Long non-coding RNAs as regulators of transcription in human

Research report (imported) 2014 - Max Planck Institute for Molecular Genetics

Authors
Ørom, Ulf
Departments
Sofja Kovalevskaja Forschungsgruppe "Lange nicht-kodierende RNAs", gefördert durch die A. v. Humboldt Stiftung
Summary
The "Long non-coding RNAs" (ncRNAs) research group is focusing on the molecular mechanisms of long non-coding RNAs. In particular, the scientists are studying how these transcripts are involved in transcriptional regulation and long-range gene activating functions. The goal is a better understanding of fundamental processes underlying regulation of gene expression. The detailed understanding of the complex class of ncRNAs is limited, however, their importance for gene regulation and disease progression is obvious, following studies in both basic science as well as clinical research.

For the full text, see the German version.

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