Molecular Embryology
	Team
	Projects
	Collaborations
	Publications
	Funding
	Links
	Press Release

2008 – 2012

1. The systems biology of network stress based on data generated from in vitro differentiated hepatocytes derived from individual-specific human iPS cells.

Co-ordinator: Dr James Adjaye

Consortium: Prof. Hans V. Westerhoff (Manchester UK), Prof. Hans Lehrach,

Prof. Ivano Bertini (Pisa Italy), Prof. George Church (Harvard Med. Sch. USA), Dr Ulrike Korf (DKFZ, Germany), Dr Christian Regenbrecht (Comprehensive Cancer Centre Charite- Germany), Dr Kurt Zatloukal (Graz Austria).

Funding scheme: ERASysBio (2010 - 2012)

2. Systems biology of self-renewal of human embryonic stem cells.

European Union funded project- ENFIN/FP6- LSHG-CT-2005-518254.

(06.02.2008 – 14.11.2010)

3. iPS cells from healthy and Alzheimer’s patients

Co-ordinator: Dr James Adjaye

Consortium: Prof. Dr. Christos Zouboulis (Dessau Medical Center)

Forschungsprojekten zur Gewinnung pluri-bzw. Multipotentet stammzellen (BMBF: 01GN0807)

(01.01.2009 – 31.10.2011)

4. Drug-based induction of pluripotent human stem cells (iPS cells) derived from human somatic cells Medizinische Systembiologie-BMBF: (0315398G)

(01.01.2009 – 31.12.2011)

5. Transcriptional and signaling mechanism(s) impacting the self-renewal and differentiation capacity of young and old mesenchymal stem cells.

DFG/SFB760: Musculoskeletal regeneration. (Oct. 2008 – Sept. 2009)

6. Identification and evaluation of stem cell like properties and putative new markers in cancer

stem cells (CSCs). Berliner Krebsgesellschaft e.V. (16.07.2008 – 28.07.2009)

7. Molecular characterisation of thrombin related signalling pathways in glioblastoma stem cells.

Wilhelm Sander-Stiftung (01.03.2009 – 28.02.2010)

8. Investigating the roles played by distinct ligands and receptors of the TGFß signaling pathway in

maintaining self-renewal and pluripotency in human embryonic and induced pluripotent stem cells.

BSRT: (2010 – 2012)

9. Generation and characterisation of induced pluripotent stem cells from human amniotic fluid cells.

BSRT: (2008 – 2011)

2005 - 2007

1. Genetic etiology of human longevity-NGFN II-EP

2. Stem-cell based liver regeneration- "Cell-based, Regenerative Medicine” – BMBF

3. Transcriptomics of bovine preimplantation development- Mechanisms of Embryo-maternal

Communication- AD184/5-1- (DFG / FOR478).

4. Functional characterisation of putative pluripotency controlling genes and their role in

establishing transcriptional networks and signalling pathways crucial to stem cell biology

(DFG- AD 184/4-1 / SPP1109)

last updated: 25 January, 2010