Max Planck Institute for Molecular Genetics

Max Planck Institute for Molecular Genetics - Ihnestraße 73 - 14195 Berlin - Germany - Phone: (+49 30) 8413 0 - Fax: (+49 30) 8413 1388
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Publications

Henning Stehr

PhD student in the Lappe group from October 2005 to May 2011

Note (April 2012): This page will not be updated anymore in the future. Please also see my Mendeley profile for my publications and activities.

Publications

Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics (2012). [PDF]
Armin Haupt*, Gerard Joberty*, Marcus Bantscheff, Holger Fröhlich, Henning Stehr, Michal R. Schweiger, Axel Fischer, Martin Kerick, Stefan Boerno, Andreas Dahl, Michael Lappe, Hans Lehrach, Cayetano Gonzalez, Gerard Drewes and Bodo M.H. Lange. BMC Cancer 2012 Jan 25;12(1):38. *shared first authorship

The structural impact of cancer-associated mutations in oncogenes and tumor suppressors (2011). [PDF]
Henning Stehr*, Seon-Hi J. Jang*, José M. Duarte, Christoph Wierling, Hans Lehrach, Michael Lappe, Bodo M.H. Lange.
Molecular Cancer 2011 May 16;10:54. *shared first authorship

CMView: Interactive contact map visualization and analysis (2011). [PDF]
Corinna Vehlow, Henning Stehr, Matthias Winkelmann, Jose M. Duarte, Lars Petzold, Juliane Dinse and Michael Lappe.
Bioinformatics 2011; doi: 10.1093/bioinformatics/btr163

Prediction of Native Contacts, 3D Structures and Model Quality Using Consensus Contacts (2010). [PDF]
Henning Stehr, Michael Lappe.
Critical assessment of methods for protein structure prediction (CASP9) - Abstract Book
(This method performed best in the contact prediction category in CASP9)

PDBWiki: success or failure? Factors for successful community annotation projects (2010). [PDF]
Dan M Bolser, Jose M Duarte, Jong Bhak, Henning Stehr.
Proceedings of the Workshop on Network Tools and Applications in Biology (NETTAB) 2010.

Optimal contact definition for reconstruction of Contact Maps (2010). [PDF]
Jose M Duarte, Rajagopal Sathyapriya, Henning Stehr, Ioannis Filippis and Michael Lappe.
BMC Bioinformatics 2010, 11:283.

PDBWiki: added value through community annotation of the Protein Data Bank (2010). [doi]
Henning Stehr, Jose M. Duarte, Michael Lappe, Jong Bhak, Dan M. Bolser.
Database: The Journal of Biological Databases and Curation 2010; doi: 10.1093/database/baq009

Defining an Essence of Structure Determining Residue Contacts in Proteins (2009). [doi]
Rajagopal Sathyapriya, Jose M. Duarte, Henning Stehr, Ioannis Filippis, Michael Lappe.
PLoS Computational Biology 5(12): e1000584. doi:10.1371/journal.pcbi.1000584

Designing evolvable libraries using multi-body potentials (2009). [doi]
Michael Lappe, Ganesh Bagler, Ioannis Filippis, Henning Stehr, Jose M. Duarte, Rajagopal Sathyapriya.
Current Opinion in Biotechnology 20(4): doi:10.1016/j.copbio.2009.07.008

Multiple Alignment of Contact Maps (2009). [doi]
Brijnesh Jain, Henning Stehr, Michael Lappe and Klaus Obermayer.
International Joint Conference on Neural Networks 2009: doi:10.1109/IJCNN.2009.5178907

Residue contact-count potentials are as effective as residue-residue contact-type potentials for ranking protein decoys (2008). [doi]
Dan M Bolser, Ioannis Filippis, Henning Stehr, Jose Duarte and Michael Lappe.
BMC Structural Biology 2008, 8:53: doi:10.1186/1472-6807-8-53

Constrained matching of large biological sequences. [PDF]
Henning Stehr
Diplomarbeit, TUHH / Universität Hamburg, 2005

An efficient group-by-sequence approach for identifying regulatory elements in whole genomes. [PDF]
Henning Stehr
Studienarbeit, TUHH / University of Waterloo (Canada), 2002

Projects
Some software projects I have initiated or significantly contributed to:

PDBWiki
A wiki for collaborative annotation of the Protein Data Bank

CMView
Open-source Java application for contact map analysis and interactive contact-based protein modeling.

OWL
Otto Warburg Java Library of Structural Bioinformatics. An open-source Java toolkit for protein sequence and structure analysis.

VMatch
Large scale sequence analysis software. A very efficient suffix-array based sequence matching and searching package.

Wer Wird Ingenieur?
Who wants to be an engineer? PHP based online game developed for Hamburg University of Technology.

Collaborations


ICGC Prostate Cancer
International Cancer Genome Consortium


Mutanom
Systems Biology of Genetic Diseases

ProSA
European Research Training Network on Selection and Analysis of Protein-Protein Interactions

Consert
Gene therapy for inherited diseases