Publikationen von Lars Wittler
Alle Typen
Zeitschriftenartikel (49)
1.
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623 (7988), S. 772 - 781 (2023)
Single-cell, whole-embryo phenotyping of mammalian developmental disorders. Nature 2.
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150 (22), dev202111 (2023)
Genome-wide identification of notochord enhancers comprising the regulatory landscape of the Brachyury (T) locus in mouse. Development 3.
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25, S. 1704 - 1715 (2023)
GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of long-range enhancers. Nature Cell Biology 4.
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55 (7), S. 1176 - 1185 (2023)
Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis. Nature Genetics 5.
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BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage. Development, dev.201450 (2023)
6.
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14, 1475 (2023)
Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve Split-Hand/Foot Malformation type 3. Nature Communications 7.
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150 (17), dev201562 (2023)
Induction of kidney-related gene programs through co-option of SALL1 in mole ovotestes. Development 8.
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Co-option of the transcription factor SALL1 in mole ovotestis formation. bioRxiv, 514220 (2022)
9.
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185 (20), S. 3689 - 3704 (2022)
Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes. Cell 10.
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54, S. 1238 - 1247 (2022)
Hijacking of transcriptional condensates by endogenous retroviruses. Nature Genetics 11.
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12, 3100 (2022)
Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction. Scientific Reports 12.
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25 (1), 103556 (2022)
Emergence and patterning dynamics of mouse-definitive endoderm. iScience 13.
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148 (23), dev200059 (2021)
A 37 kb region upstream of brachyury comprising a notochord enhancer is essential for notochord and tail development. Development 14.
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28 (7), S. 594 - 603 (2021)
Dnmt1 has de novo activity targeted to transposable elements. Nature Structural and Molecular Biology 15.
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Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator. Nature (2021)
16.
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118 (2), e2014481118 (2021)
A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions. Proceedings of the National Academy of Sciences of the United States of America 17.
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370 (6522), eaba4937 (2020)
Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites. Science 18.
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370 (6513), S. 208 - 214 (2020)
The mole genome reveals regulatory rearrangements associated with adaptive intersexuality. Science 19.
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8, 567 (2020)
SLC20A1 Is Involved in Urinary Tract and Urorectal Development. Frontiers in Cell and Developmental Biology 20.
Zeitschriftenartikel
584, S. 102 - 108 (2020)
Epigenetic regulator function through mouse gastrulation. Nature