Contact & Head

Dr. Ulrich Stelzl
Former head of Max Planck Research Group
Phone:+43 316 380 -5397 (NEW)

Stelzl group in Graz

Ulrich Stelzl left the MPIMG in 2015 and holds a chair in Network Pharmacology at the University of Graz, Austria, now.


March 15

Towards the conditional interactome:

Phospho-tyrosine dependent protein-protein interaction network

in Mol Syst Biol

 Feb 14

Systematic human PPI analyses and PTMs:

Studying post-translational modifications with protein interaction networks

in Current Opinion in Structural Biology 

 Nov 13


Molecular interaction networks in the analyses of sequence variation and proteomics data

in Proteomics Clin Appl DOI: 10.1002/prca.201300039 

 March 13

Looking simultaneously at global protein phosphorylation, acetylation and ubiquitinylation patterns:

Dual Coordination of Post Translational Modifications in Human Protein Networks

in PLoS Computational Biology doi:10.1371/journal.pcbi.1002933  

 March 13

Improved interactome mapping:

A Y2H-seq approach defines the human methyltransferase interactome

in Nature Methods doi:10.1038/nmeth.2397

press release Die "Verpacker" der DNA können auch anders


Molecular Interaction Networks

Welcome to the OWL group "Molecular Interaction Networks" (guest group)

The group is focusing on the analysis of molecular interaction networks with the aim to understand the dynamics of molecular networks underlying cellular processes related to human disease. Experimental functional genomics techniques, e.g. HTP Y2H screening, are utilized in combination with biochemical, cell biological and computational methods.
Network biology offers a more comprehensive understanding of biology concomitantly improving the practice of medicine.

Currently we are working on three aspects of protein-protein interaction (PPI) research:

  •     Generation of accurate, high coverage PPI networks
  •     Condition dependent protein-protein interaction studies
  •     Integrative approaches to analyze PPI network dynamics

Please, see the current research report for a project overview.

For a start, a technology feature on interaction mapping free at Nature magazine ...

The interaction map by Monya Baker (Editor at Nature|Nature Methods)

A new discipline: network science !? An insight commentary at Nature Physics suggests ...

The network takeover by Albert-László Barabási (Boston|Massachusetts)

To get a quick idea about the "interactome" a technology feature at Nature magazine may be helpful ...

Interactome under construction by Laura Bonetta (Garrett Park|Maryland)

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