Publications of Lars Wittler
All genres
Journal Article (49)
21.
Journal Article
51 (8), pp. 1263 - 1271 (2019)
Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture. Nature Genetics 22.
Journal Article
2019, 528877 (2019)
Preformed Chromatin Topology Assists Transcriptional Robustness of Shh during Limb Development. bioRxiv (Preprint Server) 23.
Journal Article
21 (3), pp. 305 - 310 (2019)
Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations. Nature Cell Biology 24.
Journal Article
50 (10), pp. 1463 - 1473 (2018)
Dynamic 3D chromatin architecture determines enhancer specificity and morphogenetic identity in limb development. Nature Genetics 25.
Journal Article
20 (6), pp. 599 - 607 (2018)
Noncoding copy-number variations are associated with congenital limb malformation. GENETICS IN MEDICINE 26.
Journal Article
50 (5), pp. 662 - 667 (2018)
Polymer physics predicts the effects of structural variants on chromatin architecture. Nature Genetics 27.
Journal Article
19 (1), pp. 118 - 134 (2018)
BRACHYURY directs histone acetylation to target loci during mesoderm development. EMBO Reports 28.
Journal Article
49 (10), pp. 1539 - 1545 (2017)
Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog). Nature Genetics 29.
Journal Article
42, pp. 514 - 526 (2017)
Antagonistic Activities of Sox2 and Brachyury Control the Fate Choice of Neuro-Mesodermal Progenitors. Developmental Cell 30.
Journal Article
6 (6), pp. 752 - 764 (2017)
Pattering and gastrulation deffects caused by the tw18 lethal are due to loss of Ppp2r1a. Biology Open 31.
Journal Article
538 (7624), pp. 265 - 269 (2016)
Formation of novel chromatin domains determines pathogenicity of genomic duplications. Nature 32.
Journal Article
34 (7), pp. 1790 - 800 (2016)
Different Concentrations of FGF Ligands, FGF2 or FGF8 Determine Distinct States of WNT-Induced Presomitic Mesoderm. Stem Cells 33.
Journal Article
26 (2), pp. 183 - 191 (2016)
Exome Sequencing and CRISPR/Cas Genome Editing Identify Mutations of ZAK as a Cause of Limb Defects in Humans and Mice. Genome Research 34.
Journal Article
575 (2 Pt 2), pp. 438 - 451 (2016)
Analysis of the Fam181 gene family during mouse development reveals distinct strain-specific expression patterns, suggesting a role in nervous system development and function. Gene 35.
Journal Article
161 (5), pp. 1012 - 1025 (2015)
Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions. Cell 36.
Journal Article
10 (5), pp. 833 - 839 (2015)
Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice. Cell Reports 37.
Journal Article
23 (20), pp. 5536 - 5544 (2014)
Genome-wide association study and mouse expression data identify a highly conserved 32 kb intergenic region between WNT3 and WNT9b as possible susceptibility locus for isolated classic exstrophy of the bladder. Human Molecular Genetics 38.
Journal Article
133, pp. 23 - 35 (2014)
SRF is essential for mesodermal cell migration during elongation of the embryonic body axis. Mechanisms of Development 39.
Journal Article
100 (6), pp. 512 - 517 (2014)
Classic bladder exstrophy: Frequent 22q11.21 duplications and definition of a 414 kb phenocritical region. Birth Defects Research Part A: Clinical and Molecular Teratology 40.
Journal Article
141 (11), pp. 2325 - 2330 (2014)
The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo. Development