Selected Publications:

F. Schluenzen, R. Zarivach, J. Harms, A. Bashan, A. Tocilj, R. Albrecht, A. Yonath and F. Franceschi, Structural basis for the interaction of antibiotics with the peptidyl transferase center in eubacteria. Nature, 413, 814-821 (2001).

J. Harms, F. Schluenzen, R. Zarivach, A. Bashan, S. Gat, I. Agmon, H. Bartels, F. Franceschi & A. Yonath, High resolution structure of the large ribosomal subunit from a mesophilic eubacterium. Cell,
107, 679-688 (2001)

A. Bashan, I. Agmon, R. Zarivach, F. Schluenzen, J. Harms, M. Pioletti, H. Bartels, M. Gluehmann, H.A.S. Hansen, T. Auerbach, F. Franceschi and A. Yonath. High resolution structures of ribosomal subunits: initiation, inhibition and conformational variability. Cold Spring Harbor Symposium 66, in the press (2001)

M. Pioletti, F. Schluenzen, J. Harms, R. Zarivach, M. Glueman, H. Avila, A. Bashan, H. Bartels, T. Auerbach, C. Jacobi, Hartsch T, A. Yonath and F. Franceschi, Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3. EMBO J. 20(8), 1829-1839 (2001)

Henn A., Medalia O., Shi S., Steinberg M., Franceschi F. and Sagi I. Visualization of unwinding activity of duplex RNA by DbpA, a DEAD box helicase, at single-molecule resolution by atomic force microscopy. Proc. Natl. Acad. Sci. USA 98: 5007-5012 (2001)

F. Schluenzen, A. Tocilj, R. Zarivach, J. Harms, M. Glueman, D. Janell, A. Bashan, H. Bartels, I. Agmon, F. Franceschi and A. Yonath, Structure of functionally activated small ribosomal subunit at 3.3 A resolution. Cell 102, 615-623 (2000)

A. Yonath and F. Franceschi, Ribosomes, In:" Encyclopedia of Molecular Biology" (T.E. Creighton, Ed.), J.Wiely & Sons, 2197-2202 (2000)

A. Tocilj, F. Schluenzen, H.A.S.Hansen, A. Bashan, D. Janell, M. Glueman, H. Bartels, J. Harms, I. Agmon, F. Franceschi, and A. Yonath, The small ribosomal subunit from Thermus thermophilus at 4.5 A resolution: pattern fittings and the identification of a functional site. Proc. Natl. Acad. Sci. USA 96, 14252-7 (1999)

S. Weinstein, W. Jahn, C. Glotz, F. Schluenzen, I. Levin, D. Janell, J. Harms, I. Kolln, H.A.S. Hansen, M. Glueman, W.S. Bennett, H. Bartels, A. Bashan, I. Agmon, M. Kessler, M. Pioletti, H. Avila, K. Anagnostopoulos, M. Peretz, T. Auerbach, F. Franceschi and A. Yonath, Metal compounds as tools for the construction and the interpretation of medium- resolution maps of ribosomal particles. J. Structural Biology 127, 141-151 (1999)

Morlang, S., Weglöhner, W. and Franceschi F. Hera from Thermus thermophilus: the first thermostable DEAD-box helicase with a RNAse P protein motif. J. Mol. Biol. 294, 795-805 (1999)

J. Harms, A. Tocilj, I. Levin, I. Agmon, H. Stark, I. Kolln, M. van Heel, M. Cuff, F. Schluenzen, A. Bashan, F. Franceschi, and A. Yonath, Elucidating the medium-resolution structure of ribosomal particles: an interplay between electron cryo- microscopy and X-ray crystallograhy. Structure 7, 931-41 (1999)

M. Simitsopoulou, H. Avila and F. Franceschi. Ribosomal gene disruption in the extreme thermophile Thermus thermophilus HB8: Generation of a mutant lacking ribosomal protein S17. Eur. J. Biochem. 266, 524-532 (1999)

P. Tsiboli, D. Triantafillidou, F. Franceschi and D. Choli-Papadopoulou. Studies on the Zn containing S14 ribosomal protein from Thermus thermophilus. Eur. J. Biochem. 256, 136-141 (1998)

A. Yonath, J. Harms, H.A. Hansen, A. Bashan, F. Schluenzen, I. Levin, I. Koelln, A. Tocilj, I. Agmon, M. Peretz, H. Bartels, W.S. Bennett, S. Krumbholz, D. Janell, S. Weinstein, T. Auerbach, H. Avila, M. Piolleti, S. Morlang, and F. Franceschi, Crystallographic studies on the ribosome, a large macromolecular assembly exhibiting severe nonisomorphism, extreme beam sensitivity and no internal symmetry. Acta Crystallogr. A, 54, 945-55 (1998)

A. Yonath and F. Franceschi, Functional universality and evolutionary diversity: insights from the structure of the ribosome. Structure 6, 679-84 (1998)

Böddeker, N., Stade, K., and Franceschi F. Characterization of DbpA, an Escherichia coli DEAD box protein with ATP independent RNA unwinding activity. Nucleic Acids Research , 25: 537-544 (1997).

A. Yonath and F. Franceschi, New RNA recognition features revealed in ancient ribosomal proteins. Nature Struct. Biol. 4, 3-5 (1997)

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