Systems Epigenetics Group
Dr. Edda Schulz
We are looking for students with a passion to solve mysteries driving fundamental biological processes, and the willingness and ability to work in an interdisciplinary environment. Previous experience with mathematical modeling, mammalian stem cells, CRISPR/Cas9, single-cell genomics or computational biology is an advantage, but not a requirement.
The Schulz lab studies epigenetic regulation with a systems biology approach. We seek to understand how threshold responses can establish transcriptional switches and epigenetic memory to allow quantitative information processing in mammalian cells. We use X-chromosome inactivation as a model to study epigenetic regulation, which is an essential developmental process. We operate on the interphase of biology, bioinformatics, physics and mathematics in a highly collaborative way to solve fundamental problems in gene regulation, by combining microscopy, single-cell genomics and genome engineering with mathematical modeling and computational biology.
For further information on the lab and the Institute visit the website of the Schulz lab.