Journal Article (868)

  1. 1.
    Lehrach, H.: Virtual Clinical Trials, an Essential Step in Increasing the Effectiveness of the Drug Development Process. Public Health Genomics (2051)
  2. 2.
    Aretz, I.; Hardt, C.; Wittig, I.; Meierhofer, D.: An impaired respiratory electron chain triggers down-regulation of the energy metabolism and de-ubiquitination of solute carrier amino acid transporters. Molecular and Cellular Proteomics 15 (5), pp. 1526 - 1538 (2016)
  3. 3.
    Broecker, F.; Hardt, C.; Herwig, R.; Timmermann, B.; Kerick, M.; Wunderlich, A.; Schweiger, M. R.; Borsig, L.; Heikenwalder, M.; Lehrach, H. et al.; Mölling, K.: Transcriptional signature induced by a C-terminal c-Src mutant in a human breast cell line. FEBS Journal 283 (9), pp. 1669 - 1688 (2016)
  4. 4.
    Broecker, F.; Hardt, C.; Herwig, R.; Timmermann, B.; Kerick, M.; Wunderlich, A.; Schweiger, M. R.; Borsig, L.; Heikenwalder, M.; Lehrach, H. et al.; Moelling, K.: Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line. The FEBS Journal 283 (9), pp. 1669 - 1688 (2016)
  5. 5.
    Castelo-Branco, P.; Leão, R.; Lipman, T.; Campbell, B.; Lee, D.; Price, A.; Zhang, C.; Heidari, A.; Stephens, D.; Boerno, S. T. et al.; Coelho, H.; Gomes, A.; Domingos, C.; Apolonio, J. D.; Schäfer, G.; Bristow, R. G.; Schweiger, M. R.; Hamilton, R.; Zlotta, A.; Figueiredo, A.; Helmut, K.; Sültmann, H.; Tabori, U.: A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: A retrospective cohort study. Oncotarget (2016)
  6. 6.
    Cui, H.; Schlesinger, J.; Schoenhals, S.; Tönjes, M.; Dunkel, I.; Meierhofer, D.; Cano, E.; Schulz, K.; Berger, M. F.; Haack, T. et al.; Abdelilah-Seyfried, S.; Bulyk, M. L.; Sauer, S.; Sperling, S. R.: Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA. Nucleic Acids Research (London) 46 (6), pp. 2538 - 2553 (2016)
  7. 7.
    The Berlin Aging Study II: An overview [Special Section]. Gerontology 62 (3), pp. 311 - 362 (2016)
  8. 8.
    Hussong, M.; Kaehler, C.; Kerick, M.; Grimm, C.; Franz, A.; Timmermann, B.; Welzel, F.; Isensee, J.; Hucho, T.; Krobitsch, S. et al.; Schweiger, M. R.: The bromodomain protein BRD4 regulates splicing during heat shock. Nucleic Acids Research (London) (2016)
  9. 9.
    Lienhard, M.; Grasse, S.; Rolff, J.; Frese, S.; Schirmer, U.; Becker, M.; Börno, S. T.; Timmermann, B.; Chavez, L.; Sültmann, H. et al.; Leschber, G.; Fichtner, I.; Schweiger, M. R.; Herwig, R.: QSEA-modelling of genome-wide DNA methylation from sequencing enrichment experiments. Nucleic Acids Research (London) (2016)
  10. 10.
    McGinn, S.; Bauer, D.; Bretfort, T.; Mertes, F.; Lehrach, H.; Sauer, S.: New technologies for DNA analysis - a review of the READNA Project. New biotechnology 33 (3), pp. 311 - 330 (2016)
  11. 11.
    Poznik, G. D.; Xue, Y.; Mendez, F. L.; Willems, T. F.; Massaia, A.; Wilson Sayres, M. A.; The 1000 Genomes Projekt, C.; Lehrach, H.; Sudbrak, R.; Albrecht, M. W. et al.; Amstislavskiy, V.; Borodina, T. A.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M.-L.: Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences. Nature Genetics 48 (6), pp. 593 - 599 (2016)
  12. 12.
    Bellander, M.; Bäckman, L.; Liu, T.; Schjeide, B.-M.; Bertram, L.; Schmiedek, F.; Lindenberger, U.; Lövdén, M.: Lower baseline performance but greater plasticity of working memory for carriers of the val allele of the COMT val158met polymorphism. Neuropsychology 29 (2), pp. 247 - 254 (2015)
  13. 13.
