Max Planck Institute for Molecular Genetics
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  Nutrigenomics and Gene Regulation Group
 
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Selected publications

Peer-Reviewed Articles:

Weidner C, de Groot JC, Prasad A, Freiwald A, Quedenau C, Kliem M, Witzke A, Kodelja V, Han CT, Giegold S, Baumann M, Klebl B, Siems K, Müller-Kuhrt L, Schürmann A, Schüler R, Pfeiffer AFH, Schroeder FC, Büssow K, Sauer S. Amorfrutins are potent antidiabetic dietary natural products. Proc Natl Acad Sci U S A. 2012 April 16. [Epub ahead of print] (Abstract)

Kliem M, Sauer S. The essence on mass spectrometry based microbial diagnostics. Curr Opin Microbiol. 2012 Mar 10. [Epub ahead of print] (Abstract)

Mertes F, Elsharawy A, Sauer S, van Helvoort JM, van der Zaag PJ, Franke A, Nilsson M, Lehrach H, Brookes AJ. Targeted enrichment of genomic DNA regions for next-generation sequencing. Brief Funct Genomics. 2011;10(6):374-86. (Abstract)

Freiwald A, Mao L, Kodelja V, Kliem M, Schuldt D, Schreiber S, Franke A, Sauer S. Differential analysis of Crohn's disease and ulcerative colitis by mass spectrometry. Inflamm Bowel Dis. 2011;17(4):1051-2. (Abstract)

Sauer S, Kliem M. Mass spectrometry tools for the classification and identification of bacteria. Nature Rev Microbiol. 2010;8(1):74-82. (Abstract)

Haseneyer G, Stracke S, Piepho HP, Sauer S, Geiger HH, Graner G. DNA polymorphisms and haplotype patterns of transcription factors involved in barley endosperm development are associated with key agronomic traits. BMC Plant Biology. 2010;10:5. (Abstract)

Freiwald A, Sauer S. Phylogenetic classification and identification of bacteria by mass spectrometry. Nature Protoc. 2009;4(5):732-42. (Abstract)

Darii E, Lebeau D, Papin N, Rubina AY, Stomakhin A, Tost J, Sauer S, Savvateeva E, Dementieva E, Zasedatelev A, Makarov AA, Gut IG. Quantification of target proteins using hydrogel antibody arrays and MALDI time-of-flight mass spectrometry (A2M2S). N Biotechnol. 2009;25(6):404-16.(Abstract)

Konrad K, Dempfle A, Friedel S, Heiser P, Holtkamp K, Walitza S, Sauer S, Warnke A, Remschmidt H, Gilsbach S, Schäfer H, Hinney A, Hebebrand J, Herpertz-Dahlmann B. Familiality and molecular genetics of attention networks in ADHD. Am J Med Genet B Neuropsychiatr Genet. 2009 May 5. [Epub ahead of print] (Abstract)

Baek YS, Haas S, Hackstein H, Bein G, Santana MH, Lehrach H, Sauer S, Seitz H. Identification of novel transcriptional regulators involved in macrophage differentiation and activation in U937 cells. BMC Immunol. 2009;10(1):18. (Abstract)

Schimmelmann BG, Friedel S, Nguyen TT, Sauer S, et al. Exploring the genetic link between RLS and ADHD. J Psychiatr Res. 2009;43(10):941-5. (Abstract)

Stracke S, Haseneyer G, Veyrieras JB, Geiger HH, Sauer S, Graner A, Piepho HP. Association mapping reveals gene action and interactions in the determination of flowering time in barley. Theor Appl Genet. 2009;118(2):259-73. (Abstract)

Sauer S, Freiwald A, Maier T, Kube M, Reinhardt R, Kostrzewa M, Geider K. Classification and identification of bacteria by mass spectrometry and computational analysis. PLoS ONE. 2008;3(7):e2843. (Abstract)

Haseneyer G, Ravel C, Dardevet M, Balfourier F, Sourdille P, Charmet G, Brunel D, Sauer S, Geiger HH, Graner A, Stracke S. High level of conservation between genes coding for the GAMYB transcription factor in barley (Hordeum vulgare L.) and bread wheat (Triticum aestivum L.) collections. Theor Appl Genet. 2008;117(3):321-31. Epub 2008 May 17. (Abstract)

Friedel S, Saar K, Sauer S, et al. Association and linkage of allelic variants of the dopamine transporter gene in ADHD. Mol Psychiatry. 2007;12(10):923-33. Epub 2007 Apr 10. (Abstract)

Sauer S. The essence of DNA sample preparation for MALDI mass spectrometry. J Biochem Biophys Methods. 2007;70(2):311-8. (Abstract)

Sauer S, Reinhardt R, Lehrach H, Gut IG. Single Nucleotide Polymorphisms: Analysis by Mass Spectrometry. Nature Protoc. 2006;1(4):1761-1771. (Abstract)

