Explanation of Data

BAND: The band nomenclature used refers to standard Giemsa stained (G-banded) chromosomes. The band localization was determined by G-banding the image of the metaphase spread to which the probe is hybridized through DAPI inversion and by correlating the fractional length and the genetic data. The accuracy of this measurement can vary and we suggest to use the genetic markers.

FLpter refers to the fractional length of the chromosome from the telomere of the p arm. We use the FLpter to measure the location of the probe. The range of the measurement is from 0 to 1, with the p arm telomere at 0.00 and the q arm telomere at position 1.00.

PROBES: Most of our YAC clones are derived from the CEPH library and have the standard CEPH number, ie., 685 b7 which represents the plate number and the coordinates. Probes preceded by a small i (ie. iG0924) are derived from the ICRF library. For most probes, the YAC insert has been isolated by PFGE and was amplified by DOP PCR

MARKERS refer to STSs (sequence-tagged sites). These markers were taken from the Whitehead Institute public database. http://www.genome.wi.mit.edu. The list is not complete. Note: Whitehead Institute markers are preceded by chromosome number, ie. WI-1154 from chromosome 11 is displayed as 11WI-1154.

cM: Centimorgans are recombination map units and refer to the genetic distance of probe markers from the short arm telomere. These data are considered as the best available for determining the linear YAC order.

SECOND SITES: Here we list second cytogenetic (ie. chromosome band) and genetic sites (ie. STSs).

NOTE: In a small percentage of cases (<5%) cytogenetic and genetic data do not correlate. The reason for this is unclear. For a detailed discussion please see: Bray-Ward et al. Genomics 32, 1-14 (1996). Probes that were previously FISH mapped by others (such as those reported in the above mentioned reference) have not all been re-mapped.