A symmetric toggle switch explains the onset of random X inactivation in different mammals.
Nature Structural and Molecular Biology 2019 Apr 82019 [Epub ahead of print]
Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features.
CRISPR/dCas9 switch systems for temporal transcriptional control
Methods in Molecular Biology, 2018, 1767:167-185
Two coupled feedback loops explain random mono-allelic Xist upregulation at the onset of X-chromosome inactivation
X-chromosome dosage as a modulator of pluripotency, signalling and differentiation?
Philosophical Transactions of the Royal Society B: Biological Sciences, 2017, 372.1733, 20160366
Reciprocal insulation analysis of Hi-C data shows that TADs represent a functionally but not structurally privileged scale in the hierarchical folding of chromosomes.
Genome Reseach, 2017 Mar;27(3):479-490
The Two Active X Chromosomes in Female ESCs Block Exit from the Pluripotent State by Modulating the ESC Signaling Network
Cell Stem Cell, 2014, 14:203-216
Role and control of X chromosome dosage in mammalian development
Current Opinion in Genetics & Development, 2013, 23(2): 109-115
Spatial partitioning of the regulatory landscape of the X-inactivation centre
Nature, 2012, 485(7398):381-5
Rnf12 – A Jack of All Trades in X Inactivation
PLoS Genetics, 2011, 7(1): e1002002
Sequential polarization and imprinting of type 1 T-helper lymphocytes by interferon-γ and interleukin-12
IMMUNITY, 2009, 30 (5), 673-683