Kepper P, Reinhardt R, Dahl A, Lehrach H, Sauer S. Matrix-assisted laser desorption/ionization mass spectrometric analysis of DNA on microarrays. Clin Chem. 2006;52(7):1303-10. Epub 2006 May 25. (Abstract)

Sauer S. Typing of single nucleotide polymorphisms by MALDI mass spectrometry: principles and diagnostic applications. Clin Chim Acta. 2006;363(1-2):95-105. (Abstract)

Sauer S, Konthur Z, Lehrach H. Genome projects and the functional-genomic era. Comb Chem High Throughput Screen. 2005;8(8):659-67. (Abstract)

Sauer S, Lange BM, Gobom J, Nyarsik L, Seitz H, Lehrach H. Miniaturization in functional genomics and proteomics. Nat Rev Genet. 2005;6(6):465-76. (Abstract)

Sauer S, Kepper P, Smyra A, Dahl A, Ferse FT, Lehrach H, Reinhardt R. Automated solid-phase extraction for purification of single nucleotide polymorphism genotyping products prior to matrix-assisted laser desorption/ionisation time-of-flight mass spectrometric analysis. J Chromatogr A. 2004;1049(1-2):9-16. (Abstract)

Bauer O, Guerasimova A, Sauer S, Thamm S, Steinfath M, Herwig R, Janitz M, Lehrach H, Radelof U. Multiplexed hybridizations of positively charge-tagged peptide nucleic acids detected by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Commun Mass Spectrom. 2004;18(16):1821-9. (Abstract)

Burgtorf C, Kepper P, Hoehe M, Schmitt C, Reinhardt R, Lehrach H, Sauer S. Clone-based systematic haplotyping (CSH): a procedure for physical haplotyping of whole genomes. Genome Research. 2003;13:2717-2724. (Abstract)

Sauer S, Lehrach H, Reinhardt R. MALDI mass spectrometry analysis of single nucleotide polymorphisms by photocleavage and charge-tagging. Nucleic Acids Res. 2003;31(11):e63. (Abstract)

Sauer S, Gut IG. Extension of the GOOD assay for genotyping single nucleotide polymorphisms by matrix-assisted laser desorption/ionization mass spectrometry. Rapid Commun Mass Spectrom. 2003;17(12):1265-72. (Abstract)

Sauer S, Gut IG. Genotyping single-nucleotide polymorphisms by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2002;782(1-2):73-87. (Abstract)

Sauer S, Gelfand DH, Boussicault F, Bauer K, Reichert F, Gut IG. Facile method for automated genotyping of single nucleotide polymorphisms by mass spectrometry. Nucleic Acids Res. 2002;30(5):e22. (Abstract)

Sauer S, Lechner D, Berlin K, Plançon C, Heuermann A, Lehrach H, Gut IG. Full flexibility genotyping of single nucleotide polymorphisms by the GOOD assay. Nucleic Acids Res. 2000;28(23):E100. (Abstract)

Sauer S, Lechner D, Berlin K, Lehrach H, Escary JL, Fox N, Gut IG. A novel procedure for efficient genotyping of single nucleotide polymorphisms. Nucleic Acids Res. 2000;28(5):E13. (Abstract)

German Articles:

Timmermann B, Sauer S, Dahl A, Reinhardt R "Genetische Variabilität des Menschen: Hochdurchsatztechnologien und Datenanalyse" Laborwelt 5(5) 16-17, 2004

Timmermann B, Sauer S, Omran H, Lehrach H, Sudbrak R, Reinhardt R "Vergleichende Sequenzierung von Kandidatengenen: Die Resequencing-Plattform am MPI-MG". GenomXpress 1-2004, 17-19, 2004

Book Chapters

Sauer S. "Tools for Detection of DNA Polymorphisms", ed. T.P. Begley, Wiley Encyclopedia of Chemical Biology, Wiley& Sons, 2009

Sauer S. "Chapter 20: Matrix-assisted Laser Desorption/Ionization Mass Spectrometry: Principles and Applications in Life Sciences", Lasers in Chemistry, Volume 1, 593-616, Wiley-VCH, 2008

Sauer S. "SNP Detection and Mass Spectrometry", Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine, Springer, 2006


Patents:

I.G. Gut, D. Lechner and S. Sauer, "Sample Generation for genotyping by mass spectrometry", EP 1170379A1

S. Sauer, K. Büssow, H. Lehrach "Method for high-throughput screening of test molecules binding to target molecules I", patent submitted to the European Patent Office (The Hague)

S. Sauer, K. Büssow, H. Lehrach "Method for high-throughput screening of test molecules binding to target molecules II", patent submitted to the European Patent Office (The Hague)


Non Peer-Reviewed Articles:

Han CT, Holzhauser S, Sauer S. Nutrigenomics and Gene Regulation. Journal of Biotechnology in Berlin-Brandenburg: BioTOPics 36_Molecular Nutrition Research and Food Technology. 2009;36:14-15. (Full-Text)

Sauer S. MALDI mass spectrometry detection of oligonucleotides. Bio Tech International. 2007;19(1):11-13. (FullText)

 

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Last updated: 17/04/12.