    Bellander, M.; Bäckman, L.; Liu, T.; Schjeide, B.-M.; Bertram, L.; Schmiedek, F.; Lindenberger, U.; Lövdén, M.: Lower baseline performance but greater plasticity of working memory for carriers of the val allele of the COMT val158met polymorphism. Neuropsychology 29 (2), pp. 247 - 254 (2015)
  14. 14.
    Bellander, M.; Bäckman, L.; Liu, T.; Schjeide, B.-M.; Bertram, L.; Schmiedek, F.; Lindenberger, U.; Lövdén, M.: Lower Baseline Performance but Greater Plasticity of Working Memory for Carriers of the Val Allele of the COMT Val(158)Met Polymorphism. Neuropsychology (2015)
  15. 15.
    Consortium, 1. G. P.; Lehrach, H.; Herwig, R.: A global reference for human genetic variation. Nature 526, pp. 68 - 74 (2015)
  16. 16.
    Domingo, A.; Westenberger, A.; Lee, L. V.; Braenne, I.; Liu, T.; Vater, I.; Rosales, R.; Jamora, R. D.; Pasco, P. M.; Cutiongco-de la Paz, E. M. et al.; Freimann, K.; Schmidt, T. G. P. M.; Dressler, D.; Kaiser, F. J.; Bertram, L.; Erdmann, J.; Lohmann, K.; Klein, C.: New insights into the genetics of X-linked dystonia-parkinsonism (XDP, DYT3). European Journal of Human Genetics 23, pp. 1334 - 1340 (2015)
  17. 17.
    Etchegaray, J. P.; Chavez, L.; Huang, Y.; Ross, K. N.; Choi, J.; Martinez-Pastor, B.; Walsh, R. M.; Sommer, C. A.; Lienhard, M.; Gladden, A. et al.; Kugel, S.; Silberman, D. M.; Ramaswamy, S.; Mostoslavsky, G.; Hochedlinger, K.; Goren, A.; Rao, A.; Mostoslavsky, R.: The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine. Nature Cell Biology 17 (5), pp. 545 - 557 (2015)
  18. 18.
    Fischer, U.; Forster, M.; Rinaldi, A.; Risch, T.; Sungalee, S.; Warnatz, H. J.; Bornhauser, B.; Gombert, M.; Kratsch, C.; Stutz, A. M. et al.; Sultan, M.; Tchinda, J.; Worth, C. L.; Amstislavskiy, V.; Badarinarayan, N.; Baruchel, A.; Bartram, T.; Basso, G.; Canpolat, C.; Cario, G.; Cave, H.; Dakaj, D.; Delorenzi, M.; Dobay, M. P.; Eckert, C.; Ellinghaus, E.; Eugster, S.; Frismantas, V.; Ginzel, S.; Haas, O. A.; Heidenreich, O.; Hemmrich-Stanisak, G.; Hezaveh, K.; Holl, J. I.; Hornhardt, S.; Husemann, P.; Kachroo, P.; Kratz, C. P.; Kronnie, G. T.; Marovca, B.; Niggli, F.; McHardy, A. C.; Moorman, A. V.; Panzer-Grumayer, R.; Petersen, B. S.; Raeder, B.; Ralser, M.; Rosenstiel, P.; Schäfer, D.; Schrappe, M.; Schreiber, S.; Schutte, M.; Stade, B.; Thiele, R.; Weid, N.; Vora, A.; Zaliova, M.; Zhang, L.; Zichner, T.; Zimmermann, M.; Lehrach, H.; Borkhardt, A.; Bourquin, J. P.; Franke, A.; Korbel, J. O.; Stanulla, M.; Yaspo, M. L.: Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. Nature Genetics 47 (9), pp. 1020 - 1029 (2015)
  19. 19.
    Fischer, U.; Forster, M.; Rinaldi, A.; Warnatz, H. J.; Sultan, M.; Lehrach, H.; Yaspo-Lehrach, M.-L.: Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. Nature Genetics (2015)
  20. 20.
    Fischer, U.; Forster, M.; Rinaldi, A.; Warnatz, H. J.; Sultan, M.; Amstislavskiy, V.; Ralser, M.; Lehrach, H.; Yaspo, M.-L.: Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. Nature Genetics (2015)
 
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