard E, Schulz EG, Marsico A
Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features.
BioRxiv 2019
Gjaltema RAF, Schulz EG
CRISPR/dCas9 switch systems for temporal transcriptional control
Methods in Molecular Biology, 2018, 1767:167-185
Mutzel V, Okamoto I, Dunkel I, Saitou M, Giorgetti L, Heard E, Schulz EG
Two coupled feedback loops explain random mono-allelic Xist upregulation at the onset of X-chromosome inactivation
BioRxiv, 2017,
Schulz EG
X-chromosome dosage as a modulator of pluripotency, signalling and differentiation?
Philosophical Transactions of the Royal Society B: Biological Sciences, 2017, 372.1733, 20160366
Zhan Y, Mariani L, Barozzi I, Schulz EG, Blüthgen N, Stadler M, Tiana G, Giorgetti L
Reciprocal insulation analysis of Hi-C data shows that TADs represent a functionally but not structurally privileged scale in the hierarchical folding of chromosomes.
Genome Reseach, 2017 Mar;27(3):479-490
Schulz EG, Meisig J, Nakamura T, Okamoto I, Sieber A, Picard C, Borensztein M, Saitou M, Blüthgen N, Heard E
The Two Active X Chromosomes in Female ESCs Block Exit from the Pluripotent State by Modulating the ESC Signaling Network
Cell Stem Cell, 2014, 14:203-216
Schulz EG, Heard E
Role and control of X chromosome dosage in mammalian development
Current Opinion in Genetics & Development, 2013, 23(2): 109-115
Nora EP, Lajoie BR*, Schulz EG*, Giorgetti L*, Okamoto I, Servant N, Piolot T, van Berkum NL, Meisig J, Sedat J, Gribnau J, Barillot E, Blüthgen N, Dekker J# and Heard E#
Spatial partitioning of the regulatory landscape of the X-inactivation centre
Nature, 2012, 485(7398):381-5
Schulz EG, Nora EP, Heard E
Rnf12 – A Jack of All Trades in X Inactivation
PLoS Genetics, 2011, 7(1): e1002002
Schulz EG, Mariani L, Radbruch A and Höfer T
Sequential polarization and imprinting of type 1 T-helper lymphocytes by interferon-γ and interleukin-12
IMMUNITY, 2009, 30 (5), 673-683
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