Journal Article (123)
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37 (6), 109967 (2021)
Chromatin-state barriers enforce an irreversible mammalian cell fate decision. Cell Reports 42.
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56 (21), e4, pp. 2995 - 3005 (2021)
Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages. Developmental Cell 43.
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RLM: Fast and simplified extraction of Read-Level Methylation metrics from bisulfite sequencing data. Bioinformatics 44.
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Smart-RRBS for single-cell methylome and transcriptome analysis. Nature Protocols 45.
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35 (17-18), pp. 1209 - 1228 (2021)
Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells. Genes and Development 46.
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12, 4897 (2021)
Topological isolation of developmental regulators in mammalian genomes. Nature Communications 47.
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Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells. Nature Communications 48.
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2021 (2021)
Dnmt1 has de novo activity targeted to transposable elements. Nature Structural and Molecular Biology 49.
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11 (11), e4042 (2021)
Generation of Mouse Pluripotent Stem Cell-derived Trunk-like Structures: An in vitro Model of Post-implantation Embryogenesis. Bio-protocol 50.
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39 (6), pp. 827 - 844 (2021)
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma. Cancer Cell 51.
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Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis. Science 52.
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2021, 20-1334 (2021)
Discovery of candidate DNA methylation cancer driver genes. Cancer Discovery 53.
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2021 (2021)
Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 54.
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370 (6522), eaba4937 (2020)
Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites. Science 55.
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2 (1), 2:1–16 (2020)
Pre-neoplastic alterations define CLL DNA methylome and persist through disease progression and therapy. Blood Cancer Discovery 56.
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Dissecting the DNA binding landscape and gene regulatory network of p63 and p53. eLife 57.
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584, pp. 102 - 108 (2020)
Epigenetic regulator function through mouse gastrulation. Nature 58.
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52 (8), pp. 819 - 827 (2020)
TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers. Nature Genetics 59.
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583, pp. 693 - 698 (2020)
Perspectives on ENCODE. Nature 60.
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52 (7), pp. 719 - 727 (2020)
Selective Mediator dependence of cell-type-specifying transcription. Nature Genetics