Research Fields at the MPIMG
Research at the MPIMG spans several fields. The essence of our approach is to combine mechanistic investigation of genome function, bioinformatics, and genomic perturbation with developmental, population, and disease biology.
We combine methods from mathematics, statistics, and computer science to investigate important biological questions. Collaboration with experimental scientists is a hallmark of this research field, but we also pursue biological questions with theoretical analysis.
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We seek to understand the genetic basis of diseases. We study the link between epigenetic regulation and cancer, and how perturbations in genome function and organization contribute to rare genetic and other diseases.
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We are interested in fundamental questions of how the genome is regulated, organized and transcribed.
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We study how RNA is transcribed, processed and translated, particularly during brain development. We are also interested in how transposons shape our genome and how transposons shape evolution and affect post-transcriptional RNA processing.
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We are trying to unravel the mechanisms of early mammalian development, in particular how organs are built and how some mammalian species can pause their development.
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