Dahlem Colloquia in Molecular Genetics

Steven Henikoff: Genome-wide mapping of protein-DNA interaction dynamics

To attend the virtual lecture, please send us an email to the address above. You will receive a link on how to join timely before the lecture. [more]
Most of the work in Oded's lab is focused on transgenerational inheritance in general, and how neurons generate heritable memories in particular (see eg. Neuronal Small RNAs Control Behavior Transgenerationally). However, to quote Oded himself: "Everything connects in the end. We try very hard to let our curiosity guide us, and when the muse calls, we don't get in its way. "As a result, his lab has hijacked brain parasites to deliver therapeutic proteins in the brain and collaborated with biblical scholars, ancient DNA and metagenomics experts to piece together Dead Sea Scrolls fragments by sequencing ancient DNA obtained from the animal skin the scrolls are made of. I suggest you check out the paper published recently in Cell, it's certainly a most fascinating paper.Oded is also well-known for the radical ways he tries to transform science communication (see eg. https://www.woodstock.bio/).If you are interested in this virtual Dahlem Colloquium, please drop host Jesse Veenvliet an email to get a link to the meeting. [more]

Thomas Graf: From orchids to cell fate

Thomas has had an exceptionally prolific and diverse career, making fundamental discoveries on human leukemia viruses, co-discovering the first human oncogenes, and revealing molecular regulatory mechanisms of cellular differentiation ad reprogramming. [more]

Aoife McLysaght: Dosage sensitive genes in evolution and disease

Aoife McLysaght is head of the Smurfit Institute of Genetics at Trinity College Dublin and PI of the Molecular Evolution lab there. Her research focuses on fundamental principles of genome evolution, such as de novo gene evolution and gene/genome duplication, and relating these to the interpretation of human pathogenic mutations. Public outreach is a passion of Aoife's and she has contributed as a science communicator to the BBC podcast The Infinite Monkey Cage, the Dublin Science Gallery, the music and arts festival Electric Picnic and the Royal Institution Christmas Lectures. She is president of the Society for Molecular Biology and Evolution. [more]

Thomas Zwaka: The Unreasonable Effectiveness of Embryogenesis and Pluripotency: Mechanism and Mechanics of Cellular Conflicts

Thomas is a leading stem cell researcher who has been doing some really original work on the roles of transposon-derived transcription factors in stem cell control. He is also the editor in chief for Stem Cell Research. [more]

Maria-Elena Torres Padilla: Epigenetic mechanisms in early mammalian development

Ulrich Technau: The evolution of animal body plans – lessons from a sea anemone

Déborah Bourc'his: Protect or program: the dichotomy of DNA methylation in spermatogenesis

DNA methylation is a prevalent epigenetic mark in mammalian genomes, with essential roles for development. Over the past years, our team has made significant contribution in understanding the role of this mark for spermatogenesis and male fertility. I will present our latest work that demonstrates that sperm production relies on a division of labor between two DNA methylation enzymes, with specialized and non-redundant functions in developing germ cells: transposon control or stem cell homeostasis. [more]
As part of the GP write consortium, Romain Koszul is involved in rewriting the yeast (and other genomes). His lab engineers synthetic chromosomes and develops software to analyse 3D chromatin structure or to use Hi-C for genome assembly. With wet lab and computation, it’s fun for everyone! [more]
Does every gene affect the phenotypic variation in every complex trait? [more]

Didier Trono: The endovirome, its polydactyl controllers and the species-specificity of human transcriptional networks

The endovirome, its polydactyl controllers and the species-specificity of human transcriptional networks [more]
"Pervasive transcription: Origins and impact on the expression and stability of the yeast genome" [more]

Dahlem Colloquium: "SMCHD1: To Have, or not Have, a Nose"

"SMCHD1: To Have, or not Have, a Nose" [more]

Dahlem Colloquium: "Transcription during DNA damage"

"Transcription during DNA damage" [more]
"DNA methylation and the causes of Rett syndrome" [more]

Dahlem Colloquium: Modeling differentiation and stimulation response in single-cell genomics

Modeling differentiation and stimulation response in single-cell genomics [more]

Dahlem Colloquium: "Viewing nuclear architecture through the eyes of nocturnal mammals"

"Viewing nuclear architecture through the eyes of nocturnal mammals" [more]

Dahlem Colloquium: Long-term single-cell quantification: New tools for old questions

Long-term single-cell quantification: New tools for old questions [more]

Dahlem Colloquium: Function of cell cycle in stem cell differentiation

Function of cell cycle in stem cell differentiation [more]
A battlefield: Signaling during fertilization and embryo activation in plants [more]

Dahlem Colloquia: "Integration of regulatory RNAs in the cellular networks"

"Integration of regulatory RNAs in the cellular networks" [more]

Dahlem Colloquia: "Phenotypic noise in metabolic systems"

"Phenotypic noise in metabolic systems" [more]

Dahlem Colloquia: "In vivo selection to enhance cell and gene therapy for the liver"

“In vivo selection to enhance cell and gene therapy for the liver” [more]

Dahlem Colloquia: "Transcription of the genome: from molecular movies to regulatory systems"

"Transcription of the genome: from molecular movies to regulatory systems" [more]

Dahlem Colloquium: "Epigenetic regulation in development, aging and disease"

Epigenetic regulation in development, aging and disease [more]

Dahlem Colloquium: "balancing RNA levels"

"balancing RNA levels" [more]

Dahlem Colloquium: "Novel players regulating chromatin function"

"Novel players regulating chromatin function" [more]
"Restricting the extent of transcription across the mammalian genome to prevent the formation of pathological RNA" [more]

Dahlem Colloquium: "Predicting Functional Mechanisms from public CLIP-seq data"

"Predicting Functional Mechanisms from public CLIP-seq data" [more]

Dahlem Colloquium: "Regulation of geneexpression by RNA-binding proteins and non-coding RNAs"

"Regulation of geneexpression by RNA-binding proteins and non-coding RNAs" [more]
"3D genome organization and Polycomb function in epigenetic inheritance and developmental regulation" [more]

Dahlem Colloquium: "Regulation of large-scale chromatin architecture in mammalian cells"

"Regulation of large-scale chromatin architecture in mammalian cells" [more]

Dahlem Colloquium: “Developmental Control of Replication Timing and Chromosome Architecture”

“Developmental Control of Replication Timing and Chromosome Architecture” [more]

Dahlem Colloquium: “Developmental Modeling Of The Human Kidney”

“Developmental Modeling Of The Human Kidney” [more]

Dahlem Colloquium: “Dissecting RNA metabolism using single molecule microscopy”

“Dissecting RNA metabolism using single molecule microscopy” [more]

Dahlem Colloquium: “Increasing complexity of human proteome: from alternative splicing to alternative translation”

“Increasing complexity of human proteome: from alternative splicing to alternative translation” [more]

Dahlem Colloquium: "Epitranscriptomics – from basic principles to clinical insights"

"Epitranscriptomics – from basic principles to clinical insights" [more]

Dahlem Colloquium

"Stem cell models and non-coding RNAs in neurological disease." [more]

Dahlem Colloquium

“Intertwined evolution of mammalian coding and noncoding transcriptomes” [more]

Dahlem Colloquium

"The vulnerability of the developing human cortex to genetic and environmental causes of chromatin dysfunction: insights from 3D cortical organoids" [more]

Dahlem Colloquium

"Reading & Writing Genomes & Epigenomes: New Technologies & Applications." [more]

Dahlem Colloquium

“Genetic networks defining vertebrate trunk length“ [more]

Dahlem Colloquium

“Peaking into transcription using high-resolution genomics techniques“ [more]

Dahlem Colloquium

"What we can learn from ancient genetics" [more]

Dahlem Colloquium

“Building the mammalian embryo: partnership between embryonic and extra-embryonic stem cells in vivo and in vitro“ [more]

Dahlem Colloquium

"Evolution of regulatory landscapes" [more]

Dahlem Colloquium

  • Date: Dec 19, 2016
  • Time: 11:00 - 12:00
  • Speaker: Brian Munsky
  • Department of Chemical and Biological Engineering, School of Biomedical Engineering, Colorado State University, Fort Collins, USA
  • Location: Seminar Room SI, Tower 3
  • Host: Edda Schulz
"Using Noise to Discover Predictive Models of Signal-Activated Gene Expression" [more]

Dahlem Colloquium

"Feathered feet and fancy features: genetics and development of diversity in Darwin's pigeons" [more]

Dahlem Colloquium

"A cellular approach to angiogenesis; from live imaging to nanobodies" [more]

Dahlem Colloquium

"Genome regulation: Generating robustness and precision in developmental programs" [more]

Dahlem Colloquium

  • Date: Nov 17, 2016
  • Time: 11:00 - 12:00
  • Speaker: Tim Hubbard
  • Professor of Bioinformatics Head of Department of Medical & Molecular Genetics Director of Bioinformatics King's Health Partners/King's College London Faculty of Life Sciences & Medicine King's College London, UK
  • Location: Seminar Room SI, Tower 3
  • Host: Martin Vingron
"The 100,000 genomes project" [more]

Dahlem Colloquium

"Design Principles of Pluripotency" [more]

Dahlem Colloquium

"Epigenetic memory and beyond: Theoretical and experimental analysis of Polycomb/Trithorax regulation." [more]

Dahlem Colloquium

"Mechanisms of transgenerational epigenetic inheritance" [more]

Dahlem Colloquium

"Signaling Modules that Control Embryonic Stem Cell Identity" [more]

Dahlem Colloquium

"TADs, LNCKs and MEDs: Understanding the role of the epigenome in blood cancer initiation and progression" [more]

Dahlem Colloquium

"Structural organisation of the inactive X chromosome in the mouse" [more]

Dahlem Colloquium

"Illuminating genetic networks in cancer using CRISPR technology" [more]

Dahlem Colloquium

"Epigenetic mechanisms in stem cells and development" [more]

Dahlem Colloquium

"G Quadruplex Nucleic Acids" [more]

Dahlem Colloquium

"Ribonucleoprotein aggregates: where structural disorder and RNA-binding Ability meet" [more]

Dahlem Colloquia

"Evolution of gene expression: from mutation to polymorphism to divergence" [more]

Dahlem Colloquium

"Non-coding RNA-mediated assembly of heterochromatin - a kiss to remember" [more]

Dahlem Colloquium

"Annotation of cis-regulatory elements in the human brain." [more]
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